barnabalab.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Thanks @franbottanelli.bsky.social for leading this effort! Addition genome editing plasmids are available on our labs addgene page. www.addgene.org/Jens_Schmidt/

submitted 3 days ago • 0 comments

Long in the making but our protocol for gene editing is online! FAB CRISPR is super easy and allows the generation of N and C terminal fusions with TurboID, SNAP, Halo and mStayGold. A single cloninf step to generate HDR templates! arxiv.org/abs/2502.12675 1/n

submitted 3 days ago • 3 comments

Looks like we're back teaching chemistry...😎

submitted 4 days ago • 0 comments

Happy to announce that MEDI, our method to quantify dietary intake through metagenomics is out now. 🧬 🧪🧫🦠 www.nature.com/articles/s42... #metagenomics #microbiome #microbiomesky So what is MEDI? A combination of two things:

submitted 4 days ago • 1 comment

🔬🎤 As pre-announced a few days ago... please let us proudly present to you: 𝑴𝒊𝒄𝒓𝒐𝕊𝒑𝒍𝒊𝒕 - your ticket to imaging more, imaging more gentle, and/or imaging more efficient. 🔬 doi.org/10.1101/2025... Like ❤️, repost 🔂, and most importantly... please send feedback ✉️ our way! 🙏

submitted 11 days ago • 2 comments

Excited to share a new paper from our lab 😀 We investigate the tumor microenvironment - to reveal factors influencing cancer progression & therapy response 🔬🧪 So we naturally wanted to ask - does the gut #microbiome influence brain #metastasis 🦠 🧠? Massara et al 2025 www.cell.com/iscience/ful...

submitted 12 days ago • 4 comments

Bastante flipantes siempre los datos de España e Italia

submitted 19 days ago • 0 comments

Reposting this. The #postdoc position in my laboratory at KU-School of Pharmacy is still open until 2.9.25. Please apply if you have experience in proteomics and want to work in P450 drug metabolism. #hiring

submitted 23 days ago • 0 comments

Indeed impressive work.

submitted 24 days ago • 0 comments

Integrated the red laser and a camera into an OPM light-sheet system that can now do simultaneously TIRF and 3D imaging. Seems to work. Shown is the BSI prime camera for TIRF imaging.

submitted 24 days ago • 0 comments

I was not aware of the passing of the legendary Prof. James Kincaid at Marquette University. His groundbreaking work on cytochrome P450 spectroscopy, especially his seminal collaboration with Prof. Sligar, was a must-read during my grad school. www.sciencedirect.com/science/arti...

submitted 24 days ago • 0 comments

Did you know the NIH hosts a 3D printed lab hardware repository? Looking forward to uploading stuff there too. Go check it out! 3d.nih.gov

submitted 24 days ago • 7 comments

🧵Prepint alert! Optimizing Multifunctional Fluorescent Ligands for Intracellular Labeling | tinyurl.com/3n55hvsc. With Jason Vevea, Ed Chapman, and @so-lets-kilab70.bsky.social, we combined dye chemistry, HaloTag, microscopy and cell biology to make protein purification and manipulation tools.

submitted 25 days ago • 2 comments

Great piece by @statfourwork.bsky.social "Should a university be based on a model in which researchers are only valued for their revenue-generating potential, or do we still have any reverence for the pursuit of knowledge that is not obviously translational or even (gasp) fundable?"🧪

submitted 28 days ago • 4 comments

Here is an important read from an important journal ! To quote @davidsdickens.bsky.social from his earlier post, the authors "highlight several pioneering strategies that show promise for safely bypassing this barrier." #BloodBrainBarrier #cerebrovascular www.thelancet.com/journals/lan...

submitted 28 days ago • 0 comments

More than 40 percent of #postdocs leave academia. Those who landed a coveted faculty position were more likely to have had a highly cited paper, changed their research topic between their #PhD and postdoc, or moved abroad after receiving their doctorate. www.pnas.org/doi/10.1073/... @pnas.org

submitted 30 days ago • 6 comments

#Hiring! The postdoctoral position in my lab at Pharm Chem KU is open!! This is an NIH-funded position to work on cytochrome P450 metabolism using a combination of mass spectrometry proteomics and live-cell imaging. employment.ku.edu/staff/29681BR

submitted 30 days ago • 1 comment

The PI right now in his office, managing his lab from Slack...

submitted 37 days ago • 2 comments

Did you know that many Europeans & descendants died a horrible death of pellagra (niacin deficiency) because maize was traded as a worldwide comestible staple without its indigenous preparation procedure? 🧪 Public health later decreed fortified flour to save lives. www.epicurious.com/ingredients/...

submitted 42 days ago • 2 comments

NEW: 2024 has just been confirmed as the warmest year on record, and the first to breach the 1.5C threshold. We used a ridgeline (Joy Division inspired) chart to visualise daily temperature anomalies since 1940. 2024 clearly stands out with 100% of its days above 1.3C and 75% above 1.5C.

submitted 43 days ago • 221 comments

💥 Exciting news! 💥 Our R35 MIRA grant from the NIGMS has been selected for funding 😎. Yay! This grant will fund our (young) lab for the next 5 years and push our research in metabolic adaptation forward. It also means that...we will be hiring! 😁

submitted 79 days ago • 1 comment

The dark side of fluorescent protein tagging: the impact of protein tags on biomolecular condensation www.biorxiv.org/content/10.1...

submitted 89 days ago • 10 comments

People of Bluesky! Quote a favorite film using gifs only.

submitted 94 days ago • 0 comments

Hi there! The Dept. of Pharmaceutical Chemistry at KU is hosting a Q&A webinar for aspiring grad students. Besides being a top school, we have state-of-the-art facilities and are extremely successful in placing our graduates in the pharma industry. Reposts appreciated :)

submitted 94 days ago • 1 comment

👇👇👇👇

submitted 96 days ago • 0 comments

¿Alguna vez te han preguntado: '¿y para qué sirve lo que estudiaste?' Bajo la lógica capitalista, todo debe tener un valor utilitario para justificar su existencia, pero esa no necesariamente es la verdad. Recomiendo mucho este libro que plantea la 'inutilidad' como una forma de resistencia humana.

submitted 97 days ago • 1 comment

How do I look for starter packs?!?

submitted 98 days ago • 1 comment

Hello Bluesky! The Barnaba Lab at KU-PharmChem works in metabolic adaptation, i.e. how our cells rewire their metabolism in response to chemical and nutrient stress. We’re a very young group, and we hope to make an impact in the broader scientific and non-scientific communities 😊 #rockchalkjayhawks

submitted 99 days ago • 0 comments