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jmriph.bsky.social
Instructor @ MGH Martinos Center/Harvard Medical School. Likes neuromodulatory systems. 🇩🇪/🇳🇱trained Anesthesiologist / CC MD / Neuroscience PhD.
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Rummaging under the hood of the Silent Bobx relay/randomizer box for neuro stimulation with a pico scope. Now waiting for 25cts worth of parts to fix a suboptimal design decision, that is making the Cortex M4 board intermittently unhappy after a while. #Science #alzheimer #prototyping

National pangolin day ! advanced bar trivia: The tree pangolin is the only vertebrate which doesn’t have an LC (no A6)! It sort of moved NE neurons to the sub-coeruleus but runs dendrites to empty A6 site, that kept normal neurochem relations (ORX/Ch/5HT) onlinelibrary.wiley.com/doi/10.1002/...

"The Locus Coeruleus: Blueprint Towards Identifying Preclinical Alzheimer’s Disease" www.youtube.com/live/SYXJ83-... there’s another doctor in the house. 🎉🎉🍾 ! Congratulations Nina !

Back from 🇵🇷 to Boston. Quite the contrast.

2nd day of hitting the memory buffer @HAI2025 Inspiring keynote from @leatgrinberg.bsky.social

Postponed it as long as I could but compliance requirements have caught up. All appendages crossed.

New work from our postdoc Elouise Koops just got published: #locuscoeruleus metabolism is elevated in preclinical Alzheimer’s disease, and provides resilience against cognitive decline! In collaboration with Joyita Dutta (UMass) alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Ready to smoke test Silent BObX MkII Neuro stimulation SSR /randomization sham/stim box. Now I will find out if the ‘it looked larger on the spec sheet’ (quarter for size) zener diode d1 is in the right direction because I can barely see the 🤬 thing . #prototyping #alzheimer #RAVANS

Day 3 of figuring out where these artifacts come from. Hey I think I found it! v28.0

X-> “Why' is the only question that bothers people enough to have an entire letter of the alphabet named after it” Douglas Adams