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chenxinli2.bsky.social
Also known as “Li” | Assistant Research Scientist @ UGA | Decoding how (epi)genome and development shape (plant specialized) metabolism. | Also post data visualization
2,668 posts 4,022 followers 2,034 following
Prolific Poster

Got to present my art project on flower genetic design to a room full of chaotic and charismatic scientists at Woodstock Bio2 in Prague 🤘 Life is cool. #TCTeAC #theconferencetoendallconferences

We checked the agricultural workers being harassed by “law enforcement” arc, are we heading for the ghorman arc now?

I can’t get over this looming fear for my career. I was optimistic pre-2025. Now I can’t stop thinking about how many scientists of my generation will have to give up on science within a few years.

Humanized Caffeine-Inducible Systems for Controlling Cellular Functions https://www.biorxiv.org/content/10.1101/2025.06.13.659463v1

First they harass international students, then they go after cooks, then agricultural and construction workers. All productive members of our society. #AbolishICE

New additions in fellowships, industry, and academic jobs! If you've recently gotten a fellowship or a job (research, industry, PUI) please consider contributing your application materials. It's a helpful resource for those on the job market! github.com/RILAB/statem...

"TENURE-TRACK FACULTY POSITIONS INSTITUTE OF PLANT AND MICROBIAL BIOLOGY at Academia Sinica, Taipei, Taiwan *Application Deadline: 8/31/2025" Read more here: https://arabidopsis.org/news/jobs/view?file=Tu_6-13-25.pdf #PlantSciJobs

Put this on a billboard.

Glad that you enjoyed it Sjon ! thanks for the post

I’m very happy that my main PhD work, under the supervision of @malick-mbengue.bsky.social, found a home in @pnas.org Two days before my PhD defence! 🎉 (1/6)

We got what I believe to be close to a "perfect" NSF score after our first submission--three "Excellent" reviews, highly competitive. The only minor weakness was that we could reduce our budget. It won't be funded. There is no path forward. I'm devastated.

Hey, Miles' @milesroberts.bsky.social beautiful paper showing that sequence diversity missed by standard methods contributes to Lewontin's paradox is officially published in @evolletters.bsky.social. academic.oup.com/evlett/advan...

It’s never about illegal immigration. That’s just an excuse. First international students, then cooks, then agricultural and construction workers. It is plain racism.

I am super excited to announce the first (brief) pre-print purely from my group: Start right to end right: authentic open reading frame selection matters www.biorxiv.org/content/10.1... This marks a return to NMD research for me. NMD detects early stop codons but we need to find the true stop!

UC Davis Botanical Conservatory. I used to intern here in 2013.

A little more on RFK's new vaccine committee: Malone - claimed vaccines cause AIDS Kulldorff - promoted mass COVID infection Meissner - opposed vaccines and masks for kids Pebsworth - worked at antivax nonprofit Levi - FL Surgeon General cited his paper when recommending not to get COVID vax

The amazing Sofia Lövestam initiated the below project, when she became interested in the vault particles that we sometimes observe in #cryoEM images of brain-derived #amyloid filaments. www.biorxiv.org/content/10.1...

We are not raising prices! While others adjust pricing due to tariff surcharges, we have your back. Any quotes issued this summer will be honored for at least 180 days. We will also do our best to honor any quote that is part of a grant written this summer, regardless of when those funds come in.

Pretty interesting one: crossover potential (predicted to be the available precursor for crossover) in Arabidopsis is most highly correlated with H3K4me2/3 (Panel d). From: www.nature.com/articles/s41...

Tweet by @biomath.bsky.social who hasn't posted here in 2 months on the decision to leave prices of Illumina sequencing the same despite tariffs, absorbing the difference.

Paper alert! #Meiosis4Ever Maximizing meiotic crossover rates reveals the map of Crossover Potential Juli Jing, Qiachao Lian and Stephanie Durand www.nature.com/articles/s41... We pushed meiotic crossover as much has we could, and had some surprises A thread 👇

Thanks to Jakob Franke for highlighting the Taxol/FoTO1 gene discovery and the mpXsn approach spearheaded by @cmcclune.bsky.social in @nature.com! Check it out here: www.nature.com/articles/d41... #plants #anti-cancer #singlecell #plantbiology

Back at Davis attending friends’ commencement

Today in Nature we report a systematic strategy to activate & identify gene sets in plants. We identify 8 new genes from the yew tree's Taxol biosynthetic pathway, enabling us to engineer tobacco with 17- & 20-gene pathways to Taxol precursors baccatin III & deBz-deoxy-Taxol #SingleCell #secmet 🧬🧪🌾

1/10 New pre-print(s) from the Sternberg Lab in collaboration with Leifu Chang's Lab! We uncover the unprecedented molecular mechanism of CRISPR-Cas12f-like proteins, which drive RNA-guided transcription independently of canonical promoter motifs. Full story here: www.biorxiv.org/content/10.1...

