brettcollins.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

I have exhorted others to share positive news even in these uncertain times for US science. I am really excited that @tamanash.bsky.social’s first paper on the remarkable evolutionary gymnastics of dual-host viruses (even in single codons) is now online. Follow along here 🧪🧵

submitted 3 hours ago • 2 comments

In autumn 2024, David Stephens, a brilliant scientist, leader and mentor, passed away. @jondlane.bsky.social and George Banting reflect on David’s immense contributions to the scientific community, including his role as JCS Editor. journals.biologists.com/jcs/article/...

submitted 1 day ago • 0 comments

Stunning photo of Mars on the cover of Science this week! And super proud that our structure of PINK1 stalled at mitochondrial translocases also gets a cover mention 😊. It's now out in print on page 303!

submitted 20 hours ago • 0 comments

Our PhD student Louis Romette is optimizing long-term live-cell imaging. He just casually dropped this 65-hour movie of a growing neuron (div 3 to 6) with knocked-in actin 🔥🕶️ #realtimemicroscopy

submitted 1 day ago • 13 comments

“It’s amazing that others in this room underwrote electing a man who, in the last week, single-handedly destroyed all of American science. It’s amazing how much good science you can destroy with $320 million and RFK Jr, very fast.” — Seth Rogen’s censored remarks presenting the Breakthrough Prize

submitted 2 days ago • 267 comments

Inbox: Australian Sex Discrimination Commissioner responds to UK supreme court ruling on trans women with support

submitted 1 day ago • 5 comments

Hurray, it is finally out! Meet bacteriophage Bxb1 - the subject of my first full-phage cryo-EM study. My structures are beautifully complemented by the Park Lab’s cryo-ET analysis, shedding light on mycobacteriophage structural changes during infection. www.sciencedirect.com/science/arti...

submitted 2 days ago • 3 comments

Seth Rogen’s remarks about destruction of US science cut from Breakthrough Prize video www.hollywoodreporter.com/news/general...

submitted 2 days ago • 0 comments

Meanwhile, CryoEM continues to make strides: here, the swinging lever mechanism of the actinomysin power stroke is resolved in atomic- and time-resolved detail, via a myosin-5 mutant with slow hyrdolysis product release. Some very awesome single molecule biophysics! www.nature.com/articles/s41...

submitted 2 days ago • 0 comments

Pleased to see Kevin's paper on the Retromer complex interaction with yeast Vps5 and Vps17 proteins now online!

submitted 3 days ago • 2 comments

No, Steve, I will not give you any more beer money. And no, I will not fight you for it, you're an Otter.

submitted 3 days ago • 19 comments

Abstract submissions for short talks are still opened until April 20th for the EMBO Escrt meeting 2025. There are plenty of options for short talks, please apply online at meetings.embo.org/event/25-escrt

submitted 4 days ago • 0 comments

"The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage" out now in Nature Cell Biology rdcu.be/ehbaL

submitted 8 days ago • 0 comments

Naoki Tomita et al.: Crystallization and initial X-ray crystallographic analysis of a de novo-designed protein with left-handed βαβ units #DeNovoProteinDesign #LeftHandedBetaAlphaBetaMotif #AlphaFold ... #IUCr https://journals.iucr.org/paper?S2053230X25003097

submitted 4 days ago • 0 comments

Nice

submitted 4 days ago • 0 comments

When you try to act grateful, but you've actually got lots of pebbles at home already.

submitted 4 days ago • 14 comments

Obviously things have got dramatically worse in the US recently, and I don't want to diminish that, but I've been at so many conferences in the UK on topics like empire, humanitarianism and development where multiple speakers from the Global South have been denied visas or held at the border

submitted 4 days ago • 40 comments

aside: a stunning comment from David Baker, UW professor who won the Nobel Prize in 2024. Now 15 lab members are looking for positions overseas. “There’s so many amazing people who want to come in, & we can’t take them. The Nobel Prize was just a little blip. But things have gotten quite bleak.”

submitted 4 days ago • 41 comments

A purrfectly normal envelope to have slid under my office door as a Crystallographer.

submitted 4 days ago • 1 comment

This is how your email finds me #catsOfAcademia #AustralianMist

submitted 4 days ago • 0 comments

Turns out by saying this, I get deemed a collaborator. No matter how much as an out member of the LGBTQ+ community, I express support for young queer people, especially in science.

submitted 4 days ago • 6 comments

Beautiful CryoET of mitochondrial respiratory chain (from a rather acute angle!) by @cellarchlab.com at #EMBOclimateResilience

submitted 4 days ago • 1 comment

I feel seen...

submitted 5 days ago • 11 comments

I am a professor at Columbia University. All of the student NIH training grants have been canceled and now there are reports that ALL funding will be frozen. Why are Universities not banding together and speaking out publicly and forcibly about governmental attacks on biomedical research?

