annagloyn.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

We link molecular and functional phenotypes of islet cells from donors with type 1 diabetes to understand impaired insulin and glucagon secretion. Immune signalling, nuclear exclusion, mTOR and lysosomes in alpha cell dysfunction. https://www.biorxiv.org/content/10.1101/2025.02.20.639325v1

submitted 7 days ago • 1 comment

Inter individual variability in the child and adolescent proteome is influenced by genetic variants, age, sex and body mass index @naturegenet.bsky.social #proteomics #genetics www.nature.com/articles/s41...

submitted 9 days ago • 0 comments

It was a pleasure for our team to be able to contribute to this manuscript on Vimentin+ alpha cells in CF 👇🏻 joe.bioscientifica.com/view/journal...

submitted 9 days ago • 0 comments

Super proud of Eliel Akinbami and the amazing work he is pioneering to understand how enzyme sequence encodes enzyme function!

submitted 16 days ago • 0 comments

This morning we stepped out of our normal routines to learn about our personality types and how they influence our leadership style. Check out with this amazing group of early career faculty! Thanks to Stevie Eberle from Stanford Bioscience Careers for an informative interactive session!

submitted 20 days ago • 0 comments

Was such a pleasure to listen to @drprentice.bsky.social deliver todays Frontiers seminar - beautiful science - presented with honest timeline on experiments, frustrations and eureka 💡 moments. A master class in how to follow your data and design experiments that deliver concrete answers … 🙌🙌🙌🙌

submitted 22 days ago • 0 comments

How are multiplexed assays of variant effect (MAVEs) transforming genetic variant curation? Dr. Douglas Fowler of IGVF joins the DNA Today podcast to discuss how MAVEs improve variant interpretation and are advancing precision medicine. 🎧 Listen now: dnatodaypodcast.podbean.com/e/325-revolu...

submitted 28 days ago • 0 comments

Mapping variant effects for a healthier future! Explore our 2024 #AnnualReport. From membership growth to global collaborations, discover how we're advancing genomics and making a difference #VariantEffectMapping www.varianteffect.org/annual-reports

submitted 26 days ago • 0 comments

Pre-print alert!! Did you know that exploration of loss and gain of eQTL regulation in normal versus disease condition from scRNAseq can reveal pos-transcriptional regulatory mechanisms (e.g. miRNA)? Have a look at our work, led by awesome @tdwinter.bsky.social, in which we focus on human islets.

submitted 32 days ago • 0 comments

The UKRN Dorothy Bishop Prize is open for nominations until midnight of Sunday 26 January 2025! www.ukrn.org/2024/12/12/t...

submitted 36 days ago • 0 comments

Because you're worth it www.forwomeninscience.com.au

submitted 35 days ago • 1 comment

Looking forward to reading this! It’s always great to see open-science supporting other researchers too!

submitted 35 days ago • 1 comment

Fantastic new work from @sethasharp and @annagloyn.bsky.social . T1D GRS for the clinic may be getting close !

submitted 36 days ago • 0 comments

Standardized Measurement of Type 1 Diabetes Polygenic Risk Across Multi-Ancestry Population Cohorts https://www.medrxiv.org/content/10.1101/2025.01.16.25320691v1

submitted 41 days ago • 0 comments

Want to generate #T1DGRS in your data or data from any biobank? @SethASharp has updated his #GRS2 originally developed with Richard alarm & Mike Weedon - code available on #GitHub Great collaboration with AmberMLuckett medrxiv.org/content/10.110… github.com/sethsh7/prsedm 👇👇👇

submitted 36 days ago • 1 comment

Today we shared the beta version of the shinny new #PanKbase platform with our #HIRN colleagues at the 10 ye anniversary meeting. Everything you want to know about the pancreas and diabetes coming to pankbase.org check it out and provide feedback - scan QR code 👇

submitted 45 days ago • 1 comment

Excited to have been involved in this: The utility of at home continuous glucose monitoring coupled with machine learning to predict metabolic subtypes. Study was led by Mike Synder & Tracey McLaughlin & championed by Ahmed Metwally. @natureportfolio.bsky.social www.nature.com/articles/s41...

