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delafuentelab.bsky.social
Presidential Associate Professor @upenn.bsky.social - using AI to reimagine antibiotic discovery and peptide design. Previously @MIT, @UBC 🔗 https://delafuentelab.seas.upenn.edu
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Un placer haber estado en el podcast de @jordiwild.bsky.social #TheWildProject. Hablamos de ciencia, inteligencia artificial, antibióticos y del enorme reto que representan las superbacterias... ¡y mucho más! ¡Gracias por la charla! 🎧 Puedes verlo aquí 👉 www.youtube.com/watch?v=BWQ_...

New Article! Tutorial: guidelines for the use of machine learning methods to mine genomes and proteomes for antibiotic discovery

(1/4) Artificial intelligence may be one of the most important tools we have in the global fight against AMR, which now contributes to 4.5 million deaths each year.

Ha sido un placer charlar con Teba Chacon en La Ventana de las Rías de Radio Coruña @cadenaser.com sobre mi infancia en A Coruña y mi pasión por la ciencia. Aquí podéis ver la entrevista completa: www.youtube.com/watch?v=-0ks...

Glad to have joined the Wharton Biotech Conference @upenn.bsky.social last week to discuss how cutting-edge AI can unlock personalised medicine and a new generation of antibiotics. Thanks to Irene Rombel, Morgan Cheatham, and Derek Oldridge for the great conversation!

Grateful to @phillymag.com for spotlighting our team’s work using dvanced AI to accelerate antibiotic discovery—an example of how machine intelligence can help science stay ahead of infectious disease for the benefit of humanity. 🔗 www.phillymag.com/technology-l...

Great to see @delafuentelab.bsky.social in this article! You can see the discussion he gave as part of a T-CAIREM speaker series here: youtu.be/NQU9JtV37u0?... • New #AI technique uncovers antiviral compounds www.pennmedicine.org/news/news-re... #MedSky #AImedicine #HealthAI #Healthcare #MedTech

César de la Fuente: «Las superbacterias son la gran amenaza para la humanidad» https://www.lavozdegalicia.es/noticia/sociedad/2025/04/16/cesar-fuente-superbacterias-gran-amenaza-humanidad/00031744821156356693172.htm

Great paper out this week by @delafuentelab.bsky.social - summarised nicely in this thread! 🧵

(1/5)Delighted to share our new study in @cp-cellrepphyssci.bsky.social @cellpress.bsky.social, a glimpse of how intelligent systems can accelerate biology when data are scarce.

It was wonderful to visit the Bell Labs of biology @hhmijanelia.bsky.social! Huge thanks to Luke Lavis for having me! Stephan Saalfeld @agtebo.bsky.social ‪@sciencethecat.bsky.social‬ and more!

Honored to pen this tribute to my mentor Bob Hancock. He taught me to write science (when my English was shaky at best) and, more importantly, to think like a scientist. Thank you, Bob! Read it here: @pubs.acs.org pubs.acs.org/doi/10.1021/...

Excited to share my keynote lecture from the event "Accelerating Discoveries in Biology and Medicine Using AI", hosted by @uoft.bsky.social, @uoftpandemics.bsky.social! Check it out here: www.youtube.com/watch?v=NQU9...

A CORUÑA 👉 El profesor de la Universidad de Pensilvania ha recibido este reconocimiento por su trabajo pionero en el descubrimiento de antibióticos con IA

El gallego César de la Fuente es nombrado Joven Líder Global 2025 por el Foro Económico Mundial

(1/2) I'm honored to be named a Young Global Leader by @weforum.org. I cannot wait to see how we can continue accelerating scientific discoveries, enabled by AI and ground-truth experiments, to tackle urgent threats like drug resistance before they reach a crisis point. #YGL25 #WEF25

Last week, I had the pleasure of visiting the @duke-university.bsky.social Center for Biomolecular and Tissue Engineering to discuss our latest work using AI to accelerate antibiotic discovery. Thank you @pranam.bsky.social, @chorye.bsky.social, and more!

