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alexludwig.bsky.social
Cell biologist and nature lover interested in epithelial cell junctions, mechanobiology, and cell polarity. Asst Prof at NTU Singapore. Check out the ALab homepage: https://blogs.ntu.edu.sg/alabntusg/
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Another beautiful tight junction. This time with scale bar :)

Not bad for a conventionally fixed and dehydrated TEM sample. No HPF/FS. OTO method. Stains the kissing points quite nicely.

First official post! A new paper out about #cytokinesis in #epithelia www.embopress.org/doi/full/10.... Explore our journey as we uncover how regulators of cell-cell and cell-matrix interactions modulate cytokinesis efficiency, while revealing new roles for the Dystrophin-Dystroglycan complex.

This is sabotage! And this may well be just the beginning.

You don’t have to be German to know what this stands for - it’s clear as mud - and it’s disgusting!

iAPEX: Improved APEX-based proximity labeling for subcellular proteomics using an enzymatic reaction cascade https://www.biorxiv.org/content/10.1101/2025.01.10.632381v1

Our #CryoET paper on ciliary rootlet ultrastructure from mouse retina is now out in @elife.bsky.social! Have a peek with this video or dive deeper at bit.ly/3ZJzhgc. Big thanks to @carter-lab.bsky.social and #teamtomo. #CryoET #CryoEM #Cilia #Rootlet #Centriole #Research #Science

Mind blowing! Look at those nuclear pores.

Still one of my favourite tomograms, recorded ages ago at NCMIR (UCSD). It shows interconnected networks of caveolae (labeled with a miniSOG probe) at the rear of RPE1 cells. Bummer we so far haven't been able to image such networks in larger cell volumes; it's a lot of membrane that's stored here.

Woah. Bluesky seems to be much more than a much needed alternative to X. I didn't expect this big a science community here tbh. I love the start up packages; really cool to connect with so many people I never met or even heard of. Since I'm new to this, I'll briefly introduce my lab and what we do.

This will be a fantastic meeting! Looking forward to it