aleprigio.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Our paper showing that ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST is now published @cp-cellmetabolism.bsky.social Thanks to everyone involved! www.cell.com/cell-metabol...

submitted 8 days ago • 6 comments

I'm co-organizing a Cell Symposia on Metabolites in Organellar Communication with @robzonculab.bsky.social, Kivanc Birsoy, and Allyson Evans (@cp-cellmetabolism.bsky.social). It will be in Sitges May 11-13. Submit an abstract by Feb 14. Hope to see you in Spain! cell-symposia.com/metabolites-...

submitted 12 days ago • 0 comments

SY-Stem 2025 Symposium: Registration deadline on February 15th! SY-Stem - a symposium focusing on the next generation of stem cell researchers - is organized by IMBA and @impvienna.bsky.social. Register online: bit.ly/4jekaDg Check out the program: bit.ly/4jDioM6

submitted 20 days ago • 0 comments

🧬🧪Protein codes promote selective subcellular compartmentalization | Science www.science.org/doi/10.1126/... Henry Kilgore @itamarchinn.bsky.social @pgmikhael.bsky.social Ilan Mitnikov, et al. @aihealthmit.bsky.social @whiteheadinstitute.bsky.social @mitofficial.bsky.social

submitted 16 days ago • 3 comments

The U.S. has had probably the best university system in the world since the late 1940s; government investments (state and federal) drove that success. That may have changed overnight. 🧵🧪

submitted 17 days ago • 43 comments

1/n 🚨 New Review Alert! 🚨 Excited to share our open-access review, Choroid Plexus Pathophysiology, published in Annual Review of Pathology! The ChP is a small but mighty structure at the heart of CNS health, disease, and therapeutic potential. #science 🧪 www.annualreviews.org/content/jour...

submitted 31 days ago • 1 comment

New year, new version of mitoXplorer 3.0 (mitoxplorer3.ibdm.univ-amu.fr) : mine your single-cell RNA-seq data from a mitochondrial perspective by creating cell-type specific pseudo-bulks or by looking at mitochondrial variability on single-cell level. Check it out at doi: doi.org/10.1101/2024...

submitted 54 days ago • 1 comment

Very interesting opinion piece. The only thing I would disagree with is the line: "what can be done? The sad answer is not that much". People (in US and outside) need to fight this at all levels. Our world as we know it is on the line.

submitted 20 days ago • 0 comments

Time for some mito-business. Or should we say methyl-business?? Let's ask our speaker Thomas MacVicar. This thursday, usual time and place.

submitted 22 days ago • 0 comments

Delighted to share our latest review article summarizing the use of induced pluripotent stem cells (iPSCs) to model mitochondrial disorders with 2D and 3D organoid approaches. www.sciencedirect.com/science/arti...

submitted 24 days ago • 0 comments

1/ Pleased to share our review, published today @natrevimmunol.bsky.social, highlighting how biomolecular condensates enhance the precision and flexibility of gene regulatory networks that guide fate decisions during normal and pathological immune cell development. www.nature.com/articles/s41...

submitted 28 days ago • 2 comments

My regular reminder that there is an open call @pasteur.fr for junior group leader covering various axis (including topics related to development biology), open till Feb. 28th. Don't hesitate to DM me or reach out by email if you want to get more context. research.pasteur.fr/fr/call/call...

submitted 29 days ago • 0 comments

Düsseldorf stellt sich quer und Mitglieder der @hhu.bsky.social sind dabei! Wer ebenfalls Flagge für Demokratie zeigen möchte und dafür noch ein Plakatmotiv braucht, kann sich gerne bei uns (auch per PM) melden - wir teilen unseren #HeineGegenRechts mit euch!

submitted 29 days ago • 1 comment

Sad to see webpages of NIH diversity supplements taken down. I know this was suspected to happen, but it’s heartbreaking to see. www.nature.com/articles/d41... Eg., NIMH www.nimh.nih.gov/about/organi...

submitted 32 days ago • 2 comments

We are recruiting 2 postdocs to help us understand the mechanisms underlying HSV-1 latency. You will be part of a collaborative team & receive extensive mentorship to develop your own independent line of research. #stemcells #virology Please share 🙏 careers.humantechnopole.it/o/postdoc-ha...

submitted 40 days ago • 0 comments

"The science of extreme longevity continues as an immense joke." —The first man to “survive” past 110 actually died at 65. —Blue zones are a myth —Pervasive false claims about longevity and supercentenarians Gift link www.nytimes.com/2025/01/20/o...

submitted 36 days ago • 26 comments

Brains minimize energy consumption while maximizing computation. In humans, this trade-off is reconciled towards complex behaviors & hence relatively high energy use Review & synthesis with @sharnajamadar.bsky.social @annabhlr.bsky.social & Hamish Deery tinyurl.com/47c9n65w osf.io/preprints/os...

submitted 36 days ago • 1 comment

The deadline to apply for the MBL Physiology course is fast approaching, January 27th! Consider applying to this amazing, life-changing research discovery experience in Woods Hole! www.mbl.edu/education/ad...

