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grothlab.bsky.social
The Anja Groth group in Copenhagen studies chromatin replication, epigenetic memory and (epi)genome stability in the context of mitotic cell division
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๐๐ž๐ฐ ๐ฆ๐ž๐œ๐ก๐š๐ง๐ข๐ฌ๐ญ๐ข๐œ ๐ข๐ง๐ฌ๐ข๐ ๐ก๐ญ๐ฌ ๐ข๐ง๐ญ๐จ ๐ญ๐ก๐ž ๐ซ๐ž๐ ๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐จ๐Ÿ ๐ก๐ข๐ฌ๐ญ๐จ๐ง๐ž ๐ฌ๐ฎ๐ฉ๐ฉ๐ฅ๐ฒ! Excited to share our latest collaboration led by tkjeong.bsky.social and ciaranfrater.bsky.social! Structural determination of the histone chaperone ASF1 and its regulator CODANIN-1 uncovers how CODANIN-1 counters ASF1 activity. ๐Ÿงต๐Ÿ‘‡

SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026. ย  Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute). www.embl.org/about/info/c...

Epigenetics Gordon Research Conference. Consider joining us for what will be an excellent, exciting meeting and will be held in Europe for the first time: 10-15 Aug25 Barcelona, Spain. Please repost and apply early - this meeting is popular! www.grc.org/epigenetics-...

I am delighted to share the main work of my PhD project in the @hamperllab.bsky.social now out in @narjournal.bsky.social. TRCs drive R-loop-dependent nucleosome eviction and require DOT1L activity for transcription recovery. academic.oup.com/nar/article/... #TRC #r-loop #chromatin More below ๐Ÿ‘‡

๐‡๐จ๐ฐ ๐๐จ ๐œ๐ž๐ฅ๐ฅ๐ฌ ๐ซ๐ž๐ฆ๐ž๐ฆ๐›๐ž๐ซ ๐ฐ๐ก๐จ ๐ญ๐ก๐ž๐ฒ ๐š๐ซ๐ž ๐š๐Ÿ๐ญ๐ž๐ซ ๐ƒ๐๐€ ๐ซ๐ž๐ฉ๐ฅ๐ข๐œ๐š๐ญ๐ข๐จ๐ง? Our new study โ€œDisabling leading and lagging strand histone transmission results in parental histones loss and reduced cell plasticity and viabilityโ€ is out in ๐˜š๐˜ค๐˜ช๐˜ฆ๐˜ฏ๐˜ค๐˜ฆ ๐˜ˆ๐˜ฅ๐˜ท๐˜ข๐˜ฏ๐˜ค๐˜ฆ๐˜ด. Led by @lleonie.bsky.social @biranalva.bsky.social ๐Ÿงต More below๐Ÿ‘‡

๐Ÿšจ๐Œ๐š๐ฃ๐จ๐ซ ๐‰๐จ๐› ๐€๐ฅ๐ž๐ซ๐ญ!๐ŸšจThe Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring ๐Ÿ” ๐๐ก๐ƒ&๐ฉ๐จ๐ฌ๐ญ๐๐จ๐œ๐ฌ to join the new Center for Epigenetic Cell Memory (EpiC)ย in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!

Do not miss out on this webinar on @bio-protocol.bsky.social to see what we have been up to in quantifiying single cell DNA replication dynamics using scEdU-seq ! ๐Ÿš€ Register now! bio-protocol.org/webinar/deta...

Just over the moon that the grant, wrote with my amazing long-time friend @lleonie.bsky.social, has been funded by @novo-nordisk.bsky.social for an incredible โ‚ฌ2M! ๐Ÿคฏ Huge thanks to Alexander and @grothlab.bsky.social for their support and guidance throughout. Thrilled for the journey ahead! ๐ŸŽ†โœจ

Exciting news!๐ŸŒŸ Together with Alexander van Oudenaarden, @jervdberg.bsky.social and @lleonie.bsky.social, weโ€™ve been awarded a โ‚ฌ2M NNF Synergy grant. We're thrilled to collaborate๐Ÿค and to develop cutting-edge single-cell and single-molecule methods for replication and chromatin research! ๐Ÿš€

This is a reminder that there is still space in this starter pack if you want to join ๐Ÿคฉ. Just send us a message!