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giorgiaquadrato.bsky.social
Developmental neurobiologist and human organoids aficionado. Asst. Prof. @USCStemCell. Director @USC CIRM ASCEND Shared Resource Lab. Mama^2. Immigrant 🇮🇹. https://quadratolab.usc.edu/ https://ascend.usc.edu/
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Excellent 🧵 on the play-by-play arguments by the NIH v plaintiffs re: NIH cutting indirects to 15% by @scott-delaney.bsky.social - worth a read [fair warning to my US science colleagues, try not to let it get your blood pressure up, I was very unsuccessful in this regard 🥴...]

I've worked really hard to get where I am today. Stuff like this makes me feel like my very existence and effort in getting here is a threat. Why do people want to erase my identity and path? Why do people want to erase my ability to help others? It is exhausting. clarksvillenow.com/local/books-...

Thanks to all of the NIHers and their friends who reached out to me. I am still here (DM me or Signal jeremymberg.78) I still have a very incomplete picture but based on what I have been told, the damage to NIH and to many wonderful people who work(ed) there is/was impossible for me to imagine 1/n

The news won’t report on it, and the opposition won’t talk about it, but OVERT, OPEN white supremacy and neo-Nazism are the ideologies guiding the White House right. They’re not disguising it in policy, and they’re not hiding their interactions with Nazis and white supremacists.

I have been talking to the media, Time, Fortune, NBC, etc., to explain how the onslaught on science and NIH will impact the health of all Americans. Everyone knows someone who has cancer, heart disease, or depression. Spread the word about how cutting science impacts all. time.com/7216299/nih-...

Big shoutout for the #cerebellum in this excellent @cp-trendscognsci.bsky.social piece by @aniladmello.bsky.social @0xwbj.bsky.social @amandalebel.bsky.social 🧠 “Ignoring the cerebellum is hindering progress in neuroscience” (and I may add, brain evolution) www.cell.com/trends/cogni...

With critical research dollars under threat, American scientists fear a brain drain as investigators looking to start a lab consider seeking scientific refuge in potentially more stable environments - a feature w/ @jonathanwosen.bsky.social and I www.statnews.com/2025/02/12/t... via @statnews.com

"NIH admit freezing is illegal, will resume issuing grants" popular.info/p/breaking-n...

Not sure how many realize that NIH funding is still frozen. This article details an almost complete dropoff (97%) in NIH funding between Feb3-10 this year and last. Our institution's numbers are consistent with those cited here. If yours are as well, please share! popular.info/p/trump-main...

Thanks to Carolyn Johnson and colleagues at the Washington Post for covering the impact of drastic cuts to NIH on biomedical science 🧪 wapo.st/42RMXrn

Hard to describe these activities as anything other than serial arson

Noting: still up on RePORT

The NIH overhead cut doesn't just hurt universities. It's deadly to the US economy. The US is a world leader in tech due to the ecosystem that NIH and NSF propel. It drives innovation for tech transfer, creates a highly-skilled sci/tech workforce, and fosters academic/industry crossfertilization.

As the Trump Administration destroys the institutional progress we have made in diversity, equity and inclusion in science & education, each of us retains the opportunity to reflect and speak out. The piece I wrote four years ago is even more relevant today 🧪 www.molbiolcell.org/doi/10.1091/...

Preprint of our new manuscript describing the differential enzymatic and structural roles of SYNGAP1. These findings highlight the complex interplay between SYNGAP1 structural and catalytic functions in neuronal physiology and disease. www.biorxiv.org/content/10.1...

The outer ear is a mammalian innovation but where did it come from? In our study in Nature, Mathi Thiruppathy and colleagues find that the outer ear arose from modification of an ancestral gill program first originating in marine invertebrates. www.nature.com/articles/s41... 1/n

📢Call for papers. Submit your latest research to our upcoming special issue – Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues Guest Editors: Meritxell Huch and Mansi Srivastava 📅 Deadline: 15 May 2025 https://buff.ly/4iItxeg #DevBio

Delighted to highlight our new paper in @natureportfolio.bsky.social entitled 'Synaptic basis of feature selectivity in hippocampal neurons' (thread below 👇): www.nature.com/articles/s41...

