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gpollara.bsky.social
Infectious Diseases doctor (at UCLH) and academic (at UCL). Research focuses on immune responses to TB and leprosy, but I'm also involved in too many other projects I probably shouldn't be...
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Posts 16 Comments 34

Today marks the 44th anniversary of the publication in the MMWR of a new syndrome that we now know as AIDS www.cdc.gov/mmwr/preview... (MMWR 1981;30:250--2). Much progress since then but much remains to be done.

submitted 13 hours ago • 0 comments

Just dialled in. Seems like popcorn consumption on Bluesky is going through the roof tonight! 🍿 The movie that keeps on giving... #TrumpvsMusk

submitted 12 hours ago • 0 comments

this is going to end with a 150% tariff on tweeting, isn't it.

submitted 15 hours ago • 25 comments

Credit where it's due (eventually) New Outlook on Windows finally has: 1) moving emails between accounts 2) decent offline support Now I can work even more on a plane.... hmmm, now I'm not sure why I am so pleased about this change! 🤔

submitted 19 hours ago • 0 comments

Site-specific DNA insertion into the human genome with engineered recombinases www.biorxiv.org/content/10.1... in other words... genome engineering to precisely insert large multi-kilobase sequences into specific sites without introducing double-strand breaks #synbio

submitted 19 hours ago • 0 comments

Useful reminder, especially as SGLT2 inhibitors only going to become more and more common. #IDSky #ClinMicro #UTISky

submitted 2 days ago • 1 comment

the first ever @sidpharm.bsky.social and @escmid.bsky.social PK PD workshop is in full swing and it’s AMAZING so many brilliant minds in this room with the highest quality presentations #idsky #medsky #amssky

submitted 2 days ago • 2 comments

Great #FestivalofExcellence hearing superb improvement work UCLH. I talked about quality, & why spending more ≠ better outcomes. Gave 3 case studies which show drive quality ⬆️ then cost ⬇️ (hip surgery, gloves off, clinic letters). Complexity the enemy of reliability & quality

submitted 2 days ago • 0 comments

Important finding. Widespread antibiotic use, with best intentions, has long term #AMR consequences. "Azithromycin MDA is associated with macrolide resistance that persists and potentially spreads to untreated populations." #IDSky #ClinMicro #MedSky @thelancetinfdis.bsky.social

submitted 3 days ago • 5 comments

New study from @weillcornell.bsky.social and @mskcancercenter.bsky.social revealed that Bacillus Calmette-Guérin #BCG, the century-old #tuberculosis #TB #vaccine & decades-old #immunotherapy for #bladdercancer, works to reprogram immune cells in the #bonemarrow www.sciencedirect.com/science/arti...

submitted 3 days ago • 1 comment

In @elife.bsky.social: Type I interferon responses contribute to immune protection against mycobacterial infection doi.org/10.7554/eLif... #TBSky #IDSky #Immunosky work led by Gillian Tomlinson with support from @mnoursad.bsky.social & @innate2adaptive.bsky.social group (1/5)

submitted 5 days ago • 1 comment

Really informative episode for my morning commute today! Includes: - ALABAMA - safety & impact of penicillin delabelling - EAGLE-1 - gepotidacin for gonorrhoea - SOLARIO - shortening Abx for ortho infections - another trial on fosfo stepdown for UTI #IDSky #ClinMicro #UTISky @cmicomms.bsky.social

submitted 4 days ago • 0 comments

TBPod is back! Associate Prof. Nicolas Menzies joins Dr Andrew Burke to unpack the hidden burden after TB treatment, on life-years, quality of life & long-term risks. #TBPod #Tuberculosis #GlobalHealth Listen via the link below. www.buzzsprout.com/851944/episo...

submitted 4 days ago • 2 comments

New @natcomms.nature.com paper: “Unravelling the #TB lesion transcriptome & its clinical impact”! RNA-seq of 44 lesions revealed 4,630 DE genes & 17 co-expression modules linked to treatment outcomes. Huge thanks to the team & participants! 🚀 rdcu.be/eoG8F #Tuberculosis

submitted 6 days ago • 2 comments

Human LY9 governs CD4+ T cell IFN-γ immunity to Mycobacterium tuberculosis | Science Immunology Identified via a rare autosomal recessive complete deficiency in the lymphocytic surface receptor LY9 in 3 unrelated individuals with TB www.science.org/doi/10.1126/... #TBSky #ImmunoSky #IDSky

submitted 5 days ago • 0 comments

Champions League final really has become more and more like Superbowl with the big entertainment (Linkin Park) alongside the actual sporting event! #UCL #PSGInter

submitted 5 days ago • 0 comments