jfreemandaily.bsky.social
Lung cancer patient and research advocate. Cofounder #LCSM Chat, The ROS1ders, IASLC STARS. Also writer, retired engineer, science geek. Temporarily between feline overseers. Blog at grayconnections.net.
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1,649 followers
1,912 following
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Musk's approach to reducing the federal workforce is already showing significant negative consequences. I wish we could learn from history. 4/4
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Now DOGE is indiscriminately firing groups of people without considering whether they have essential expertise. DOGE is discovering that it's difficult to recover essential expertise such as people staffing the nuclear arsenal and tracking bird flu developments. 3/4
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Many people happily took the deal--so many in fact, that Boeing suddenly discovered it had lost significant expertise. The damage to Boeing's capabilities was evident. A number of friends who took the deal were invited back as contractors so the company could retain essential expertise. 2/4
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Edit to add: Only one of the five has died. Apologies for the misinformation!
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It's rewriting a hypothetical journal article, not a grant application. For demonstration purposes only.
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Thanks. And yes, so sad that the USA's world-class science/medical infrastructure and workforce is being randomly decimated.
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Even though the [women] participants with 2 X chromosomes responded better, the lack of [diversity] differences in genetic, genomic, and epigenetic characteristics in the study population means the results cannot be applied to people in general. 3/3
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Half of the group was male, the other half [was female] had two X chromosomes. The results may be [biased] tilted because all participants lived within one mile of the Major Cancer [Research] Analysis Center. 2/3
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@jfreemandaily.bsky.social our first #ayacsm #OncSky #MedSky #SkyChat is tomorrow! Please follow back and spread the word! #Rebuilding
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Thanks!
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Yes @dhendrickson.bsky.social we both know many people who are living with #lungcancer for 10+ years thanks to targeted therapies and immune checkpoint inhibitors (including me). Alas, not many who are receiving only chemo for lung cancer live 10+ years. #LCSM
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Why should anything less than a grade 3 toxicity be considered acceptable and why, when grade 1 and 2 toxicities can be so different, are they grouped?
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The need to remedy this approach has been percolating in several tumor types and I urge colelagues to replicate this simple analysis in their disease type and track it over time and publish it.
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It's true that forest plots often show results for small subgroups. However, as you know, when analyzing trial results for a rarer lung cancer like ROS1+, data from small subgroups is often all we have.
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Sorry, it looks similar to a forest plot. That's what I was thinking of.
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For me the tornado plot gives a quick impression of which populations may or may not respond. Displaying the bars side-by-side facing the same direction takes me more time to decipher. #oncsky
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Hope you know where your towel is!
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Thanks Stacey!
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Not that I can see, but I'm still learning.
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Don't know. You could search for one with hashtags like #CRCSM or #ColorectalCancer, or check accounts of clinicians and/or advocacy groups (like @fightcrc.bsky.social )