Profile avatar
isbscience.org
Institute for Systems Biology, 501(c)3, pioneers of systems biology. Affiliate of Providence. Stay up-to-date at http://isbscience.org.
60 posts 188 followers 143 following
Prolific Poster

Great conversation on the #AI Revolution last week featuring Craig Mundie and @isbscience.org President Jim Heath! Recap and video available: isbscience.org/news/isb-eve... @townhallseattle.bsky.social

Is cancer solely genetic? 🤔 Join @isbscience.org's Dr. Sui Huang TOMORROW (5/14, noon PT) for a FREE virtual event challenging the dominant view. Register here, and please share widely! give.isbscience.org/research-rou...

Many thanks to the 25 donors who helped us reach the finish line and unlocked the $2,500 challenge match for #GiveBIG! You have made an important impact on our groundbreaking #research and vital #STEM programs – THANK YOU!

We only have until midnight tonight to reach our goal and unlock a $2,500 challenge gift! Your #GiveBIG donation today could be the one to drive us over the finish line, powering vital #research and #STEM #education when it matters most. GiveBIG today at www.wagives.org/organization...

May 6-7, YOU can make an impact with an @isbscience.org gift supporting #research & #STEM education at a critical time. Celebrating our 25th anniversary: The first 25 donors to #GiveBIG will unlock a $2,500 challenge gift from an anonymous staff member. GiveBIG today! www.wagives.org/organization...

#GiveBIG is May 6-7. This year your support is more important than ever. Proposed changes to NIH funding policies threaten the critical infrastructure that powers lifesaving research. At @isbsci, we’re pushing forward – but we need your help. Early giving is open! mtyc.co/w0o1ze

We are saddened to share the passing of Valerie Logan Hood, beloved wife of ISB Co-founder Dr. Lee Hood. Valerie’s dedication to K-12 education shaped ISB’s education programs & and her influence continues to be felt by students and educators in WA state and beyond. isbscience.org/news/philant...

RESEARCH | @cdiener.com @gibbological.bsky.social et al. ( @isbscience.org @medunigraz.at ) Estimation of dietary intake from human stool by detecting food DNA in faecal metagenomes💩🧬 https://bit.ly/3YphSbw ?utm_source=bluesky&utm_medium=social&utm_campaign=natmetab

This Friday, 11:30-1 and in-person, @isbscience.org's @alicekane.bsky.social will present The Biology of Aging: Bridging Frailty and Health Outcomes, offering insights into how aging affects health & function. Register: www.eventbrite.com/e/2024-2025-...

This @pnas.org Journal Club post highlights recent work published in @cellpress.bsky.social' Cell Systems by Drs. Wei Wei, Jim Heath, and colleagues that showed how skin cancer cells develop resistance to vemurafenib, a BRAF inhibitor that targets melanoma. www.pnas.org/post/journal...

Drs. Carl Murie, @nitinbaliga.bsky.social, and collaborators have developed a powerful new tool called mmSYGNAL that could transform how doctors treat multiple myeloma, a complex and often unpredictable blood cancer. isbscience.org/news/cancer/...

In the March installment of the 2024-25 academic year roundup, we highlight how ISB educators have been active in the local community, and much more. isbscience.org/news/educati...

#AI is reshaping our world. What does it mean for healthcare, discovery & human potential? On 5/7 @isbscience.org's Jim Heath sits down with Craig Mundie, co-author of "Genesis: Artificial Intelligence, Hope, and the Human Spirit," at @townhallseattle.bsky.social. townhallseattle.org/event/craig-...

Great interview with @gibbological.bsky.social talking about poop frequency and how it can affect human health. The Excerpt is the flagship podcast of @usatoday.com. Congratulations to Sean and the Gibbons Lab on the continued interest and reach of this research!

In this week's oncology-focused newsletter, Inside Precision Medicine details work by @isbscience.org & @mitofficial.bsky.social showing how #melanoma cells can evade #cancer drugs shortly after treatment & how combination therapy can improve outcomes. www.insideprecisionmedicine.com/topics/oncol...

