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joaoftsbotelho.bsky.social
CEEC Researcher at UCP 🇵🇹 Before: Maria Zambrano fellow at CBGP 🇪🇦 and postdoc at Max Planck Institute for Evol Biol 🇩🇪 @schulenburglab.bsky.social MGEs, AMR, defense systems, HGT. https://scholar.google.com/citations?user=_Sz69QgAAAAJ&hl=en
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An ICE, a PICI, and a phage walk into a cell… and start crosstalking. Interesting read on how MGEs juggle interactions like pros! 🦠 academic.oup.com/ismej/articl...

Excited to share that this preprint is now published @genomeresearch.bsky.social! 🎉 Check it out here: genome.cshlp.org/content/earl...

🚨PhD studentship opportunity! Bacteria protect themselves with a huge arsenal of defences, but does this affect how they gain new traits on plasmids? 🧫🦠💫 Apply for a funded 4y position with me @livuni-ives.bsky.social, @brockhurstlab.bsky.social @jojofoth.bsky.social & @multidefence.bsky.social ⬇️

Bonnie and Clyde phages 😎

Delighted to share the first peer-reviewed paper from our team @camvetschool.bsky.social where we investigate the ecological dynamics of Enterobacteriaceae in the human gut #microbiome: www.nature.com/articles/s41... @naturemicrobiol.bsky.social

Joy! Published today in PNAS: multi-toxin T6SS attacks limit resistance evolution in competitors! Big thanks to our wonderful team of collaborators for all their help: @coytelab.bsky.social @knightjar.bsky.social @basler-lab.bsky.social @brockhurstlab.bsky.social 🎉 www.pnas.org/doi/10.1073/...

What is the diversity of antiphage systems out there ? We used protein and genomic language models (and defense score!) to start bringing some answers: >45 000 protein families. Leb by E. Mordret. www.biorxiv.org/content/10.1... Interactive UMAP to have fun mdmparis.github.io/antiphage-la...

Very excited to have this paper officially out. This one is pretty special... Unfortunately, @kevinwoodum.bsky.social passed away when this paper was in its final stages. He was my biggest supporter, and I miss him deeply as a mentor and friend.

Our review is out in Nature Reviews Genetics! rdcu.be/d5AY2 We show how phylogeny-based methods can resolve the problem of non-independence in genomic datasets. These methods must be considered an essential part of the comparative genomics toolkit. @lauriebelch.bsky.social @stuwest.bsky.social

We are happy that our work has finally been accepted for publication at @genomeresearch.bsky.social! Link to follow soon #MicroSky

New year, new beginnings! 🎉 The Aviram Lab will officially open its doors on March 1st @mskcancercenter.bsky.social! We’ll study microbial immune systems and their connection to fundamental cellular processes like #RNA transcription and #DNA integrity. #NewPI #AcademicSky #WomenInSTEM (1/2)

Sharing three fully funded PhD opportunities to join my lab at Queen’s to work on topics spanning bacterial pathogens, antibiotic resistance, microbial interactions, & mobile genetic elements 🦠. Closing dates in January and February, and open to international candidates 🌍 Projects detailed below ⬇️

Nice study from @annechevallereau.bsky.social's lab! www.biorxiv.org/content/10.1...

🚨 PhD opportunity 🚨 The Whelan lab, @jojofoth.bsky.social, & @brockhurstlab.bsky.social are looking for a PhD student w micro experience to study how commensal bacteria modulate the virulence of P. aeruginosa using a fly infection model. More info & link to apply below. Please spread the word!

Out in NAR, AntiDefenseFinder & our "systematic" analysis of inhibitors of antiphage systems wt Bondy-Denomy lab led by @ftesson.bsky.social and E. Huiting. Not so "systematic" as very few known, fun stuff on MGE, antidefense islands and cool phages exaptations! academic.oup.com/nar/advance-...

A new #StarterPack with scientist specialized in microbial bioinformatics - #MicroBioInf. Please comment if you would like to be added: go.bsky.app/5h7VaGm Looking forward to the discussions!

Chromosomal plasticity can drive rapid adaptation in bacteria by @mtoll8.bsky.social's lab www.biorxiv.org/content/10.1...

Deadline in ‼️3 weeks‼️ for this project with me & @paulhoskisson.bsky.social 🦠 🧫

Interesting paper showing how miniature inverted-repeat TEs (MITEs) can be used as a method to link microbial hosts to their viruses. Cool!

Starter pack for metagenomics and microbial genomics lovers. go.bsky.app/MFipoLH

Hello 🦋 #protein / #microbio / #BioML community! We are excited to release Gaia🌎, a context-aware protein search tool, extending protein search and discovery capabilities beyond sequence and structure, to include *genomic context*. Search your favorite protein sequences with on gaia.tatta.bio

Diversity-generating retroelements for the win!