gallardo-seq.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

“You aren’t kissing Dear Leader’s ass enough” is a helluva foreign policy.

submitted 21 hours ago • 1 comment

Read every word of this article to see what the Trump folks are doing to the good civil servants at NIH -- and to the important work that protects all of our health. www.theatlantic.com/health/archi...

submitted 1 day ago • 8 comments

Five alarm fire. www.politico.com/news/2025/02...

submitted 2 days ago • 759 comments

RNA xkcd.com/3056

submitted 3 days ago • 161 comments

Biomedical graduate admissions paused or cut back as some universities respond to Trump orders on research - STAT apple.news/APlQhGHRrSfy...

submitted 9 days ago • 0 comments

You excited for March 7th?! Get in contact with local organizers at your state capitols! airtable.com/app4h5wUssMG...

submitted 12 days ago • 1 comment

Sickening how the mainstream media and our elected representatives have been so passive about this constitutional crisis.

submitted 25 days ago • 0 comments

and unconstitutional…

submitted 26 days ago • 0 comments

Dems must go on the offensive. Our country’s safety is at risk

submitted 29 days ago • 2 comments

Ah. Clearly DEI mandates led to the hiring of invisible people.

submitted 29 days ago • 8 comments

how it feels to be working on RPPRs right now.

submitted 37 days ago • 0 comments

Study Sections (and Advisory Councils) scheduled between now and Feb 2nd Extremely alarming nonetheless, but let's make sure people have accurate info.

submitted 37 days ago • 2 comments

H/t to Nava for spotting this & posting to ASeq discord First question posted to @nanopore CEO Gordon Sanghera at #JPM25 had 2 parts: 1. Do they have long read technology? 2. Do they see value in long reads?

submitted 45 days ago • 4 comments

🤯

submitted 70 days ago • 0 comments

Hi Bluesky, just in time for the holidays I am excited to share the latest pre-print from my group! We solved the 3D structure of a mysterious viral RNA that resists degradation by host nucleases. A short 🧵 &link below – please also check out the full video! #RNA #RNAbiology #RNASky #lovevirology

submitted 71 days ago • 8 comments

My replies are perpetually full of anti-vaxxers these days telling me about polio vaccines. Not shockingly, most of what they are saying is wrong. Luckily, I trained with Vincent Racaniello & he taught me a few things about poliovirus. So let’s discuss the king of the Picornaviridae👇🏻

submitted 73 days ago • 36 comments

Just had my first experience with CycloneSEQ data and shared my findings in this blog post: rrwick.github.io/2024/12/17/c... How does CycloneSEQ compare to @nanoporetech.com? I looked at both read-level and consensus-level accuracy. Check it out!

submitted 74 days ago • 0 comments

Research thrives on innovation and the diversity of ideas, yet our funding system often penalizes both. In our new study published in PNAS, we explore the hidden costs of competition in allocating scarce research funds. (1/10) www.pnas.org/doi/10.1073/...

submitted 88 days ago • 4 comments

Reply below if you want to be included in the #nanopore starter pack! go.bsky.app/VCoo6T

submitted 91 days ago • 14 comments

TechBio Transformers (founded by @dr-alphalyrae.bsky.social) is a growing global community of folks who want to (+)ly impact the field of technology & biology, while also intentionally building healthy dialogue and community Follow along, & even consider joining the group! bsky.app/starter-pack...

submitted 95 days ago • 2 comments

It’s great to see this thorough validation of DMS chemical probing of RNA structure. I think the DMS reactivity “continuum” issue and the interplay with sequence context issue can be addressed with new ML models combined with 4-base sensitive DMS.

submitted 95 days ago • 1 comment

RNAkinet identifies nascent RNA by predicting 5EU metabolically labeled #RNA from raw #nanopore electrical signal. Should allow association of RNA metabolism dynamics with isoform usage, poly(A) tails and native RNA mods. academic.oup.com/nargab/artic...

submitted 97 days ago • 3 comments

I wrote about the National Institutes of Health and the various serious and unserious proposals for NIH reform that have been floating around. It is important to understand how this agency actually functions and point criticism at the right problems. A short 🧵:

submitted 97 days ago • 7 comments

Welcome!!

submitted 98 days ago • 0 comments

Hi #RNAsky, I've made a much needed #RNA modifications starter pack! Let me know if you’d like to be added or know someone who should be. go.bsky.app/E7zXGSF #RNAmodifications

submitted 99 days ago • 22 comments

🚨 Update for #RNA science fans: I checked on #Bsky registry, and here is a 'condensate' (😆) of all #RNA #RNAsky starter packs so far: 1. General RNA biology #1 go.bsky.app/RN6HnZp

submitted 100 days ago • 30 comments

How to call SNV in RNA seq from Nanopore / Pacbio ? Easy: Clair-3RNA biorxiv.org/content/10.1... ~95% / ~96% F1-score for ONT / PacBio + we detect RNA editing! Great collaboration with Ruibang Luo, his group + Miten Jain ( need to invite them over here). Special thanks to Justin Zook from GIAB!

submitted 102 days ago • 1 comment

Here for my first post. Our new approach to study tRNA aminoacylation by nanopore sequencing. Started as a napkin sketch ~1 year ago! This was a fun one, congrats to @laurakwhite.bsky.social and Aleks. www.biorxiv.org/content/10.1...

submitted 102 days ago • 2 comments

Although the wind was screaming in my ears, it was a scene of serenity & breathtaking majesty as the Cuernos del Paine lit up in magnificent light. Light I had never witnessed in 5 years of exploring Patagonia. 📷 #photography #nature #naturephotography #landscape #landscapephotography #mountains

submitted 102 days ago • 37 comments

New paper from Amit Khandhar’s team at HDT Bio demonstrating that our LION/repRNA platform can be thermostabilized by lyophilization, enabling refrigerator stability for at least 1 year! Clear implications for global access to vaccines based on our technology. authors.elsevier.com/c/1k6n4cI2-5...

submitted 103 days ago • 0 comments

I made a genomics technologies starter pack. It's a work in progress. Please let me know if you want to be added or if missed anyone. go.bsky.app/3oiGMBe

submitted 107 days ago • 25 comments

RFK Jr. says he wants the National Institutes of Health to “pivot” from studying infectious disease and focus on chronic diseases, which he claims have been “neglected”. There are currently 20+ Institutes at the NIH. Of these, there is a total of one focused on Infectious Disease…

submitted 106 days ago • 34 comments

devider: long-read reconstruction of many diverse haplotypes https://www.biorxiv.org/content/10.1101/2024.11.05.621838v1

submitted 112 days ago • 0 comments

My half-hearted attempt to start a structural virology starter pack. Could be useful for conference organisation in the future! 😀 go.bsky.app/Qxv95BL Comment below if you'd like me to add you, or anyone you recommend! #virology #cryoEM

submitted 107 days ago • 22 comments

The final version of our study using pseudovirus deep mutational scanning to measure the effects of mutations influenza H5 hemagglutinin to inform viral surveillance is now published in PLoS Biology: journals.plos.org/plosbiology/...

submitted 108 days ago • 2 comments

Our new preprint from Briggs lab is out! We solved the in-virus #cryoEM structure of the HIV matrix protein by SPA. The structure led us to a discovery resolving a long mystery in HIV biology – a peptide SP2 triggers the maturation of the HIV matrix domain. A 🧵 1/x Paper: tinyurl.com/c7szhtfa

submitted 108 days ago • 1 comment

I created a genomics+bioinformatics starter pack. If I left you off, please reply and I'll add you! go.bsky.app/B5YYBfq

submitted 130 days ago • 99 comments