Based on some quick math, this alone could fund the NSF Plant Genome Research Program for ~4 years; the NSF Postdoctoral Research Fellowship in Biology, which was totally axed in the NSF budget request, for ~9 years; and ~ half the total NSF GRFP budget

And eggs still cost too much.

A call to stand up and show support for the Bethesda Declaration, the NIH, and for federally funded science in general.

Midst of the labs Genetics publish-athon from @ccaseys.bsky.social. Infecting a population on host genotypes spread across 8 dicots we could show that a generalist pathogen has both generalist and specialist genes url:https://academic.oup.com/genetics/article/doi/10.1093/genetics/iyaf079/8158657

if white Americans didn’t want Mexicans in California maybe they should not have conquered California from Mexico and then spent 150 years building up an economy entirely dependent on the flow of people and goods across the border just a thought

Ran into a young Eastern Milksnake eating a DeKay's Brownsnake. Milksnakes are notorious snake eaters but it's rare to see one in action. 🌿🐍📷

Excited to share my first PhD paper in the @sbmontgom.bsky.social lab with @tamigj.bsky.social (www.biorxiv.org/content/10.1...)! Standard QTL methods treat each gene independently. But what if a single variant regulates multiple nearby genes at once - what we call “allelic proxitropy”? 🧵 ⬇️

Two exciting papers from Shirasu Lab utilizing the *juice* of my favorite biological players—Agrobacterium and nematodes—to investigate receptor profiles! 🦠 www.biorxiv.org/content/10.1... 🪱 www.biorxiv.org/content/10.1... Congrats to the authors! 🥳🤩

Time for another paper from our lab! This time it’s about passage cells. This work originated from a collaboration with @lauraragni.bsky.social and was spearheaded by the super-talented @leoniekraska.bsky.social Below you will find a thread that explains our findings. www.cell.com/cell-reports...

Considering the Federal situation, campuses are encouraging labs to enter partnerships with industry. A plant breeding company reached out to see if my lab could rate their plant lines for their resistance to Ralstonia. I said "maybe, but these assays require personnel time and materials"

Reminder: Nobel-prize winning PCR (1983), used in basically all genetic tech today, was only possible because of extremophile bacterium discovered in 1964 in Yellowstone funded by a small ~$80k NSF grant with no obvious application at the time. #science 🧪 www.richmondscientific.com/how-a-discov...

Almost all Nobel Prizes are awarded for work that is exploratory, or absolutely basic science with no obvious commercial or medical benefit. You cannot predict where advancements come from, so you have to invest in science and scientists. Targeted (corporate) science investment will never do this.

❗ We have an open post-doc position in our group! 🌱🥔🧬 Are you interested in novel crop breeding techniques and potatoes? If yes, the CRISPS project (in collaboration with Wageningen University and SLU Sweden) may be something for you! You can apply here: jobs.admin.ch/job-vacancie... #NBTs

Very excited to share our preprint on a new resource: the Encyclopaedia of Viral Anti-Defence Systems (EVADES)! This is the main result of my PhD at ‪EMBL-EBI (@ebi.embl.org)‬ and the University of Cambridge (@cam.ac.uk‬)! 🔗 www.biorxiv.org/content/10.1... 🧵1/n"

We really are in uncharted territory every week, no?

As I’m preparing to move again after 4 years, I randomly remembered something. 4 years ago, when I was giving my exist/dissertation seminar, my PhD advisor described me as “courageous, persistent, and creative”.

🌱 Organic? Plant-based? Looks clean? Safe? 🤔 Not so fast. No matter what you eat, good hygiene and safe practices always matter. Safe food starts with informed choices — every step of the way. Food safety is everyone’s business.

Control of seed-to-seedling transition by an upstream open reading frame in ABSCISIC ACID DEFICIENT2 www.pnas.org/doi/full/10.... #plantscience

Genome-Wide Discovery and Characterization of Terpene Synthases Contributing to Strawberry Aroma Metabolism https://www.biorxiv.org/content/10.1101/2025.06.03.654341v1

In amongst all the excitement I fear many have missed this outstanding bit of trolling by Friedrich Merz. The Chancellor gifted Trump a gilded framed copy of his grandfather’s German birth certificate... reminding Americans that Trump is both the child and grandchild of migrants.