dhlwilson.bsky.social
Research Fellow in Translational & Regenerative Medicine.
Interested in understanding and developing cell therapies for Type 1 Diabetes and Liver Disease.
Zymurgist and Wrangler of Bumblenuts
Takes the scenic route 🌳 🏃🚴 | Edinburgh, UK | He/Him 🌈
100 posts
663 followers
401 following
Regular Contributor
Active Commenter
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Well done.
#ThePandTheD
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Which reminds me of these words from @humblethepoet.bsky.social
Get out there. Be uncomfortable. Make mistakes. Get embarrassed. We'll all be dead soon, it's not a big deal.
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Will keep me eyes peeled!
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Playing the same game this week.
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#SciHub still a thing?
#AcademicSky
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Wrestling with the question of which platform to use in combination with snRNA-seq.
Not a problem we had a few years ago!
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Need more media coverage of pissed off Americans.
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First timer here. A great cross section of the community, loads of diverse conversations, learned loads I didn't expect to.
#DUKPC25 #Type1Diabetes #Diabetes @diabetesuk.bsky.social @stevemorganfdn.bsky.social
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Love it Izzy, bring your best self.
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Keen to engage with @stevemorganfdn.bsky.social @breakthrought1duk.bsky.social friends and collaborators contributing to #Type1DiabetesGrandChallenge research.
#DiabetesUK #DiabetesUKConference #DUK2025 #DUKPC2025 #Type1Diabetes #Diabetes #Omics #Multiomics #SingleCell #Spatial #Transcriptomics🧪🧬🔬
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Great stuff Aaron, well done. I'll put some time aside to have a look at this.
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It'll be a tragic case study.
Not to mention that international travel will impact the lives and health services worldwide.
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AI is the much vaunted solution to just about everything.
I'm sure it will be helpful in the future but at the moment feels like a glorified spell checker...
#ThisSkeetLacksNuance #AI
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👋 #LiverSky
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Tbh, pan-endocrine (alpha, beta, etc) would do it but getting a bit bogged down with Grompe and subpopulation specificity.
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True, who doesn't love a UMAP!
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"They"'re never that self-aware. 😂
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Tbh, pan-endocrine (alpha, beta, etc) would do it but getting a bit bogged down with Grompe and subpopulation specificity.
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Tough evening in the office for the Welsh. The rest of us might be in trouble this year.
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Nice try Tommy 😉😂
#SingleCell
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Describing him as not a "details" person is being polite.
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Further background:
Hypoimmune islets achieve insulin independence after allogeneic transplantation in a fully immunocompetent non-human primate
www.cell.com/cell-stem-ce...
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Exciting because:
1️⃣No Immunosuppression: limiting associated health risks and treatment challenges.
2️⃣Immune response is a key factor in poor engraftment, abrogating this will improve long-term functionality.
3️⃣Scalable and Accessible: applicable to engineered cells, making it widely available.
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The cells and patient:
1️⃣ Produced insulin naturally).
2️⃣ Responded to meals, increasing insulin production appropriately.
3️⃣ Evaded immune system attack without requiring immunosuppressive drugs.
4️⃣ Showed graft survival via MRI scans at 28 days post-transplantation.
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These were donor derived pancreatic islet cells engineered with Sana’s Hypoimmune (HIP) technology into a patient with type 1 diabetes.