hlatim.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Given the sea change in science funding, policy and public disinterest - the center of gravity in biomedical science will likely shift in the coming years ! Hopefully freedom of expression and reporting of truth will not change... #VERITAS www.nature.com/articles/d41...

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The US research ecosystem, the crown jewel of the world, is systematically getting destroyed. Will the public stand idly by? www.usatoday.com/story/news/p...

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Less than a week to go… if you haven't registered for this month's #webinar, titled: ‘Biology and therapeutic approaches of sphingolipid chaperones and receptors’ with Timothy Hla (@hlatim.bsky.social), you can register here: bit.ly/3FeiBpT

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June 12th is Loving Day, a holiday that commemorates the Loving v. Virginia case, which allowed interracial marriage in all parts of the U.S. NPR readers share how the case changed their lives.

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#VitaminE_FriendOrFoe?! Garcia-Bermudez &co show @nature.com that tumors uptake lipoproteins enriched in Vitamin E protecting cancer cells from ferroptosis! Identification of sulfated glycans as port of entry of lipoproteins can be used therapeutically to force tumor ferroptotic cell death!

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What Happens if ‘Harvard Is Not Harvard’? www.nytimes.com/2025/06/11/u...

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Can the U.S. Be a Great Power Without Harvard? - Foreign Policy

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Absolutely this 👇

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“You can get a other job, but you cannot get another soul”.

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Important study which shows HDL delivery of cholesterol to steroidogenic and bile producing tissues requires S1PR signaling - synaptotagmin is a key mediator rdcu.be/eosqR @natcellbio.nature.com

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Time for blumens! La primavera …

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www.thecrimson.com/article/2025...

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www.linkedin.com/posts/harvar...

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supported 407,782 jobs and $94.58 billion in new economic activity nationwide, the largest figure in the history of the report. That translates to a return on investment of $2.56 for every $1 in awards.

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Another serious contender for this year's bad idea olympics: www.nih.gov/news-events/.... Animal models provide the ground truth for any high-tech approach for studying disease and for most of translational medicine. Without animals, we'll quickly lose contact with reality.

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At least 2,500 applications for research funding have been denied so far this year, more than double the previous two years https://go.nature.com/4dynTcw

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We need a new model for funding -create a miniNIH funded by stakeholders- see #7 by Marks! www.nytimes.com/2025/05/19/o...

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How Type 2 diabetes leads to blood vessel dysfunction and sequelae related to this adverse effect @jclinical-invest.bsky.social jci.org/articles/vie...

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Want to live a longer and better life? Give creative people resources to make your life better. Harvard.edu

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The 80-year recipe stoking America’s Prosperity: 1) Free-market capital investments in brilliant ideas… 2) enabled by Engineering Innovations… 3) based on Science Research in Universities… 4) funded by Grants from the US Government. It’s time more people understood this.

submitted 34 days ago • 387 comments

Urgent call for action to patient advocacy groups, Massachusetts pharma/biotech/VC leadership and the public concerned about biomedical research advances!

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Existential crisis for HMS, FAS and HSPH faculty, students and staff due to US Government funding cuts - if the pharmaceutical, biotech and VC communities value the contributions of the Harvard Biomedical ecosystem, the time is now to PITCH IN and SUPPORT research www.thecrimson.com/article/2025...

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Must read for everyone concerned with the health, prosperity, and global leadership of America

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The Trump administration this week eliminated funding for Harvard research projects across a host of areas, from the origins of breast cancer and the impact of nutrition on fertility to antibiotic resistance.

submitted 34 days ago • 37 comments

NIH-funded basic research allowed me to discover two molecules (COX-2 and S1PR1) that became drug targets - COX-2 inhibitors and S1PR modulators - more than 7 million prescriptions for Celebrex taken for pain; >350k people have taken Fingolimod/Ozanimod for MS and IBD/UC-basic research is essential!

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9 Federally Funded Scientific Breakthroughs That Changed Everything www.nytimes.com/2025/05/16/s...

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Kennedy to Defend H.H.S. Overhaul as Democrats Denounce ‘War on Science’ www.nytimes.com/2025/05/14/u...

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The World Is Wooing U.S. Researchers Shunned by Trump www.nytimes.com/2025/05/14/b...

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The NIH has dropped its research funding by $2.7 billion so far this year. Cancer research funding has declined 31%. And new NIH research grants fell to the lowest level in more than a decade. Eye-opening findings in today's HELP committee minority report: www.sanders.senate.gov/wp-content/u...

submitted 38 days ago • 7 comments

Europe Makes a Pitch to Attract Scientists Shunned by the U.S. www.nytimes.com/2025/05/05/w...

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Sphingolipids needed for NK and cytotoxic T cells - superenhancers to the rescue! www.sciencedirect.com/science/arti...

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Opinion | American higher education is collapsing before our eyes - The Guardian

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Public Media Giving Days are here! ❤️🖤💙 The NPR Network makes trustworthy journalism, music, and unforgettable stories available to nearly 99% of the U.S. population–free of charge. It's time to show your love for how much #PublicMediaGives your community. Donate here: n.pr/4lFTPPD

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magazine.hms.harvard.edu/articles/tra...

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Deaths from heart disease down 75%, that’s NIH. Deaths from stroke down 75%, that’s NIH. HIV/AIDS no longer a death sentence, that’s NIH. 99% of FDA approved drugs in the last decade, that’s NIH. Please show this video to anyone who doesn’t understand why the NIH is so important.

submitted 52 days ago • 60 comments

Here is a link to 60 Minutes NIH segment... www.cbsnews.com/news/scienti...

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www.cbsnews.com/news/scienti...

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#WeekendRead! #NotAllLipidsAreEqual! Glogowska, Honore &co show @cp-cellreports.bsky.social that oxLDL potentiates, while omega3 inhibits, mechanosensing signaling via Piezo1 by altering plasmamembrane cholesterol, favoring #atherosclerosis!

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“Cell surface RNA biology: new roles for RNA binding proteins” Jennifer Porat and I discuss this new cellular topology on which to study RNA–RBP interactions and consider how changes in the csRBPs may drive autoimmune responses. @cp-trendsbiochem.bsky.social www.sciencedirect.com/science/arti...

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Latest paper from the lab spearheaded by Bongnam Jung - ApoM-Fc as a potential therapeutic for neovascular AMD - link.springer.com/article/10.1...

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NIH cancels its first and largest study centered on women www.science.org/content/arti...

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magazine.hms.harvard.edu/articles/bri...

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My quote of the day Facts are the air of scientists. Without them you can never fly. Linus Pauling

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J Clin Lipidol, 2025 S1933-2874(25)00067-4 Ceramide levels positively correlate with systolic and diastolic blood pressure, and ratios of Cer relative to Cer(d18:1/24:0) suggest an increased cardiovascular risk. - www.ncbi.nlm.nih.gov/pubmed/40263...

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Could Trump's War on Harvard Spell the End of U.S. Leadership in Science? www.medpagetoday.com/opinion/seco...

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www.amjmed.com/article/S000...

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Did S1P chaperones and receptors evolve to regulate stress response in invertebrates? The elegance of C. elegants! Intercellular sphingolipid signaling mediates aversive learning in C. elegans: Current Biology www.cell.com/current-biol...

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"Science in the US is entering a phase resembling the Lysenko era in the Soviet Union." www.theguardian.com/commentisfre...

submitted 71 days ago • 13 comments

I love taking photos of blood vessels in the brain! Here are some of my favorite shots, which one resonates with you the most? #MicroscopyMonday

submitted 73 days ago • 12 comments