A new review from our lab exploring how the blood-brain barrier (BBB) can be used as a treatment target for neurodegenerative disorders
https://tandfonline.com/doi/10.1080/17425247.2025.2480654?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
TL;DR → Here are a few key highlights 👇
https://tandfonline.com/doi/10.1080/17425247.2025.2480654?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
TL;DR → Here are a few key highlights 👇
Comments
We think that more attention should focus on therapeutics to preserve BBB functions when considering treatments of neurodegenerative diseases including AD.
One option is to enhance the clerance function for neurotoxic proteins at the BBB e.g. targeting lipoprotein receptors (LRP)