submitted 7 days ago • 58 comments

Rainy Saturday grant writing #CatsOfAcademia ARC ruining #schoolHolidays again 😤

submitted 6 days ago • 3 comments

Did you know… It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳 For details, visit our website: journals.biologists.com/jcs/pages/re...

submitted 9 days ago • 1 comment

submitted 7 days ago • 308 comments

Spotlight: Yan Zhao previews work from Qiming Sun and colleagues (rupress.org/jcb/article/...), which shows how Rab #GTPases serve as cues for cargo receptor recruitment, mediating #mitophagy, #lipophagy, and #xenophagy. rupress.org/jcb/article/... #autophagy

submitted 8 days ago • 1 comment

The University of Queensland is recruiting for a new Director to play a pivotal role in shaping neuroscience research in Queensland and beyond. Closing date: 19th May www.dementiaresearcher.nihr.ac.uk/job/director...

submitted 7 days ago • 1 comment

www.nature.com/articles/d41...

submitted 7 days ago • 0 comments

Here our new preprint on the LPS holo-translocon doi.org/10.1101/2025... , collaboration with Yves Quentin @JulieMarcoux @fronzeslab.bsky.social @pstansfeld.bsky.social - @cbitoulouse.bsky.social

submitted 7 days ago • 1 comment

Marino Zerial, director at @humantechnopole.bsky.social and @mpi-cbg.de received his certificate as new member of the Leopoldina on April 9th in Halle (Saale). 🎉 The event also featured the Leopoldina Life Science Symposium on April 10, where Marino gave a talk. Photo: Anna Kolata | Leopoldina

submitted 7 days ago • 0 comments

For our latest paper, we worked with SYROS Pharmaceuticals, the groups of Dylan Taatjes and Robin Dowell at CU Boulder, and @abhaykot.bsky.social. Junjie Feng in my lab determined the #cryoEM structure of the CDK7 inhibitor SY5609 bound to its target... www.science.org/doi/10.1126/...

submitted 49 days ago • 5 comments

Good morning, everyone! I spy the weekend!!!

submitted 7 days ago • 10 comments

BREAKING: The country of Norway just entered a bill to give transgender Americans asylum in the country of Norway… LGBTQ+ STRONG! 🌈✨

submitted 8 days ago • 1053 comments

In case you’re trying to submit your response to the review of ARC grants, the Education Department’s portal is/was borked. Email instead👇

submitted 7 days ago • 0 comments

Take a deep breath and look at these otters relaxing. You probably need it.

submitted 8 days ago • 479 comments

‘Mountain of small things’ killing academia, warns Oxford scholar Overly cautious institutions pushing ‘bullshit jobs’ on their staff ‘destroying academia from within’, says neuroscientist www.timeshighereducation.com/news/mountai...

submitted 8 days ago • 1 comment

Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.” A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world. www.cnn.com/2025/04/09/h...

submitted 9 days ago • 15 comments

@jcb.org's April issue is here! rupress.org/jcb/issue/22... The cover shows a segmented model of cytoplasmic #ribosomes associated with mitochondrial membrane in a Saccharomyces cerevisiae cell. From Ya-Ting Chang, @nanigrotjahn.bsky.social and colleagues (doi.org/10.1083/jcb....)

submitted 11 days ago • 0 comments

If you want to find solutions you need to understand the underlying causes. Where is the data that international students are a major cause of the housing crisis? We're denying ourselves $ income and the chance to make good, long term friends in the region.

submitted 10 days ago • 2 comments

How do cytosol-invading bacteria evade LPS ubiquitylation by the host's defence machinery? @felixrandow.bsky.social's group determined that Shigella flexneri uses IpaH1.4 to degrade the LPS ligase RNF213, inhibiting the cell's ubiquitylation abilities. Read more: tinyurl.com/3y4kv2bp #LMBResearch🧪

submitted 9 days ago • 1 comment

How do cells decide on the life or death of a protein? 🔬 Researchers around @haselbachlab.bsky.social at the IMP have captured the first high-resolution view of the human proteasome reading different ubiquitin signals. ➡️Read the full story: imp.ac.at/news/article...

submitted 9 days ago • 1 comment

Biggest commitment to a 3 second joke I've ever seen

submitted 9 days ago • 871 comments

Now this is a sport I could get behind!

submitted 10 days ago • 221 comments

Why are the enhanced PDFs from journals the absolute worst kind of PDF?

submitted 10 days ago • 1 comment

He obviously never should have been confirmed in the first place but for the Health secretary to promote treating measles with steroids and antibiotics should clearly be grounds for his impeachment and removal.

submitted 11 days ago • 9 comments