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heiman.bsky.social
Associate Professor of Genetics Harvard Medical School, Boston Children's Hospital It should be fun, or what's the point? http://heimanlab.com
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Thanks for the shout out @meera-sundaram.bsky.social ! This was such a fun project! 101 knock-ins and counting and they all had such cool and unique localization pattern and substructures!

Delighted to share this timely article in Boston magazine on our local C. elegans community and the effects of NIH freezes. "There might be no group more enthusiastic, self-aware, or life-affirming than the worm people." www.bostonmagazine.com/news/c-elega...

Write a horror story in ten words.

This tops everything. Is there a short history anywhere of why everyone chose their allele/strain designations?

👇👇👇 New preprint dropped! Where we dive deep into the factors that restrict pluripotent stem cells to make the RIGHT cell types in the RIGHT place in planarians. Many surprises in this very exciting story. @kuangtse.bsky.social

photo from lab tonight, courtesy of grad student Jung Hyun Yoo

the big question

watching squirrel tv

this is getting ridiculous (in a good way). first it's $15 plasmid sequencing, now it's $25 C. elegans genome sequencing. time to look through our freezer collection at all the mutants we never followed up...

you can't go wrong studying ZP domain proteins!

NLM support responded within 30 min! Known issue that will be addressed in future update.

SciENcv question - I am required to create a biosketch using SciENcv. I can format section headers, lists, and italics using its markdown language on screen. But when I download the biosketch as PDF or Word, the formatting is lost and the raw markdown characters (# or *) are shown. Any ideas?

Thinking about Terry Gilliam's "Brazil" today for no particular reason youtu.be/wzFmPFLIH5s?...

How does the sense of smell influence behavior? 🧠👃 Surprisingly, research in the model system - C. elegans - shows the chemosensory system plays a key role in decision-making 👇Watch the full episode @dougp.bsky.social & @johnfoxe.bsky.social urmc.info/1XY #BrainAwarenessWeek #URochesterResearch

Happy 29th to us! Celebrating 29 yrs of NIH & NSF funding, which has advanced our understanding of sensory transduction & processing in health & disease, trained 70+ students/PDs—now physicians, scientists, writers, teachers & more—and boosted the economy by purchasing supplies. #StandUpForScience

I need a new assistant, this one has an attitude and his emails make no sense.

The megakaryocyte: trapped in a cage of its own making 𐂺 In this #preprint, @wclairemasson.bsky.social & colleagues report the discovery of novel structures controlling megakaryocyte protrusion events. Excellent #preLight from @simoncleary.bsky.social ⬇️ 👀 prelights.biologists.com/highlights/m...

I was looking for something in (very) old emails and came across this uplifting note from Ben Barres not long after starting my lab: " The first 5 years are tough! Gets easier after tenure. By the time you are an old fart, things are the best!! :-) "

I've been wondering how much longer we can continue to use "hermaphrodite" in our C. elegans grants and papers.

When a reporter asks to talk, the answer is YES. Thank you @clewisreports.bsky.social "Maureen Barr runs a lab at Rutgers University in New Jersey...Barr, like many scientists across the region and country, is now worried about her lab’s future..." gothamist.com/news/ny-nj-j...

@jeremymberg.bsky.social thank you for your explainer posts. If you take requests - would you please summarize what powers the NIH director has? My memory from Varmus's book was that they can mostly appoint commissions & most power is with institute directors, but recent news seems to run contrary.

I have not seen a crisis of this magnitude since yesterday

this is like forensics but for #cilia... pmc.ncbi.nlm.nih.gov/articles/PMC... @bungoakiyoshi.bsky.social so one question is - do the two flagella beat differently in Diplonema?? (feel free to send us some to take a look!)

What makes biological systems different from chemical systems is that they don't minimize free energy, but instead constantly consume energy to build and propagate ordered and absurdly improbable states. Therefore all biology is developmental biology. (Also all biology is structural biology.)

🧪Very proud of our latest publication at @elife.bsky.social, brought to you by #NIH funding! This collaboration with Chris Rongo's lab covers a lot of ground, focusing on the transcriptional response to BMP/Smad signaling. 1/n doi.org/10.7554/eLif...