chenxinli2.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Hey, Miles' @milesroberts.bsky.social beautiful paper showing that sequence diversity missed by standard methods contributes to Lewontin's paradox is officially published in @evolletters.bsky.social. academic.oup.com/evlett/advan...

submitted 7 hours ago • 3 comments

It’s never about illegal immigration. That’s just an excuse. First international students, then cooks, then agricultural and construction workers. It is plain racism.

submitted 2 hours ago • 0 comments

I am super excited to announce the first (brief) pre-print purely from my group: Start right to end right: authentic open reading frame selection matters www.biorxiv.org/content/10.1... This marks a return to NMD research for me. NMD detects early stop codons but we need to find the true stop!

submitted 1 day ago • 1 comment

UC Davis Botanical Conservatory. I used to intern here in 2013.

submitted 5 hours ago • 1 comment

A little more on RFK's new vaccine committee: Malone - claimed vaccines cause AIDS Kulldorff - promoted mass COVID infection Meissner - opposed vaccines and masks for kids Pebsworth - worked at antivax nonprofit Levi - FL Surgeon General cited his paper when recommending not to get COVID vax

submitted 1 day ago • 136 comments

The amazing Sofia Lövestam initiated the below project, when she became interested in the vault particles that we sometimes observe in #cryoEM images of brain-derived #amyloid filaments. www.biorxiv.org/content/10.1...

submitted 15 days ago • 2 comments

We are not raising prices! While others adjust pricing due to tariff surcharges, we have your back. Any quotes issued this summer will be honored for at least 180 days. We will also do our best to honor any quote that is part of a grant written this summer, regardless of when those funds come in.

submitted 11 hours ago • 0 comments

Pretty interesting one: crossover potential (predicted to be the available precursor for crossover) in Arabidopsis is most highly correlated with H3K4me2/3 (Panel d). From: www.nature.com/articles/s41...

submitted 11 hours ago • 0 comments

Tweet by @biomath.bsky.social who hasn't posted here in 2 months on the decision to leave prices of Illumina sequencing the same despite tariffs, absorbing the difference.

submitted 12 hours ago • 1 comment

Paper alert! #Meiosis4Ever Maximizing meiotic crossover rates reveals the map of Crossover Potential Juli Jing, Qiachao Lian and Stephanie Durand www.nature.com/articles/s41... We pushed meiotic crossover as much has we could, and had some surprises A thread 👇

submitted 12 hours ago • 1 comment

Thanks to Jakob Franke for highlighting the Taxol/FoTO1 gene discovery and the mpXsn approach spearheaded by @cmcclune.bsky.social in @nature.com! Check it out here: www.nature.com/articles/d41... #plants #anti-cancer #singlecell #plantbiology

submitted 1 day ago • 2 comments

Back at Davis attending friends’ commencement

submitted 1 day ago • 0 comments

Today in Nature we report a systematic strategy to activate & identify gene sets in plants. We identify 8 new genes from the yew tree's Taxol biosynthetic pathway, enabling us to engineer tobacco with 17- & 20-gene pathways to Taxol precursors baccatin III & deBz-deoxy-Taxol #SingleCell #secmet 🧬🧪🌾

submitted 1 day ago • 2 comments

1/10 New pre-print(s) from the Sternberg Lab in collaboration with Leifu Chang's Lab! We uncover the unprecedented molecular mechanism of CRISPR-Cas12f-like proteins, which drive RNA-guided transcription independently of canonical promoter motifs. Full story here: www.biorxiv.org/content/10.1...

submitted 1 day ago • 3 comments

Based on some quick math, this alone could fund the NSF Plant Genome Research Program for ~4 years; the NSF Postdoctoral Research Fellowship in Biology, which was totally axed in the NSF budget request, for ~9 years; and ~ half the total NSF GRFP budget

submitted 2 days ago • 3 comments

And eggs still cost too much.

submitted 2 days ago • 0 comments

A call to stand up and show support for the Bethesda Declaration, the NIH, and for federally funded science in general.

submitted 3 days ago • 4 comments

Midst of the labs Genetics publish-athon from @ccaseys.bsky.social. Infecting a population on host genotypes spread across 8 dicots we could show that a generalist pathogen has both generalist and specialist genes url:https://academic.oup.com/genetics/article/doi/10.1093/genetics/iyaf079/8158657

submitted 3 days ago • 2 comments

if white Americans didn’t want Mexicans in California maybe they should not have conquered California from Mexico and then spent 150 years building up an economy entirely dependent on the flow of people and goods across the border just a thought

submitted 3 days ago • 106 comments

Ran into a young Eastern Milksnake eating a DeKay's Brownsnake. Milksnakes are notorious snake eaters but it's rare to see one in action. 🌿🐍📷

submitted 3 days ago • 6 comments

Excited to share my first PhD paper in the @sbmontgom.bsky.social lab with @tamigj.bsky.social (www.biorxiv.org/content/10.1...)! Standard QTL methods treat each gene independently. But what if a single variant regulates multiple nearby genes at once - what we call “allelic proxitropy”? 🧵 ⬇️

submitted 4 days ago • 5 comments

Two exciting papers from Shirasu Lab utilizing the juice of my favorite biological players—Agrobacterium and nematodes—to investigate receptor profiles! 🦠 www.biorxiv.org/content/10.1... 🪱 www.biorxiv.org/content/10.1... Congrats to the authors! 🥳🤩

submitted 86 days ago • 1 comment

Time for another paper from our lab! This time it’s about passage cells. This work originated from a collaboration with @lauraragni.bsky.social and was spearheaded by the super-talented @leoniekraska.bsky.social Below you will find a thread that explains our findings. www.cell.com/cell-reports...

