Beautiful conceptual work here. Challenging mainstream world view of oncogenes being deterministic and with an average effect of promoting cancer. In fact rare stochastic escape from homeostasis might be enough for tumor progression.
Reposted from
bioRxiv Cancer Bio
The inherent fragility of collective proliferative control https://www.biorxiv.org/content/10.1101/2024.01.23.576783v1
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