Stepwise molecular specification of excitatory synapse diversity onto cerebellar Purkinje cells www.nature.com/articles/s41...

Great modeling work from @nmoris.bsky.social’s lab, shedding light on co-development between somites and neural tube. Thread 👇

So excited to share our new @natureportfolio.bsky.social review on modeling human brain development using organoids! 🧠 Loved collaborating with the brilliant @lancasterlab.bsky.social , led by the incredible @marcellabirtele.bsky.social Check it out! 🔬 #Neuroscience #BrainOrganoids rdcu.be/d3llp

Everyone knows that failure is bad. We devote a lot of time to trying to avoid it. But sometimes failure is good. A brief story: ~11 yrs ago, when my friends were all starting their own labs, I was starting my 2nd postdoc. My 1st postdoc (w/ Gord Fishell at NYU) had ended in disaster when 1/

I joined 75+ @nobelprize.bsky.social laureates urging US Senators to oppose RFK Jr.'s confirmation as DHHS Secretary. If you’re in a state with GOP senators, PLEASE reach out to them! I’d deeply appreciate it if you amplified this post! 🙏 www.nytimes.com/2024/12/09/h...

Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️ So how can we ever achieve #gender #equality? We discuss various strategies in this #Cell Commentary #WomeninSTEM www.cell.com/cell/fulltex... 🧵 1/

I participated in a faculty panel a few weeks ago in which senior (ahem) faculty gave advice on careers in academia by pretending luck had very little to do with our success. One piece of advice riled me up, in which it was argued that a reason for their success was their ability to say no. 1/

Highly recommend (long) read for anyone who's been leading a lab 10+ years!

Such a nice, comprehensive review by @marcvoo.bsky.social and @erin-schuman.bsky.social on the molecular diversity of synapses (h/t @djabaudon.bsky.social): www.nature.com/articles/s41...

Implementation and validation of single-cell genomics experiments in neuroscience - a consensus paper. Excited to contribute perturbation-based approaches. www.nature.com/articles/s41...

Human adult neurogenesis loss corresponds with cognitive decline during epilepsy progression www.cell.com/cell-stem-ce...

Transitions in development– an interview with Kara McKinley Here, @karalmckinley.bsky.social talks about her transition to becoming a PI, her insights on navigating the tenure-track market in biology and her dedication to promoting gender diversity within academia https://doi.org/10.1242/dev.204456

Cheers from the University of Utah! Thanks so much @alexshch.bsky.social for the warm welcome and great visit. Until the next adventure in the Utah mountains 😊!

We're excited to share our comprehensive protocol for generating human cerebellar #organoids, addressing the many requests we've received from the scientific community! Congratulations to Alex Atamian, @marcellabirtele.bsky.social, and Negar Hosseini! rdcu.be/d13Zu @natureportfolio.bsky.social

LAST DAY!! If you are interested in this postdoc opportunity, follow instructions on our website and send in this quick application by 11:59pm PST

“NIH produces an astounding return on investment to the American taxpayer. In Fiscal Year 2022, NIH research funding supported 568,585 jobs and generated $96.84 billion in economic activity — that’s $2.64 of economic activity for every $1 of research funding.” www.researchamerica.org/2023-oped-us...

We’re looking for a PhD student in brain onco-immunology! Apply here, one week to go: kidoktorand.varbi.com/en/what:job/...

Here is a starter pack for relevant #neuro institutions on BlueSky. go.bsky.app/LMFsego Did we forget anyone?

Great starter pack for #stemcell biologists. 😊🩵🦋 go.bsky.app/UTW4d7b

Excited to publish a broad set of enhancers to target interneuron types in the brain, along with a broad set of collaborators. Part of the BI armamentarium. Together this will help revolutionize the targeting of brain circuits.https://www.biorxiv.org/content/10.1101/2024.07.17.603924v2

Cortical interneurons learn on the job! Speculated this was true a decade ago! Sherry Wu and Min Dai finally provide evidence! www.biorxiv.org/content/10.1...