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apposada.bsky.social
Postdoctoral Fellow at Living Systems Institute (University of Exeter). Comparing regulation of gene expression in weird, oftentimes regenerative animals.
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Lungfish xkcd.com/3064

submitted 34 days ago • 99 comments

Y'all so excited to build this world lol

submitted 34 days ago • 2 comments

This. A thousand times this. "If the UK genuinely seeks to position itself as a global leader in academia and innovation, it must foster an environment that is welcoming to top talent."

submitted 35 days ago • 0 comments

🚨 New paper alert! 🚨 A robustly rooted tree of eukaryotes sheds light on their deep evolutionary ancestry—suggesting that the Last Eukaryotic Common Ancestor (LECA) may have had an excavate-like cell architecture. 🧵🔬 (1/) www.nature.com/articles/s41...

submitted 39 days ago • 5 comments

Ever wondered how sperm are formed? Spermatogenesis is a microscopic marathon that starts in the testes and ends with fully functional sperm! Our new preprint bitly.cx/jC4Qg takes a deep dive into zebrafish spermatogenesis, mapping out every fascinating step. 🧵👇 1/7

submitted 38 days ago • 2 comments

Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n

submitted 40 days ago • 56 comments

We’ve looked at snails with one shell and slugs with no shells. Now let’s have a look at a snail with two shells, because Nature laughs at our puny attempts to pigeonhole. In today’s #AtoZ – J is for Julia (Juliidae) (1/9) Pic: © uwkwaj CC BY-NC

submitted 42 days ago • 20 comments

Happy to present the peer-reviewed version of our Hydractinia Cell Atlas paper out today in Nature Communications! As I presented this back when we were in “that other” social network, let me recap the basic findings and revision items in this thread: www.nature.com/articles/s41...

submitted 48 days ago • 5 comments

Very glad of having been part of this fantastic collaboration now available at Nature Communications! congrats especially to @hrhorkan.bsky.social and @drsalamander.bsky.social !! www.nature.com/articles/s41...

submitted 48 days ago • 1 comment

The version of record is out in eLIFE - elifesciences.org/articles/92683 - the hard work of Mayalen Etcheverry, Clement Moulin-Frier, and @pyoudeyer.bsky.social as we try to develop tools to characterize the behavior space of gene-regulatory networks (and pathways more broadly)

submitted 97 days ago • 0 comments

This will be a wonderful conference - come discuss the origin of metazoans and enjoy fruits de mer with us in Roscoff!

submitted 102 days ago • 0 comments

Good piece by @natureportfolio.bsky.social. The erosion of thinking time—driven by admin, bureaucracy, industry agendas, and unrealistic output targets—stifles curiosity-led science. These pressures undermine innovation and the intellectual freedom vital for real progress. 🧪🌱🌍 #ScienceIsNotBusiness

submitted 115 days ago • 14 comments

🍾Our small #UExM adventure is only starting! #ProtistsOnSky We are happy to announce that the Moore Foundation will be funding our efforts in creating an Expansion Microscopy atlas of #Microbial #Eukaryotes with @gautamdey.bsky.social @UNIGE @embl.org LINK: www.unige.ch/sciences/chi... 1/4

submitted 123 days ago • 12 comments

Also I'm happy I finally managed to download what for a while was the only dataset of cell cycle gene expression in mouse (fibroblasts), from back in 2001. This had been previously inaccessible but I guess there's now a copy in archive.org? The 2019 version of me is happy and can finally rest.

submitted 120 days ago • 0 comments

Re-reading the introduction of my PhD thesis, which I defended 5 years ago (time flies...). Trying to find some inspiration for writing new proposals, and I'm surprised why I never bothered to submit it as a bibliographical review somewhere. ... I might do it at some point I think.

submitted 120 days ago • 0 comments

I think most of it is inhabiting the data.. if you are really trying to get a full understanding of a mechanism, then every piece of data either fits or doesn't fit.. it's always trying to live inside the data and use it to test the structure. – Ellen Rothenberg

submitted 122 days ago • 1 comment

"[...]pluripotent cells as cells in a “high-temperature” state. In fact, they should be able to freely navigate the landscape, only to become progressively con strained into a specific valley when they commit to a differentiation path. [...]" www.biorxiv.org/content/10.1...

submitted 128 days ago • 0 comments

“Acanthocystis turfacea with ingested rotifer” From the beautiful Hudson transparency collection at the University of Exeter. specialcollectionsarchive.exeter.ac.uk/collections/...

submitted 133 days ago • 0 comments

Honored and excited to receive an #ERCCoG grant. Big thanks to my colleagues, former mentors and, most importantly, my amazing lab members. Together, we will be exploring cell type evolution across timescales, from population variation (with @xgrau.bsky.social) to regulatory sequences across phyla.

submitted 138 days ago • 31 comments

SOX and POU are crucial Transcription Factors in animal development, believed to be innovations of this group. Here we find them in unicellular relatives of animals. And hold tight, you can use a choanoflagellate 🦠 SOX gene to make a full chimeric 🐁 ! Read more here 🧵: rdcu.be/d0dPN 1/6

submitted 157 days ago • 13 comments

🚨 The Colorado Index of Complex Networks (icon.colorado.edu) is reborn! ICON 2.0 indexes 699 distinct research-quality network data sets, classified into 6 domains (Social, Biological, Information, Economic, Technology, Transportation) and 53 subdomains /1 #networkscience

submitted 160 days ago • 1 comment