Profile avatar
alexswarbrick.bsky.social
Professor of Breast & Prostate cancer, Melanoma research. Tumour Ecosystems, Single Cell and Spatial Genomics. Sydney/Gadigal Australia. Views are my own & not my employers
9 posts 1,997 followers 599 following
Regular Contributor
Posts 19 Comments 3

The four basic kinds of scientific papers: 1. Noise (no claim and no evidence) 2. Resource (no claim but lots of data) 3. Conjecture (makes a claim, but no evidence) 4. Scientific advance (both makes a claim and presents evidence)

submitted 60 days ago • 5 comments

If you are interested in joining our growing Lab of CAFs enthusiasts @mdanderson.bsky.social and to understand how CAF metabolism can be harnessed to modulate the immune-TME, we are looking for talented postdocs! 👇🏻 jobs.mdanderson.org/search/jobde...

submitted 75 days ago • 0 comments

Wanted- *Bioinformatics Research Assistant*. Projects include generation of an international, large-scale, multi-omic breast cancer atlas and understanding response to immunotherapy in breast cancer, prostate cancer and melanoma. Great training opportunities 🧬💻 More info ⤵️ tinyurl.com/33wxkswz

submitted 77 days ago • 0 comments

Jobortunities: Shortly advertising for 2 positions, both working on the Breast Cancer Atlas, in Sydney. - Wet lab research assistant: mol bio +/- pathology desirable - Comp. Research Assistant: scRNA-Seq, spatial transcriptomics and ML Details to follow, DM or email if you are a great fit.

submitted 81 days ago • 0 comments

Im thrilled for this recogntion of Christina Curtis and Steffi Oesterreich by the @theaacr.bsky.social at @sabcs.bsky.social. I'm in awe of their achievements and impacts on breast cancer research. They are also two of the nicest people you'll ever meet ! sabcs.cmail19.com/t/d-l-smtjdd...

submitted 81 days ago • 0 comments

One of the alluring and theoretical strategies for extending healthspan and longevity is to rejuvenate the thymus gland, promote an intact immune system. Now there's a way to do that in aged mice. www.science.org/doi/10.1126/...

submitted 89 days ago • 9 comments

Thanks to @aruthak.bsky.social and colleagues for the invitation to this fantastic, unique meeting #multi-omics2024. Thnx for the shoutout to the awesome @martinalexsmith.bsky.social

submitted 88 days ago • 0 comments

When you get to be your own caricature!! Grateful to be in #oz sharing science with #friends. For those missing out #multiomics2024 is where #singlecell #spatial #omics #immunology #oncology and #precisionmedicine is where it’s at🥳

submitted 92 days ago • 2 comments

Yesterday, I presented our latest results mining single molecule m6A data at #multiomics2024: We see changes in m6A levels following CRISPR-cas13 knock-down of oncogenic lncRNAs that are independent of mRNA expression levels, revealing new dimensions of highly pertinent biological information

submitted 91 days ago • 0 comments

A nice explanation of the space our Cancer Ecosystems Program researchers work in - its tricky! but they are applying spatial and single cell multiomics to clinical samples and taking big steps forward towards better outcomes for patients - check out our team at www.garvan.org.au/research/str...

submitted 93 days ago • 0 comments

Public Service Announcement: Check colorblind-compatibility in Illustrator! Under 'View', 'Proof Setup' you can selected a colorblindness type to view your image in that spectra. Click 'Proof Colors' after to remove filter. We chose pink/green, yellow/blue here for accessibility (PMID 38112643).

submitted 98 days ago • 5 comments

Both #Cancer #Research starter packs are now completely full! ~300 researchers, oncologists, students, postdocs, patient advocates, and organizations supporting cancer research 🧪🔬⚕️ I hope you'll find these useful to build our community here Pack 1: go.bsky.app/FEoaJMc Pack 2: go.bsky.app/6EcjWNA

submitted 100 days ago • 32 comments

Truly brilliant work. Calling it a foundation model is a stretch (a mistake many people in the field make). But, the only single-cell AI model in its class that I think is worth the GPU energy expended and one that I excited to utilize. My stamp of approval. www.nature.com/articles/s41...

submitted 100 days ago • 0 comments

People deserve a world in which they can live in peace as themselves. What steps are people taking to ensure that in their communities, particularly as the world is going dark?

submitted 103 days ago • 0 comments

We are ramping up our attempts to get DC1 immunotherapy into the clinic for colorectal and lung cancer. Here me talk about why DC1s are the right choice, and how WEHI and PeterMacCC will get it to clinical trial within 2 yrs. Start ~13 min in. podcasts.apple.com/au/podcast/v...

submitted 103 days ago • 0 comments

Today I had the opportunity to present our ongoing translation of pan-LOX inhibitors in pancreatic cancer at the Australasian Gastrointestinal Trials Group (AGITG) Annual Scientific Meeting. Read more about this work here| → www.nature.com/articles/s43... ← |

submitted 103 days ago • 1 comment

This is incredible, thanks @deniswirtz.bsky.social

submitted 105 days ago • 0 comments

Too often we spend only two weeks choosing a problem and then many years trying solving it, but this limits our potential impact. A must read for PhD students: Problem choice and decision trees in science and engineering. pubmed.ncbi.nlm.nih.gov/38608651/

submitted 106 days ago • 6 comments

We recently released a new preprint on human localised prostate cancer biology. We used scRNA-Seq and spatial transcriptomics to dig deep into epithelial plasticity and stromal biology Led by Eva Apostolov www.biorxiv.org/content/10.1...

submitted 107 days ago • 0 comments