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bugajlab.bsky.social
Asst. Professor @ Penn Bioengineering. Cell Signaling, optogenetics, synthetic biology, cancer signaling, regenerative medicine, bio-tinkering. www.bugajlab.com
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Posts 11 Comments 23

This Valentine's day I want to share the LOV2 with you! ❤️ Roses are red, the light is blue, stimuli are read by the domain LOV2.

submitted 12 days ago • 1 comment

thanks for the highlight @stemcellpodcast.com!

submitted 13 days ago • 1 comment

We are still looking for postdocs to carry forward this work! Please get in touch if interested in developing thermal protein switches and/or applying them in vivo to study inflammation/cancer.

submitted 30 days ago • 1 comment

Some hope: NOA appeared this morning for a pending new R01 on eRA. Some gears still turning at NIH.

submitted 30 days ago • 0 comments

Excited and grateful that our initial report on temperature-sensitive protein switches is now published @naturemethods.bsky.social Co-led by PhD students Will Benman and @dennishuang.bsky.social www.nature.com/articles/s41... Brief thread:

submitted 33 days ago • 2 comments

Thank you for the highlight Rita! We also think these types of tools will open many new avenues, both fundamental and applied. And kudos for the very thoughtful and fair process @naturemethods.bsky.social

submitted 33 days ago • 2 comments

Wow, what a fantastic Christmas present to get - the main output of my @wellcometrust.bsky.social Henry Wellcome Fellowship is now out @molsystbiol.bsky.social and should be of interest to anybody who loves (PI3K) signalling and quantitative biology! www.embopress.org/doi/full/10....

submitted 68 days ago • 1 comment

We are looking for postdocs! Projects on 1) probes for remote control of cell death and inflammation, and 2) application in vivo to study inflammation in cancer and therapy. Exciting science in an unparalleled environment @ Penn Bioengineering DM or email if interested!

submitted 76 days ago • 0 comments

New direction for our lab: we've worked with light-control of proteins, but the proteins below respond to temperature 🔥❄️. www.biorxiv.org/content/10.1... Introducing Melt, a protein whose localization and clustering can be toggled w/ a few deg C. Led by PhD students Will Benman + Dennis Huang

submitted 371 days ago • 0 comments

interesting and study on how PI3K-activating oncogenes can alter a cell's perception of growth factor ligands. Oncogenes can act as more than just "on-switches" www.biorxiv.org/content/10.1...

submitted 426 days ago • 0 comments

very happy to publish our work on the optoPlateReader, a device for optogenetic stimulation, spectroscopy, and feedback in 96 independently-controlled wells. No special skills to build your own! Started with iGEM, led and finished by coauthors Benman and Datta🥇 www.nature.com/articles/s42...

submitted 457 days ago • 0 comments