gbdownes.bsky.social
Dad of two, Professor of Biology @UMass, rare disease researcher and advocate, SPINES @MBL director, and runner. I use zebrafish to study the genetic control of locomotion and epilepsy genes. 🧪🧬ðŸ§
245 posts
2,230 followers
860 following
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📌
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Elite universities have totally lost their way. No leadership, no courage, and few protections around scholarship.
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They have already fired people at the NOAA aquarium.
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Very true. This is why we don't use Methylene Blue, especially when performing behavioral analysis.
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Big congratulations to Madison Riffe, a spectacular graduate student in my lab! She wrote this review as part of @biologyopen.bsky.social Future Leader Review. Her idea! Madison is looking for a postdoc so reach out if you're interested. Whatever lab she selects will be VERY lucky to land her. (4/4)
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If these disorders do constitute a new disease class, it could present an opportunity for understanding them, developing new therapies, and combining patient advocacy efforts. (3/4)
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We review the clinical findings of these diseases and the efforts to model them in cells and animal systems, including #zebrafish. (2/4)
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🦗🦗🦗
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📌
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Universities are the target, doesn’t matter if they’re wearing a target or not.
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*some things
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If you like my comments, don’t forget to like and subscribe.
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We don’t wear lab coats very much either, but I’m not about to let this sponsorship opportunity go to waste!
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I personally envision our lab coats emblazoned with logos, like a race car driver.
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Now we get to see which institutions really walk the talk versus those that support diversity only when it’s fashionable. Taking notes.
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This seems like a you problem.
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I think it’s a misconception to say the NIH/NSF faucet has been turned back on. The freeze is still in place. Outside of that, congratulations on your grant! I hope you’re celebrating the win!
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Is the first skirmish over? Genuinely asking.
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I would love a lawyer to clarify because it seems like there’s a considerable amount of space between the ruling and what the GOP lawyers are declaring.
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I understand that’s what GOO lawyers are saying but that’s not what the ruling actually states.
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Good tip!
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That would be no problem. Marigold can’t deal with multiple fish in a recording arena but can analyze multiple fish simultaneously if they’re in different wells.
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It’s great that you taught Down kids! I don’t work on Down Syndrome, it’s just that my last name is Downes (with an e).
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Thx. That’s my sign to go an eat a late dinner.
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📌
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I missed this earlier. Very excited to use this!
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But they could be in a multi-well plate.
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Oh, I’m sure that would be no problem. One fish at a time though!
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The name Jawsus was right there in front of them and they didn’t take it.
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Very. True.
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Hey! Megabouts looks fantastic! Looking forward to playing around with it.
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Thanks. It’s nice to have a tiny positive thing in this tsunami of bad news.
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We hope other labs find it as useful as we do! Given that it's free, we also hope it can be used in teaching labs, which are often low resourced. Congratulations to all authors! #zebrafish 🧠🧪🧬 bmcbioinformatics.biomedcentral.com/articles/10....
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While Marigold is designed for a broad range of zebrafish behavioral experiments, and we demonstrate its utility in the manuscript, we've also successfully used it for pose tracking in other species.
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Marigold doesn't require any installation and works within a variety of web browsers. Gregory Teicher, the grad student in my lab that built Marigold, developed new neural network architecture for impressive performance. This has truly been a tour de force effort by Gregory.