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diarmuidkenny.bsky.social
Proteomics group leader..... Scale modelling when I can
37 posts 587 followers 388 following
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Hey #TeamMassSpec, with all the super duper ultra fast TOF based DIA methods out there, how are you managing the throughput & depth on your old tribrids, QEs and Exploris? Any TMT aficionados out here getting 30spd, for instance, or even 15 with >8k proteins?

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The lack of symmetry is really annoying. The port wing root broke which has resulted in the offset. 😭

Where do people put their #scalemodels when complete? Mine ends up in the attic, unseen as I have no space to display

I follow back people, though I'm struggling to keep up when requests. I'll get there eventually

Hey #TeamMassSpecv of you only have one mass spec and you are running TMT, what is your preferred number of fractions (is you balancing depth of coverage with instrument time). Currently we are at 16 though curious as to what others do

Anyone doing #proteomics have any experience of using Attobodies (alamarbio.com/technology/a...). Looks like an interesting platform (in the same vein as olink or somalogic

Hi #TeamMassSpec. What are you thoughts on running DIA with FAIMS and only using one compensation voltage? (So instead of running with for example 40 + 60, we only ran with 50)

Dear new glyco friends, here’s a starter pack we can work on, so we can bootstrap some great community on here. go.bsky.app/QTL6EqT

First of two funded PhD positions in the lab - study norovirus replication with mass spectrometry, and molecular virology!

🧬 We're looking for an intern for summer 2025 to work with me and the data science and engineering team at Talus Bio! Apply here 👇 talusbio.applicantpro.com/jobs/3551253

They're not on Bluesky but Ubuntu #Proteomics Summer School has started! I'll try to live skeet as much as I can.

A good line manager makes all the difference..... Unfortunately so does a bad one!

Is coffee stout a legitimate morning ale?

Looking at my most recent dataset.....DDA is dead. Long live DIA.

Started weathering on the spitfire.

FAIMS Vs No FAIMS.. Higher number of peptide IDs and lower TIC: FAIMS Lower number of peptide IDs and higher TIC: No FAIMS 100ng HeLa QC monitored on QCloud2..

I get a shiny new thermo Vanquish on Monday. No more late nights trying to get my, by now ancient, (Dioniex) Ultimate 3000 to actually work. Woot!

Trying some affinity selection mass spec (the lesser known ) ASMS. Had a lovely positive control ... Bit of QC later and it turns out we have non specific binding. Down a rabbit hole if potential solutions now

#TeamMassSpec.. Do you have a Thermo Ascend?? If yes, can I know what is it's FHCD collision pressure readback?? Is it 1.7 mTorr or 8 mTorr?? Thanks very much..

The spitfire is ready for decals