Profile avatar
bioetry.bsky.social
Emergence and evolution of bacterial pathogens. Complexity in biological systems. Dept. of Host-Microbe Interactions at St. Jude Children's Research Hospital. NSF CAREER. BWF PATH.
109 posts 2,959 followers 740 following
Prolific Poster
Conversation Starter

238 Kb genome! 😳

I have exhorted others to share positive news even in these uncertain times for US science. I am really excited that @tamanash.bsky.social’s first paper on the remarkable evolutionary gymnastics of dual-host viruses (even in single codons) is now online. Follow along here 🧪🧵

Did you know that there is so much DNA packed inside a phage capsid that the pressure is 10X higher than in a bottle of champagne? In our latest preprint, we wondered how that is contained in a phage that lives at extremely high temperatures. /1 www.biorxiv.org/content/10.1...

I love microbiology sooo much!

Come and work with me! The Nature Micro team is expanding and we're looking for someone to champion microbial ecology, plant micro & related areas for the journal Knowledge of microbial ecology/plant micro is desirable but we're open to applications from all microbiologists Link below 👇

Our latest paper, in which @brinda.eu (along with @zaminiqbal.bsky.social and others) introduces phylogenetic compression for storage and search of enormous microbial genome libraries, was published today in @naturemethods.bsky.social: rdcu.be/eg4OA 1/

I'm delighted to share a useful FREE web-based app portal of powerful bioinformatics tools for microbial genomes and shotgun microbiome sequences! It's called Micromics and is built by Middle Author Bioinformatics, led by co-founder @ironark.bsky.social omix.midauthorbio.com

Delighted to share that @asm.org has met its goal for all of its 'legacy' journals (ie favorites like J. Bact, I&I, AEM) so ALL 2025 articles will be published open access. Thanks to all institutional subscribers, this is the S2O way. Please submit to these great journals! asm.org/Press-Releas...

Thrilled to share our @elife.bsky.social paper "Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages" by 1st author Dr. @marisaegan.bsky.social (@cambupenn.bsky.social alum, now faculty @swarthmorecollege.bsky.social)! elifesciences.org/articles/90107 🧵(1/n)

Awwww yeah, check this out: snowflake yeast making their cover debut! www.nature.com/nature/volum... We have two papers in this issue: 1) A paper examining whole genome duplication in the MuLTEE 2) A review of long-term experiments in evolutionary biology led by @jameststroud.bsky.social 🧪

Gordon Research Conference - Marine Microbes, June 7 - 12, 2026. Barcelona, Spain www.grc.org/marine-micro...

Our Tn-seq paper is out in PLOS Genetics! @plos.org We found a new Vibrio chitoporin and a key regulator of chitinolytic growth. Lots of other cool stuff too! Great work by Oriana Robinson and @landongetz.bsky.social journals.plos.org/plosgenetics...

www.nature.com/articles/s41... In collaboration with Andrew Lang and Alison Buchan, we just published a review on the complex and sometimes convoluted interactions and evolutionary relationships among bacterial mobile genetic elements. #phage #plasmid #evolution #bacteria #plasmidbiology #MGE

If you are around Philly/Penn next week (March 19-20), I encourage you to attend the Institute for Infectious Zoonotic Diseases Symposium. Can't wait to present our work on pathogen emergence and hear the keynote by no other than Dr. Peter Hotez!! www.vet.upenn.edu/research/cen...

Imagine this: The same young scientists now trying to get into PhD programs, facing reduced admissions and uncertainty over whether labs can take them on due to NIH funding cuts, also survived high school during peak COVID and navigated college through a pandemic. 😥😒 #standupforscience

Antibiotics from Australian Oyster blood??? The fight against #AMR is leading to some strange places www.medscape.com/viewarticle/...

1/2 New publication from the lab from the talented postdoc Dr. Andy Perrault in collaboration with Dr. Alejandro Pironti! pubmed.ncbi.nlm.nih.gov/39977318/

Iconic jazz album covers Please add some more….. #thejazzworld #jazzsky #Music #jazz

Legitmately thrilled to share our latest work, in which @fernpizza.bsky.social solved an experimental challenge in plasmid biology as old as the field: measuring how plasmids compete and evolve within individual cells!

Experimental evolution of evolvability | Science www.science.org/doi/10.1126/...

This is a renaming I can go along with 😎

Our Evolution of Evolvability work is finally* out! *technically it has been out for a bit, but all of ~this~ bullshit was happening www.pnas.org/doi/abs/10.1...

Delighted to share our new study. A collaboration with the Thurlow lab. Antibiotic resistance rapidly emerges and thrives in diabetic mice. A worrying coming together of two major and growing health problems worldwide www.science.org/doi/10.1126/...

Gram-neg bacteria can resist #phages by modifying their LPS, also affecting #antibiotic susceptibility. @lavishaparab.bsky.social &co show that antibiotic concentrations influence evolution of E. coli phage resistance, leading to enhanced phage-antibiotic synergy 🧪 @plosbiology.org plos.io/4hPmO0X

I am confident that scientific societies will play an unusually important role in the coming years. If you are a microbiologist of any kind, please consider joining @asm.org if you haven't already. There are many ways to get involved, including advocacy. To learn more: asm.org/About-ASM/Vo...

Why don't HUMANS have proper WHISKERS like most other mammals? We are, in fact, one of only a handful of mammals that DON'T have whiskers ('vibrissae'): it's us, rhinos, some whales, dolphins & apes. Even most aquatic mammals have them. First, we need to understand how they work... (📷: Salix)

Congrats to @vscooper.micropopbio.org, Joanna Goldberg and @copperbae.bsky.social for their election as next President and At-Large Board Directors of @asm.org! Our beloved Society is in great hands!

Which of these four album is your favorite? #thejazzworld #jazzsky #Music #jazz

🚨 We also have a "Scientist" position in my lab at St. Jude. The position is financially stable and with a very competitive salary range. 📝 If you have Postdoctoral experience and want to develop a steady research career this one is for you! ➡️ Apply here: talent.stjude.org/careers/jobs...

I'm very happy to report that Matt Schechter's PhD work is now online as a pre-print: "Ribosomal protein phylogeography offers quantitative insights into the efficacy of genome-resolved surveys of microbial communities", www.biorxiv.org/content/10.1... Here's a little 🧵 about it.

Wonderful review about the relationship between global environmental changes and infectious disease dynamics! www.nature.com/articles/s44...

🚨 We have an "Associate Scientist" position in my lab at St. Jude. The position is financially stable and with a very competitive salary range. 📝 If you have a PhD and want to develop a steady research career this position is for you! ♻ Please RT stjude.wd1.myworkdayjobs.com/stjude/job/M...

And the move is now complete! Wohooo!

1/ 🔬 Our work, "Dynamic transitions of initiator binding coordinate the replication of the two chromosomes in Vibrio cholerae", is now published in Nature Communications. Here's a thread on how we think Chr1 and Chr2 replication is coordinated in Vibrio. 🧵 Link : www.nature.com/articles/s41...

It’s “Science Christmas” for the Moreno Lab at St. Jude. Looking forward to setting things up!

The 22nd European Workshop on Bacterial Protein Toxins, ETOX 2025, will be held in Spain, June 29 - July 3, 2025. Registration opens tomorrow. Apply here etox-meetings.org and join us for a great meeting!

New paper alert: Our 20-year study of viral ecology and evolution reveals viral roles in microbial dynamics, phage genome evolution over time, and key interactions with hosts. A big thank you to our awesome collaborators @quendi.bsky.social @archaeal.bsky.social www.nature.com/articles/s41...