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cp-cell.bsky.social
Cell aims to publish the most exciting and provocative research in biology. Posts by Scientific Editors on the Cell editorial team. See the latest papers at https://www.cell.com/cell/
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Prolific Poster

Now online! Microbiome mismatches from microbiota transplants lead to persistent off-target metabolic and immunomodulatory effects

Explore the International Trained Immunity collection! This collection of papers across Cell Press journals is focused on understanding the mechanisms of trained immunity in innate immune cells. hubs.li/Q03j0ppn0

Excited to share our latest update on @cp-cell.bsky.social! We introduce VICAR (VIral-induced Centromeric DNA Amplification and Recognition) : a newly identified nuclear cGAS defense system to detect viruses. www.cell.com/cell/abstrac...

#LocationLocationLocation! #NewVirusSensingModality! Lahaye, @manellab.bsky.social &co show @cp-cell.bsky.social that nuclear cGAS senses viruses by recognizing centromeric DNA amplification caused by viral effectors that degrade centromere proteins! www.cell.com/cell/abstrac...

When Machine Learning meets Bioorthogonal Chemistry? Imagine an AI-powered "molecular switch" in living organisms, activated on demand! A #PKUResearch team, led by Profs. Chen Peng & Wang Chu, developed CAGE-Proxᵛⁱᵛᵒ—enabling precise protein activation in living mice. www.cell.com/cell/abstrac...

Thrilled to share our latest @cp-cell.bsky.social. We present VICAR (VIral-induced Centromeric DNA Amplification and Recognition), a new defense system to detect viruses in the nucleus based on nuclear cGAS. www.cell.com/cell/abstrac...

Now online! Centromeric DNA amplification triggered by viral proteins activates nuclear cGAS

Now online! Infrequent strong connections constrain connectomic predictions of neuronal function

The new issue is out! 👉 cell.com/cell/current On the cover, Ziogas et al. demonstrate that lactate produced by monocytes can confer long-term epigenetic memory and regulate secondary responses through histone lactylation. 📷credit: A. Ziogas, Hefei Sondii Media Technology

Now online! A microbial amino-acid-conjugated bile acid, tryptophan-cholic acid, improves glucose homeostasis via the orphan receptor MRGPRE

Now online! Machine-learning-assisted universal protein activation in living mice

Now online! Personalized molecular signatures of insulin resistance and type 2 diabetes

Now online! De novo assembly of nuclear stress bodies rearranges and enhances NFIL3 to restrain acute inflammatory responses

Now online! Cross-organ metabolite production and consumption in healthy and atherogenic conditions

Now online! The contribution of pelagic fungi to ocean biomass

Now online! Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates

Excited our paper is out in Cell @cp-cell.bsky.social! 🧬⚡ DNA photo-crosslinking proteomics in living cells 🎯 Pinpoints protein-DNA interactions to single amino acids 🌎 Globally quantifies DNA binding for >1800 proteins at a timescale of minutes 🔗 www.cell.com/cell/fulltex... 🧵

This collection describes a range of methods allowing access to neuronal and non-neuronal cell types, opening the door to targeting the nervous system in ways that were previously unimaginable 🧠 Check out our BRAIN Armamentarium Consortium🧵 www.cell.com/consortium/b...

Now online! The human proteome with direct physical access to DNA

Now online! Inheritance of acquired adaptive cold tolerance in rice through DNA methylation

Now online! Near-infrared spatiotemporal color vision in humans enabled by upconversion contact lenses

Can serotonin and SSRIs help T cells kill cancer? Our @cp-cell.bsky.social article by Dr. Bo Li, doctoral candidate James Elsten-Brown and their team reports "Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis!" www.cell.com/cell/fulltex...

Thrilled to share that my main postdoctoral project in Josh Rabinowitz’s lab is out today at @cp-cell.bsky.social ! We found an unexpected, diet- and microbiota-dependent mechanism that affects the anticancer activity of PI3K inhibitors. Thread below 👇

Now online! A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types

#NeuroImmunologyPower! Yang, Li, &co show @cp-cell.bsky.social that the serotonin transporter depletes intratumoral level of serotonin dampening CD8 T cell antitumor immunity. Using an antidepressive that blocks the transporter reduces tumor growth & potentiates PD1 blockade therapy! t.co/NRhBZiFLIc

Now online! Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis

Predator-prey interplay: When chemical conversation turns deadly Highlight of a recent @cp-cell.bsky.social‬ paper discovering a chemical radar used by the plant pathogen Pseudomonas syringae to sense and kill an amoeba predator. www.cell.com/cell-host-mi...

Now online! Integrating reproductive states and social cues in the control of sociosexual behaviors

Now online! Microbiome metabolism of dietary phytochemicals controls the anticancer activity of PI3K inhibitors

Now online! Arrestin-biased allosteric modulator of neurotensin receptor 1 alleviates acute and chronic pain

Abstract deadline extended to May 23rd! Join us in NYC in Sept 2025 for the Cell Symposium "The Neuro-immune Axis: Charting the periphery" #CSNeuroimmune25 #neuroimmunology Organized by @cp-neuron.bsky.social, @kavithascranton.bsky.social, Brian Kim & David Artis hubs.ly/Q03gmh5w0

New paper from @santoslab.bsky.social lab. Huge congrats to @borzogharibi.bsky.social & @oliveringe.bsky.social for this amazing work!

Was so lovely to be part of this work with @borzogharibi.bsky.social @santoslab.bsky.social ! Read below to learn more about this cool new model of extra-embryonic development.

Online now at @cp-cell.bsky.social , the culmination of a 12-year effort. 🧵 to follow later this evening www.cell.com/cell/fulltex...

#ResearchRewind: "Habitual daily intake of a sweet and fatty snack modulates reward processing in humans" http://dlvr.it/TKpWQq @cp-cellmetabolism.bsky.social @danasmall.bsky.social

Now online! Repeat-element RNAs integrate a neuronal growth circuit

The new issue is out! 👉 cell.com/cell/current On the cover, Beckwith and Brunner et al. uncover that chromosomes self-organize into their characteristic mitotic rod shape through the formation of large and extensively overlapping DNA loops 📷credit: Andreas Brunner.

May issue is online! Explore reviews on the #neuroimmune axis! The beautiful cover was designed by Ella Marushchenko, working with @jonykipnis.bsky.social. A brain encased in a walnut shell that is cracking open symbolizes our growing understanding of #neuroimmunology www.cell.com/immunity/iss...

Now online! Structural insights into auxin influx mediated by the Arabidopsis AUX1

Now online! LoxCode in vivo barcoding reveals epiblast clonal fate bias to fetal organs

Now online! Post-gastrulation amnioids as a stem cell-derived model of human extra-embryonic development

Now online! Immunotherapy-related cognitive impairment after CAR T cell therapy in mice

Sooo happy to finally have this one published!! (3 years in the making… 👀) A comprehensive investigation into the recency and geographical origins of both SARS-CoVs that spilled to humans in the past few decades, now in @cp-cell.bsky.social www.cell.com/cell/fulltex...