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dweisman.bsky.social
Neurologist, trialist, focused on Alzheimer’s disease. Skeptical doesn’t mean cynical.
296 posts 509 followers 554 following
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Posts 16 Comments 34

AD testing outside physician's direct care has zero pre-test probability, no clinical input or context. This will kill people. Neurogen might become another word for Theranos. firstwordhealthtech.com/story/5936237

submitted 3 days ago • 0 comments

People without a disease are healthy. www.nytimes.com/2024/04/29/w...

submitted 5 days ago • 0 comments

Piller is not operating in good faith. Takes on conspiracy theorist mindset, selecting and elevating the ideas that confirm his truth. Don’t think Piller is reliable, still sad to read LS minimizing AD in the 80s. Yes, die with it, but gets ugly. www.statnews.com/2025/02/14/a... via @statnews.com

submitted 6 days ago • 2 comments

Next vacation spot!!!

submitted 6 days ago • 0 comments

"So, scientists voted with their test-tubes: They work on amyloid because the evidence for a causative role is strong. There is no restrictive 'mafia'" - www.statnews.com/2025/02/14/a...

submitted 6 days ago • 1 comment

Doctors waiting to euthanize their patients with Alzheimer’s disease, but no mention of helping delay disease progression into the stage their patients fear over death. www.nytimes.com/2025/02/16/h...

submitted 6 days ago • 0 comments

I’m about to come back to the US. How’s it going back there?

submitted 9 days ago • 2 comments

I don’t usually leave the office, but got out to Seoul for a few days. Cold but wonderful. Amazing food, people, culture.

submitted 14 days ago • 0 comments

@davidrind.bsky.social - Did the ‘Psymposia’ folks lie to you? Article seems clear they lied about some of the alleged misconduct. The entire thing seems like a whole lot of mess, no lessons learned, and the possible delay of definitive data. www.nytimes.com/2025/02/04/h...

submitted 18 days ago • 0 comments

@nytimes.com another bad Alzheimer piece. Citing a study with negative primary endpoints as encouraging, mistaking prevention for treatment, puffing up an uncertain mechanism. How about lean into our ignorance until semaglutide reads out? www.nytimes.com/2025/01/31/w...

submitted 21 days ago • 2 comments

Required reading that routs the op/ed in the NY Times about the trumped up "Devastating Legacy of Lies in Alzheimer's."

submitted 23 days ago • 0 comments

Wow, this has been a pipe dream for decades: a non-opioid pain reliever that takes advantage of sodium channels. Congratulations to all involved with Journavx, the birth of a new drug class, and thank you to all sites, subjects, and risk takers. www.fda.gov/news-events/...

submitted 23 days ago • 0 comments

Tattoo convention with kiddo. We didn’t get any.

submitted 26 days ago • 0 comments

Good news. FDA just approved lecanemab monthly dosing for maintenance after 18 months on therapy. This will reduce burden. www.prnewswire.com/news-release...

submitted 27 days ago • 0 comments

Great thread. A lot of chronic cognitve problems end up in the ER after acute events.

submitted 29 days ago • 0 comments

This is a great talk, many good lessons and ways to cultivate your thinking. youtu.be/D3z5kIANta0

submitted 35 days ago • 0 comments