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alicekane.bsky.social
Ling/Obrzut Assistant Professor at the Institute for Systems Biology (ISB) in Seattle. Originally from Australia, now in the US. Interested in frailty, aging, epigenetics and mouse models.
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Check out our latest preprint on the development of clocks to predict PhenoAge in mice! www.biorxiv.org/content/10.1...

@susanehowlett.bsky.social Susan Howlett and I are co-editing a special issue of JGBS on Animal Models of Frailty πŸ’πŸΆπŸ­πŸ€ - reach out if you would like to contribute! academic.oup.com/biomedgeront...

Great work from the lab of @bbparis1984.bsky.social !

This Friday, 11:30-1 and in-person, @isbscience.org's @alicekane.bsky.social will present The Biology of Aging: Bridging Frailty and Health Outcomes, offering insights into how aging affects health & function. Register: www.eventbrite.com/e/2024-2025-...

Wondering if your study section cancelled? I update this sheet daily. As of today, 56/124 study sections that should have met since Jan 2, 2025 have "not met as scheduled." docs.google.com/spreadsheets...

Data request! Do you assess frailty index in your aging C57 mouse studies? @dantong-zhu.bsky.social is making new and improved clocks to predict age and lifespan based on frailty data & we aim to validate widely! Reach out if you want to collaborate πŸ€πŸ‘΅β° Especially if you have female data + lifespan!

Introducing "Metagenomic Estimation of Dietary Intake", or "MEDI": a data-driven approach to estimating dietary and nutritional intake from stool DNA πŸ’© - 🍌πŸ₯¦πŸŸπŸ₯©πŸ“ˆ See @cdiener.com's excellent thread below. We are really proud of this work, and we hope it is useful to the scientific community.

Happy to announce that MEDI, our method to quantify dietary intake through metagenomics is out now. 🧬 πŸ§ͺ🧫🦠 www.nature.com/articles/s42... #metagenomics #microbiome #microbiomesky So what is MEDI? A combination of two things:

Interested in doing a PhD in Austria focused on understanding how to engineer the composition of the gut microbiota? Want to work with a brilliant computational biologist and microbiome researcher? See below!

The Dog Aging Project is an innovative research initiative that brings together a community of dogs, owners, veterinarians, researchers, and volunteers to carry out the most ambitious canine health study in the world. dogagingproject.org

🌟 Join us in Anchorage, Alaska for the AGE 53rd Annual Meeting: New Frontiers in Aging Research! 🌟 This is an event you won’t want to miss! πŸ“… Save the Date & Be Part of the Conversation!

Metabolomics biomarkers of frailty: a longitudinal study of aging female and male mice "...In summary, our results identify sex-specific metabolite biomarkers of frailty in aging, and shed light on potential mechanisms involved in frailty" @alicekane.bsky.social www.biorxiv.org/content/10.1...

Biological sex is a key modifier of #aging phenotypes, including #Brain 🧠 aging. See this piece out today in #Neuron, spearheaded by @denadubal.bsky.social, co-authored by #YousinSuh, @ctmurphy1.bsky.social and myself on the topic: www.sciencedirect.com/science/arti... #GeroSky #SexDifferences

Check out the first publication from the Kane lab @isbscience.org! RNAseq analysis of sex differences in aging across tissues - spoiler alert - there are lots of them! bsd.biomedcentral.com/articles/10.... Congratulations and thans to @dantong-zhu.bsky.social, @judywbio.bsky.social & other authors.

Looking to hire a postdoc who is excited about epigenetics and aging! ISB is an incredible place to work, and Seattle is great! Plus Washington postdoc salaries are πŸ‘Œ Come join us! isbscience.hrmdirect.com/employment/j...