This preprint explores how past SARS-CoV-2 exposure shapes immunity. Adults imprinted by early strains target RBD, while XBB*-infected infants focus on NTD. Vaccination shifts infants’ response to RBD but with different targets. #virology #COVID19 https://www.biorxiv.org/content/10.1101/2025.01.17.633612v1.full
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