submitted 66 days ago • 1 comment

🎄🎁🎉🥳 Festive Fun today in the Lab Meeting - new team swag and the annual holiday gift lottery game. Grateful for this amazing group of colleagues 🙏

submitted 71 days ago • 0 comments

My first time at the American Pancreas Association - these GI doctors know how to set up a great meeting! Fun to be out of my endocrine comfort zone and learn about its neighbour the exocrine pancreas

submitted 78 days ago • 0 comments

Decisions decisions - beach or Kyle Gaulton and open science pancreas platforms …… great job on making genomic and genetic data accessible - introducing the exocrine pancreas community to the endocrine world #APA #Maui

submitted 79 days ago • 0 comments

Posting your preprint on bluesky

submitted 81 days ago • 2 comments

Diabetes mellitus—Progress and opportunities in the evolving epidemic. Reposting our landmark recent review in @cellpress.bsky.social . 11 citations in 4 months! www.sciencedirect.com/science/arti...

submitted 90 days ago • 1 comment

New work! Wherein we (as in, the AVE ODIC working group) looked at clinical variant classification across genetic ancestry groups in gnomAD and AoU and what we found... is exactly what you might expect, after decades of Eurocentric research. But we also show there's a better way forward! 🧬🖥️

submitted 315 days ago • 2 comments

First week of the lab #adventcalendar - lots of festive fun finding locations for our daily funko pop arrivals … 19 doors left to open

submitted 83 days ago • 0 comments

Exciting study by Amanda Andersson Rolf et al: In vitro expansion of a human fetal #pancreas #stemcell that generates all three pancreatic cell lineages”. www.cell.com/cell/fulltex... New #organoid protocol allows the seemingly indefinite expansion of human fetal pancreatic Lgr5+ stem cell 1/

submitted 87 days ago • 1 comment

I’m not sure why or how they picked me but it does feel like a life achievement unlocked to have been a clue on Jeopardy!

submitted 86 days ago • 18 comments

Fantastic to see the state of California commit $9.25M over 4y to extend All of Us' engagement efforts throughout California allofus.nih.gov/news-events/...

submitted 86 days ago • 1 comment

Heterogeneous endocrine cell composition defines human islet functional phenotypes https://www.biorxiv.org/content/10.1101/2024.11.20.623809v1

submitted 98 days ago • 0 comments

Reminder for newcomers that bioRxiv has Bluesky accounts in every subject category - great way to keep up (please re-skeet) connect.biorxiv.org/news/2023/09...

submitted 110 days ago • 6 comments

Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”. doi.org/10.1038/s422... A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social

submitted 95 days ago • 6 comments

@annagloyn.bsky.social speaking on the genetics of diabetes at #dcan2024

submitted 97 days ago • 1 comment

📢 Listen in on "Expanding Human #Islet Research via the Integrated Islet Distribution Program (IIDP) Research Data Repository" with Dr. Joyce Niland and James Cravens presenting #dkNET LIVE webinar on Friday, Nov. 22, 2024, 11 AM PT! Register now 👇 dknet.org/about/blog/2790

submitted 98 days ago • 0 comments

Thanks @dgmacarthur.bsky.social I really loved science Twitter. I hope we can rebuild that here.

submitted 102 days ago • 1 comment

We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how: docs.bsky.app/docs/advance... #AcademicSky #HigherEd #Altmetrics

submitted 102 days ago • 176 comments

Jeeyeon Cha with the other keynote. Sex differences in islet biology! Introduced by the amazing Liz Rideout

submitted 105 days ago • 0 comments

#VDRD2024 Vancouver Diabetes Research Day on #worlddiabetesday

submitted 105 days ago • 1 comment

Keynote speaker Dr. Anna Gloyn kicking off our 11th Annual Vancouver Diabetes Research Day (VDRD) on Nov 14, World Diabetes Day, supported by the BC Diabetes Research Network

submitted 105 days ago • 2 comments

Check out the new and fully GDPR compliant Helmholtz Munich genotype imputation server! rdcu.be/d0h3y Server webpage: imputationserver.helmholtz-munich.de/index.html (don't think Ele Zeggini has joined bluesky yet but this is basically a cross-post from her twitter)

submitted 105 days ago • 0 comments