submitted 3 days ago • 5 comments

Considering the Federal situation, campuses are encouraging labs to enter partnerships with industry. A plant breeding company reached out to see if my lab could rate their plant lines for their resistance to Ralstonia. I said "maybe, but these assays require personnel time and materials"

submitted 4 days ago • 1 comment

Reminder: Nobel-prize winning PCR (1983), used in basically all genetic tech today, was only possible because of extremophile bacterium discovered in 1964 in Yellowstone funded by a small ~$80k NSF grant with no obvious application at the time. #science 🧪 www.richmondscientific.com/how-a-discov...

submitted 4 days ago • 22 comments

Almost all Nobel Prizes are awarded for work that is exploratory, or absolutely basic science with no obvious commercial or medical benefit. You cannot predict where advancements come from, so you have to invest in science and scientists. Targeted (corporate) science investment will never do this.

submitted 4 days ago • 4 comments

❗ We have an open post-doc position in our group! 🌱🥔🧬 Are you interested in novel crop breeding techniques and potatoes? If yes, the CRISPS project (in collaboration with Wageningen University and SLU Sweden) may be something for you! You can apply here: jobs.admin.ch/job-vacancie... #NBTs

submitted 4 days ago • 0 comments

Very excited to share our preprint on a new resource: the Encyclopaedia of Viral Anti-Defence Systems (EVADES)! This is the main result of my PhD at ‪EMBL-EBI (@ebi.embl.org)‬ and the University of Cambridge (@cam.ac.uk‬)! 🔗 www.biorxiv.org/content/10.1... 🧵1/n"

submitted 4 days ago • 1 comment

We really are in uncharted territory every week, no?

submitted 4 days ago • 1 comment

As I’m preparing to move again after 4 years, I randomly remembered something. 4 years ago, when I was giving my exist/dissertation seminar, my PhD advisor described me as “courageous, persistent, and creative”.

submitted 5 days ago • 2 comments

🌱 Organic? Plant-based? Looks clean? Safe? 🤔 Not so fast. No matter what you eat, good hygiene and safe practices always matter. Safe food starts with informed choices — every step of the way. Food safety is everyone’s business.

submitted 5 days ago • 4 comments

Control of seed-to-seedling transition by an upstream open reading frame in ABSCISIC ACID DEFICIENT2 www.pnas.org/doi/full/10.... #plantscience

submitted 5 days ago • 0 comments

Genome-Wide Discovery and Characterization of Terpene Synthases Contributing to Strawberry Aroma Metabolism https://www.biorxiv.org/content/10.1101/2025.06.03.654341v1

submitted 6 days ago • 0 comments

In amongst all the excitement I fear many have missed this outstanding bit of trolling by Friedrich Merz. The Chancellor gifted Trump a gilded framed copy of his grandfather’s German birth certificate... reminding Americans that Trump is both the child and grandchild of migrants.

submitted 6 days ago • 248 comments

Redesigning petal shape, size, and color in soybean reveals unexpected phenotypes for floral organ development https://www.biorxiv.org/content/10.1101/2025.06.05.657847v1

submitted 6 days ago • 0 comments

If Chinese netizens are following American politics as entertainment, maybe American voters should really think about what they are doing here.

submitted 6 days ago • 1 comment

Turned 32 today. Celebrate with sake.

submitted 6 days ago • 7 comments

I wrote a quick application note on Tomtom-lite, a Python implementation of the Tomtom algorithm for comparing PWMs against each other. This implementation can be 10-1000x faster and, as a Python function, can be integrated into your workflows easier. www.biorxiv.org/content/10.1...

submitted 9 days ago • 2 comments

How hard is it to get rid of unwanted cloning marbled #crayfish? Marbled crayfish were released into 1️⃣ pond in Prague. The pond got drained. Collected every visible crayfish. Nope: still crayfish. The pond got drained AGAIN. Collected every visible crayfish AGAIN. Nope: still crayfish. 1/4

submitted 6 days ago • 1 comment

🌱 From The Plant Journal: Lettuce variegation is driven by methylation shifts in a retrotransposon and stabilized by an (AT)₅ repeat in a MYB gene promoter. (Dean Lavelle, Richard W. Michelmore) ▶️ onlinelibrary.wiley.com/doi/full/10.... #epigenetics #plantgenetics #plantscience

submitted 6 days ago • 2 comments

In-insect synthesis of oxygen-doped molecular nanocarbons | Science www.science.org/doi/10.1126/... This research is super interesting! An insect is like a function. Insect(an organic compound) = a new organic compound

submitted 6 days ago • 0 comments

Pan-genome and Haplotype Map of Cassava Cultivars and Wild Ancestors Provide Insights into its Adaptive Evolution and Domestication. #CassavaCultivarGenome #ChromosomeLevelAssembly #Pangenome #HaplotypeMaps #Genomics #Bioinformatics @mplantpcom.bsky.social‬ 🧬 🖥️ www.cell.com/molecular-pl...

submitted 6 days ago • 0 comments