El uso de la IA y la desextinción molecular en la búsqueda de nuevos antibióticos es un tema que nos apasiona. Gracias por contar con nosotros en este artículo @abc.es

🚨 Are we ready for the next pandemic? I'm hugely optimistic about humanity's ability to overcome crises—but less so about preventing them altogether. @pennlive.com 🔗 www.pennlive.com/news/2025/03...

Join us April 14 for the RSC Americas Emerging Investigators webinar on AI/ML in Chemistry! Featuring talks from Jolene Reid (UBC), César de la Fuente (UPenn) @delafuentelab.bsky.social, Adji Bousso Dieng (Princeton) @adjiboussodieng.bsky.social, and Connor Coley (MIT) rsc.zoom.us/webinar/regi...

My best experiment yet ❤️

Wonderful to join today’s @nam.edu panel in DC to discuss drug discovery, AMR & AI with rockstars Latanian Logan, Cassandra Quave, Anita Shukla & Gail Cassell. Fantastic opening lecture by @deisseroth.bsky.social and inspiring words from Victor Dzau!

El gallego César de la Fuente recibe el premio Fleming: "Es una responsabilidad y un honor" #ACoruña #Coruña #Galicia

Superb end of the day with Fleming Prize Lecture by @delafuentelab.bsky.social @microbiologysociety.org #Microbio25

(1/2) I am deeply honored to receive the Fleming Prize, named after one of my scientific heroes who transformed medicine with the discovery of penicillin. @microbiologysociety.org @upenn.bsky.social

🐸🔬 Exciting news! Our research designing new synthetic antibiotics by leveraging the host defense mechanisms of frogs has been featured on Phys org! @cp-trendsbiotech.bsky.social @cellpress.bsky.social Discover how these findings could lead to new antibiotics

La rana andersonii fue nuestra fuente de inspiración para el descubrimiento de nuevos antibióticos. Fantástico trabajo del equipo, incluyendo a la coruñesa Lucía Ageitos. ¡Gracias @lavozdegalicia-bot.bsky.social! @cp-trendsbiotech.bsky.social @cellpress.bsky.social

Las ranas viven en ambientes muy contaminados, repletos de microorganismos, y aun así no se infectan. Nos inspiramos en sus moléculas defensivas para diseñar antibióticos sintéticos con resultados prometedores a nivel preclínico. Gracias a Raúl Limón y a @elpais.com

Frogs thrive in highly polluted environments full of microorganisms, yet they don’t get infected. Inspired by their defensive molecules, we designing synthetic antibiotics with promising preclinical results. @cp-trendsbiotech.bsky.social @cellpress.bsky.social @upenn.bsky.social!

Great work be the @delafuentelab.bsky.social using Andersonin-D1, an antimicrobial peptide of a frog, as basis to generate potent synthetic peptide antimicrobials by structure-guided design www.cell.com/trends/biote...

La lucha contra las superbacterias es un gran problema global. Gracias @diariodeleon.es por escribir sobre nuestra última publicación en @cp-trendsbiotech.bsky.social @cellpress.bsky.social

Emocionado de que nuestra última investigación sobre antibióticos derivados de la rana 'Odorrana andersonii' haya sido destacada en La Nueva Crónica! Estos hallazgos podrían ser clave contra las superbacterias.

Una carrera frente a la caída de la eficiencia de los antibióticos actuales que amenaza con convertirse en uno de los principales frentes de mortalidad en los próximos años 👇 https://leer.diariodeleon.es/dha8z4

Using frog secretions as inspiration, @delafuentelab.bsky.social created new antibiotic candidates that could help fight drug-resistant infections. Read more: blog.seas.upenn.edu/scientists-u...

🐸 Check out this thread describing a fascinating paper just published in Trends in Biotechnology - discovering antimicrobial peptides in frogs 🐸