biorxiv-biophys.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

An engineered platform to study the influence of extracellular matrix nanotopography on cell ultrastructure https://www.biorxiv.org/content/10.1101/2025.02.27.640302v1

submitted 2 hours ago • 0 comments

Brightness demixing for simultaneous multi-target imaging in 3D single-molecule localization microscopy https://www.biorxiv.org/content/10.1101/2025.03.02.639924v1

submitted 3 hours ago • 0 comments

Cryo-ET of IgG bivalent binding on SARS-CoV-2 provides structural basis for antibody avidity https://www.biorxiv.org/content/10.1101/2025.02.28.640788v1

submitted 22 hours ago • 0 comments

A multiscale theory for mesenchymal cell migration in straight or curved channel confinement https://www.biorxiv.org/content/10.1101/2025.02.26.640464v1

submitted 1 day ago • 0 comments

Sequence-dependent shape and stiffness of DNA and RNA double helices: hexanucleotide scale and beyond https://www.biorxiv.org/content/10.1101/2025.02.27.640607v1

submitted 1 day ago • 0 comments

Continuum theory for the mechanics of curved epithelial shells by coarse-graining an ensemble of active gel cellular surfaces https://www.biorxiv.org/content/10.1101/2025.02.27.640501v1

submitted 1 day ago • 0 comments

Tubulin transforms Tau and -synuclein condensates from pathological to physiological https://www.biorxiv.org/content/10.1101/2025.02.27.640500v1

submitted 1 day ago • 0 comments

Coarse-grained chromatin dynamics by trackingmultiple similarly labeled gene loci https://www.biorxiv.org/content/10.1101/2025.02.27.640402v1

submitted 1 day ago • 0 comments

DeepPath: Overcoming data scarcity for protein transition pathway prediction using physics-based deep learning https://www.biorxiv.org/content/10.1101/2025.02.27.640693v1

submitted 1 day ago • 0 comments

A model of protein folding with multiple native states:Metamorphicity, Intrinsic disorderness and folding uponbinding of proteins https://www.biorxiv.org/content/10.1101/2025.02.26.640301v1

submitted 1 day ago • 0 comments

2Danalysis: A toolbox for analysis of lipid membranes and biopolymers in two-dimensional space https://www.biorxiv.org/content/10.1101/2025.02.27.640563v1

submitted 1 day ago • 0 comments

Lipids Are Involved in Heterochromatin Condensation: A Quantitative Raman and Brillouin Microscopy Study https://www.biorxiv.org/content/10.1101/2025.02.26.640449v1

submitted 1 day ago • 0 comments

Structure of far-red allophycocyanin: stripped down and tuned up for low energy photosynthesis. https://www.biorxiv.org/content/10.1101/2025.02.25.640088v1

submitted 1 day ago • 0 comments

Deconvolution to restore cryo-EM maps with anisotropic resolution https://www.biorxiv.org/content/10.1101/2025.02.23.639707v1

submitted 2 days ago • 0 comments

Osmotic pressure induces unexpected relaxation of contractile 3D microtissue https://www.biorxiv.org/content/10.1101/2025.02.25.640067v1

submitted 2 days ago • 0 comments

CADENCE: Clustering Algorithm - Density-based Exploration and Novelty Clustering with Efficiency https://www.biorxiv.org/content/10.1101/2025.02.24.639863v1

submitted 3 days ago • 0 comments

Lipid-mediated mechanism of drug extrusion by a heterodimeric ABC exporter https://www.biorxiv.org/content/10.1101/2025.02.26.640354v1

submitted 3 days ago • 0 comments

Mechanism of giant magnetic field effect in fluorescence of mScarlet3, a red fluorescent protein https://www.biorxiv.org/content/10.1101/2025.02.26.640351v1

submitted 3 days ago • 0 comments

Calcium stabilization of a flexible N-terminal domain in a pentameric ligand-gated ion channel https://www.biorxiv.org/content/10.1101/2025.02.24.640012v1

submitted 3 days ago • 0 comments

Exploration of the influence of environmental changes on the conformational and amyloidogenic landscapes of the zinc finger protein DPF3a by combining biophysical and molecular dynamics approaches https://www.biorxiv.org/content/10.1101/2025.02.24.640013v1

submitted 3 days ago • 0 comments

Electrokinetic detection of single-molecule phosphorylation https://www.biorxiv.org/content/10.1101/2025.02.24.640009v1

submitted 3 days ago • 0 comments

Fast-tracking native mass spectrometry: Skipping over buffer exchange https://www.biorxiv.org/content/10.1101/2025.02.22.639503v1

submitted 3 days ago • 0 comments

Hydrodynamic Radius Determination of Tau and AT8 Phosphorylated Tau Mutants: A Combined Simulation and Experimental Study https://www.biorxiv.org/content/10.1101/2025.02.22.639620v1

submitted 3 days ago • 0 comments

Orthosteric interactions with PIP2 activate TMEM16A channels https://www.biorxiv.org/content/10.1101/2025.02.24.639951v1

submitted 3 days ago • 0 comments

A database for large-scale docking and experimental results https://www.biorxiv.org/content/10.1101/2025.02.25.639879v1