In a provocative new essay published in @plosbiology.org, @isbscience.org Professor Sui Huang and colleagues argue that the prevailing view of #cancer as a purely genetic disease needs to be rethought. isbscience.org/news/cancer/...

Microbiologist & ISB Associate Professor Dr. @gibbological.bsky.social was a guest on The Last Show with David Cooper. Sean talked about research out of his lab detailing poop frequency and its impact on our health. The interview starts roughly at the 20-minute mark. open.spotify.com/episode/1Oup...

Curious about the gut microbiome & its impacts on sleep throughout the adult lifespan? 🦠😴 You're in luck! @isbscience.org PhD student Jacob Cavon led a review of this topic for the @amiposts.bsky.social journal Letters in Applied Microbiology (just accepted): academic.oup.com/lambio/advan...

Thank you Vice News for covering my team and I’s research on bowel movement differences in healthy adults and the impact during my doctoral study at the @isbscience.org & @uwseattle.bsky.social with Prof Sean Gibbons at @gibbological.bsky.social Enjoy the article! www.vice.com/en/article/w...

Drs. Wei Wei, Jim Heath and colleagues from @isbscience.org and @mitofficial.bsky.social show how melanoma cells use a stealth survival strategy to evade targeted therapy and how combination therapy can improve outcomes. @cp-cellsystems.bsky.social www.sciencedirect.com/science/arti...

In an essay in the journal @plosbiology.org, @isbscience.org Professor Sui Huang, MD, PhD, and colleagues say it's time for researchers to reconsider the current paradigm of #cancer as a genetic disease. www.news-medical.net/news/2025031...

BrainFest at the Pacific Science Center rocked! 🧠 ⚡️ 🤘 Thank you to all the young scientists who joined our cerebral celebration and all the volunteers, including from our partners at @uwmedicine.bsky.social, @uofwa.bsky.social, @isbscience.org, and many more! #BrainAwarenessWeek #brainfest

Happy Pi Day from all of us at ISB! We celebrated by having pie 🥧 and a contest to guess how many decimal places were shown on a large poster of Pi. Spoiler: It shows over 67,000 decimal places! #PiDay2025

We’re participating in BrainFest this Saturday at the Pacific Science Center with a highly interactive and visual activity called “Blood Brain Barrier Breakout”. We hope to see you there!

Always a good day when your main funder highlights your latest work! 💩➡️ 🍌🥦🥩🥑 #NIH #NIDDK #microbiome #diet @cdiener.com @isbscience.org www.nih.gov/news-events/...

Wow! Work by @gibbological.bsky.social and the Gibbons Lab is featured in BBC News! Congratulations, team!

Wow, just finished reading the @microbiome.bsky.social lab's preprint on how gut flagellin levels influence vaccine responses. www.biorxiv.org/content/10.1... In the paper, they leverage our MEDI tool (estimating dietary in take from fecal DNA) to come to a really surprising conclusion! 🧵...

For my francophone friends out there, our MEDI paper (predicting diet from poop DNA) was covered on Radio-Canada yesterday: ici.radio-canada.ca/ohdio/premie... @cdiener.com @medunigraz.at @isbscience.org @natmetabolism.bsky.social

A new way to measure your food intake, from your 💩 www.nature.com/articles/s42... www.nature.com/articles/s42... "proof-of-concept for detailed tracking of individual-specific, health-relevant dietary patterns without the need for questionnaires."

Introducing "Metagenomic Estimation of Dietary Intake", or "MEDI": a data-driven approach to estimating dietary and nutritional intake from stool DNA 💩 - 🍌🥦🐟🥩📈 See @cdiener.com's excellent thread below. We are really proud of this work, and we hope it is useful to the scientific community.

🚀 We're Hiring: Contracts Specialist! 🚀 Join @isbscience.org's Legal & Innovation team (Seattle, Hybrid) to manage contracts, NDAs, & licensing for cutting-edge research. 🔹 2+ yrs contracts/paralegal experience required 📌 Apply at isbscience.bamboohr.com/careers/42 Boost or tag a great candidate!