submitted 36 days ago • 0 comments

Mitochondria consist of networks of cylindrical tubes, right? Not necessarily! - in our new preprint, @gavsturm.bsky.social investigates how mitochondria transiently adopt a beads-on-a-string morphology www.biorxiv.org/content/10.1...

submitted 64 days ago • 6 comments

The @ibdm.bsky.social look for new team leaders! Apply by March 30th if you want to join us to study developmental biology as a PI! www.ibdm.univ-amu.fr/we-are-recru...

submitted 39 days ago • 0 comments

A couple of weeks left to apply to join Development's Pathway to Independence programme Support & mentoring for post-docs on the academic job market Deadline: January 31 journals.biologists.com/dev/pages/pi...

submitted 39 days ago • 0 comments

Fine-tuning tumor immunogenicity with mitochondrial complex I Our views on a very cool paper from @ppuigserverb.bsky.social we hope you like it! www.nature.com/articles/s43...

submitted 39 days ago • 1 comment

Check out our latest Research Highlight by @daniela-senft.bsky.social! 👀👇

submitted 42 days ago • 0 comments

Vielen Dank an Sigrid März @spektrum.de für dieses Interview, in dem wir über Mitochondrien in der Neurodegeneration und Fortschritte beim Leigh-Syndrom sprechen. www.spektrum.de/news/mitocho...

submitted 42 days ago • 0 comments

‘Expansion microscopy’ turns ten: how a tissue-swelling method brought super-resolution imaging to the masses @nature.com @natureportfolio.bsky.social 🧪 www.nature.com/articles/d41...

submitted 42 days ago • 0 comments

We begin the New Year with two preprints on hypothalamic development. The first, part of a long-term collaboration with Marysia Placzek’s group, investigates the organization of the developing forebrain, and show that current models are (mostly) incorrect./1 www.biorxiv.org/content/10.1...

submitted 44 days ago • 3 comments

www.sciencedirect.com/science/arti... Coenzyme Q10 deficiency disrupts lipid metabolism by altering cholesterol homeostasis in neurons

submitted 46 days ago • 0 comments

Super interesting article by Martin Picard

submitted 46 days ago • 1 comment

Exciting work! A mitochondrial perspective of scRNAseq datasets!

submitted 47 days ago • 1 comment

I think the field needs to reconsider the widespread concept that microglia are The most important factor controlling synaptic pruning.🧠🧪 We offered our Perspective on whether they are hunters or gatherers of synaptic debris here www.nature.com/articles/s41...

submitted 48 days ago • 0 comments

Very important study for everyone working in neurodevelopment and/or with microglia. www.nature.com/articles/s41...

submitted 49 days ago • 0 comments

🗓️ Mark your calendar: May 19-21, 2025 Registration is now open for the Neurogenomics Conference @humantechnopole.bsky.social: humantechnopole.it/en/trainings.... Come and join us in beautiful Milan! Incredibly excited to welcome a truly stellar line-up of speakers: including... 1/2

submitted 50 days ago • 1 comment

Thrilled & immensely honoured to receive the Italian Science Fund (FIS) Starting Grant. We will uncover the mechanisms underlying HSV-1 latency and reactivation in human, disease relevant, cells. Postdoc positions in virology and human stem cell biology @humantechnopole.bsky.social available soon!

submitted 80 days ago • 8 comments

New podcast: Disease Models in Leigh Syndrome Apple: podcasts.apple.com/gb/podcast/j... Spotify: open.spotify.com/episode/2wrv... Or search for JIMD Podcasts wherever you like to listen #LeighSyndrome #MitoDisease #viagra @aleprigio.bsky.social @mitotalks.bsky.social

submitted 53 days ago • 0 comments

Thanks to @jimd-editors.bsky.social for having us on their fantastic podcast series. We discussed about Leigh syndrome, mitochondrial diseases, modeling tools and potential future treatments. open.spotify.com/episode/2wrv...

submitted 53 days ago • 2 comments

#lipids and #organelle conversations. Happy 2025! www.sciencedirect.com/science/arti...

submitted 54 days ago • 0 comments

I ran 2150 km this year. So grateful for being able to do that. Health is such a fragile thing. Hopefully my knee will heal soon and I can get back to running in the new year..🤞

submitted 64 days ago • 0 comments

PhD Job alert! If you are interested in #metabolism, neuronal function, #ipsc and Chip technology, consider applying for this position. www.radboudumc.nl/en/vacancies...

submitted 72 days ago • 0 comments

How is metabolism interconnected with cellular dynamics? We are @emaniou.bsky.social and @hpscenthusiast.bsky.social and through an energy inexpensive process, we will highlight advances in mechano-metabolism and related fields. @epimechfc.bsky.social

submitted 73 days ago • 1 comment

Bad bar charts are pervasive across biology Scientific ‘shorthand’ could be introducing data distortions into published papers. Amanda Heidt writes Nature. www.nature.com/articles/d41...

submitted 77 days ago • 5 comments

First post on bsky! 🚨 Looking for a postdoc! 🚨 Excited to recruit a computational researcher to join my lab @YaleGenetics & work on exciting projects in human & mitochondrial genomics, building tools to link genetic variation to disease. Enquires welcome! Details 👉 www.thelakelab.org/yale-genetic...

submitted 81 days ago • 0 comments