Changes in endothelial cell large conductance calcium-activated potassium channels (BKCa) after #hypoxia may explain the altered myogenic tone which impacts blood flow following ischemic #stroke.
#ionchannels #vascularbiology #physiology #cerebrovascular #endothelium #neurosky #emedsky #medsky
#ionchannels #vascularbiology #physiology #cerebrovascular #endothelium #neurosky #emedsky #medsky
Reposted from
Christian Staehr
🚨 Publication alert!🚨 Our new study (onlinelibrary.wiley.com/doi/full/10....) in Acta Physiologica shows that #stroke/#hypoxia induces the expression of BK-Ca channels in the #cerebrovascular #endothelium across species 🧔🏻♂️🐭🐷🐀. These channels, absent in normoxia, regulate post-stroke arterial tone.
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