Predicting out a T cell will behave: New research out of Jim Heath's lab at @isbscience.org uncovers hidden rules of immune response, opening doors for better vaccines and immunotherapies. @naturecomms.bsky.social www.nature.com/articles/s41...

🚨 We're Hiring! @isbscience.org is looking for a Health & Safety Specialist to lead lab services operations & oversee health & safety programs in a dynamic research environment. Join us & make an impact! Apply here: isbscience.bamboohr.com/careers/41?s... #Hiring #HealthAndSafety #LabJobs

Dr. Lee Hood spoke with Nick Jikomes on the @mind-and-matter.bsky.social #podcast. Topics discussed: systems biology, big data, #AI integration, drug development & more. The episode is available below & on Apple, Spotify, YouTube, etc. mindandmatter.substack.com/p/systems-bi... @buckinstitute.org

What orchestrates the dance of innate immunity? Lauren Spector and I reflect on how the NLRP3 inflammasome dynamically interacts with organelles to coordinate immunity—thanks to the remarkable work of researchers in the field! journals.lww.com/immunometabo...

We are heartbroken by the passing of Ginny Ruffner, a beloved artist and passionate advocate for ISB. Her art inspired us, her advocacy lifted us, and her legacy will live on. Read more: www.seattletimes.com/entertainmen.... Donations can be made to SOLA (Support Old Lady Artists): solaseattle.org.

🚨 New insights on #LongCOVID & genetic risk from @isbscience.org President Dr. Jim Heath. In this short video clip, he explains how genetic factors could help us separate nature from nurture in Long COVID research. 🎥 Watch the full video here: isbscience.org/news/infecti... youtu.be/nLkfOK-yH6c

Check out this amazing preprint from my @isbscience.org colleague @annabiosys.bsky.social's lab! Gupta et al. captured the entire infection cycle of an uncharacterized phage through single-cell RNA-seq of a B. fragilis population (capturing cells at different points in the infection cycle). 🤩

🌟 Big News: ISB’s New Website is Live! 🌟 We embrace the full complexity of systems biology to tackle challenges across multiple domains. 🔗 Explore the new site and learn how you can make an impact: isbscience.org

#LongCOVID is real. Millions of people who had #COVID19 still have symptoms lasting months or even years. Tomorrow at 6pmPT, leaders of the PNW Consortium of the RECOVER Study will give an update on the project. Join us – it's free. Register here: us02web.zoom.us/webinar/regi...

Congratulations to ISB Board Member Craig Mundie on "Genesis: Artificial Intelligence, Hope, and the Human Spirit," the bestseller he co-authored with Eric Schmidt and Henry Kissinger. Craig sat down with Sam Altman for the following conversation: www.youtube.com/watch?v=Z246...

Check out the first publication from the Kane lab @isbscience.org! RNAseq analysis of sex differences in aging across tissues - spoiler alert - there are lots of them! bsd.biomedcentral.com/articles/10.... Congratulations and thans to @dantong-zhu.bsky.social, @judywbio.bsky.social & other authors.

In our latest preprint, led by Master's student Gechlang Tang, we put forth a modest proposal: why not just use host-derived reads as a normalization factor for estimating absolute bacterial biomass in stool metagenomes? 🦠💩📈 @isbscience.org www.biorxiv.org/content/10.1...

Join us 1/15 from 6-7pm PT. Drs. Jim Heath, Jason Goldman & Helen Chu will provide updates on the RECOVER study and plans for RECOVER 2.0. Study coordinators Allie Duven & Helen Nguyen will address common questions, & audience members can submit questions during a live Q&A. https://buff.ly/4h8doNF

Last call! Tomorrow is the final day to make a gift to @isbscience.org and have your donation matched dollar-for-dollar! Your contribution fuels the work of our brilliant researchers and educators, helping turn bold ideas into real-world solutions. Make your gift today at give.isbscience.org.

Wishing you joy, warmth, and cheer this holiday season and a bright, prosperous 2025!

Great year for @gibbological.bsky.social and the Gibbons Lab!