submitted 3 days ago • 0 comments

The keratin cortex stabilizes cells at high strains https://www.biorxiv.org/content/10.1101/2025.02.24.639846v1

submitted 3 days ago • 0 comments

Structure and dynamics of a multidomain ligand-gated ion channel revealed under acidic conditions https://www.biorxiv.org/content/10.1101/2025.02.27.640520v1

submitted 3 days ago • 0 comments

Linker histone H1.0 loads onto nucleosomes through multiple pathways that are facilitated by histone chaperones https://www.biorxiv.org/content/10.1101/2025.02.23.639383v1

submitted 3 days ago • 0 comments

LivecellX: A Deep-learning-based, Single-Cell Object-Oriented Framework for Quantitative Analysis in Live-Cell Imaging https://www.biorxiv.org/content/10.1101/2025.02.23.639532v1

submitted 3 days ago • 0 comments

High-Throughput Centrifuge Force Microscopy Reveals Dynamic Immune-Cell Avidity at the Single-Cell Level https://www.biorxiv.org/content/10.1101/2025.02.27.640408v1

submitted 3 days ago • 0 comments

Helical foldamers as selective G-quadruplex ligands https://www.biorxiv.org/content/10.1101/2025.02.25.640101v1

submitted 3 days ago • 0 comments

Theoretical Analysis of Power-Law Stress Relaxation and Calcium-Dependent Passive Mechanics in Cardiac Muscle https://www.biorxiv.org/content/10.1101/2025.02.26.640338v1

submitted 3 days ago • 0 comments

Distinct Clinical Phenotypes in KIF1A-Associated Neurological Disorders Result from Different Amino Acid Substitutions at the Same Residue in KIF1A https://www.biorxiv.org/content/10.1101/2025.02.26.640415v1

submitted 3 days ago • 0 comments

Ca2+ increases cardiac muscle viscoelasticity independent of active force development https://www.biorxiv.org/content/10.1101/2025.02.26.640328v1

submitted 3 days ago • 0 comments

Nanometer condensate organization in live cells derived from partitioning measurements https://www.biorxiv.org/content/10.1101/2025.02.26.640428v1

submitted 3 days ago • 0 comments

Deciphering the Molecular Mechanisms of BPTF Interactions with Nucleosomes via Molecular Simulations https://www.biorxiv.org/content/10.1101/2025.02.25.640153v1

submitted 3 days ago • 0 comments

Nuclear speckle proteins form intrinsic and MALAT1-dependent microphases https://www.biorxiv.org/content/10.1101/2025.02.26.640430v1

submitted 4 days ago • 0 comments

Compositional control of ageing kineticsin TDP-43 condensates https://www.biorxiv.org/content/10.1101/2025.02.21.639421v1

submitted 4 days ago • 0 comments

OpenCafeMol: A GPU-accelerated coarse-grained biomoleculardynamics simulator with OpenMM library https://www.biorxiv.org/content/10.1101/2025.02.20.639390v1

submitted 4 days ago • 0 comments

Spatial self-organization of confined bacterial suspensions https://www.biorxiv.org/content/10.1101/2025.02.20.639202v1

submitted 4 days ago • 0 comments

Experimental Evidence for Phosphorylation-Driven Allosteric Regulation of Alpha Synuclein Function https://www.biorxiv.org/content/10.1101/2025.02.20.639338v1

submitted 4 days ago • 0 comments

Mechanical strain modulates Min patterning and division in E. coli filaments https://www.biorxiv.org/content/10.1101/2025.02.21.638242v1

submitted 4 days ago • 0 comments

The Critical Role of the 2'-OH group in Phase Separation and Percolation Transitions of RNA https://www.biorxiv.org/content/10.1101/2025.02.26.638501v1

submitted 4 days ago • 0 comments

Experimental and theoretical approaches reveal that antimicrobial blue light killing efficiency decreases with biofilm growth in a Pseudomonas aeruginosa model. https://www.biorxiv.org/content/10.1101/2025.02.26.636652v1

submitted 4 days ago • 0 comments

Electrostatics facilitate mid-air host attachment in parasitic jumping nematodes https://www.biorxiv.org/content/10.1101/2025.02.20.639345v1

submitted 5 days ago • 0 comments

Single-molecule observation of multi-scale dynamic heterogeneity in the molecular bearing of the bacterial flagellum https://www.biorxiv.org/content/10.1101/2025.02.20.639300v1

submitted 5 days ago • 0 comments

Structural Plasticity of RRE Stem-Loop II Modulates Nuclear Export of HIV-1 RNA https://www.biorxiv.org/content/10.1101/2025.02.20.639096v1

submitted 5 days ago • 0 comments

Combining MicroED and native mass spectrometry for structural discovery of enzyme-biosynthetic inhibitor complexes https://www.biorxiv.org/content/10.1101/2025.02.20.638743v1

submitted 5 days ago • 0 comments

Bilayer-forming lipids enhance archaeal monolayer membrane stability https://www.biorxiv.org/content/10.1101/2025.02.20.639260v1

submitted 5 days ago • 0 comments

Analysing diffusion limited processes in a cylinder using pair-correlation functions https://www.biorxiv.org/content/10.1101/2025.02.19.639196v1

submitted 5 days ago • 0 comments