johannes-uni-wue.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Anyone interested in using mass spectrometry to identify and quantify peptides and proteins in plasma, tissue and organoid cell systems? I have a Research Assistant position in my lab at the Institute of Metabolic Science - Metabolic Research Laboratories. Apply here: lnkd.in/dCxhS3GN

submitted 7 days ago • 1 comment

Update of our protein outlier caller PROTRIDER. We now handle missing values, a widespread issue for mass spec where missing values are not a random -- and this improves outlier detection on non-missing data! Thumbs up to Daniela and George for the great work. doi.org/10.1101/2025...

submitted 14 days ago • 0 comments

🚀 We're launching quantms.org — new hub for all #quantms related projects. Explore its components #pmultiqc & #ibaqpy, and check all reanalysis we're sharing with the community: quantms.org/datasets Meet the Team and Labs behind the project 👉 quantms.org/about #OpenSource #Proteomics #ASMS2025

submitted 16 days ago • 0 comments

Almost intentionally, looks like all of the new Thermo instrument pages are up (Astral Zoom, Excedion Pro, Optispray). Overall vibes? Excedion is the bigger upgrade, almost 2x faster and can now do ETD. Astral Zoom improvements are more incremental. No change to instrument sensitivity specs.

submitted 22 days ago • 4 comments

Very excited that another chapter of my PhD is finally out! 🎉 We compared methods to infer kinase activities from #phosphoproteomics data so check it out if that sounds interesting to you. More details in the thread below 🧵👇🏼

submitted 24 days ago • 0 comments

🚨Our new paper is online🚨 We use zero-distance⚡photo-crosslinking⚡to reveal direct protein-DNA interactions in living cells, enabling quantitative analysis of the DNA-interacting proteome on a timescale of minutes. #DNA #Chromatin #Proteomics www.cell.com/cell/fulltex...

submitted 27 days ago • 2 comments

🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!

submitted 36 days ago • 34 comments

This is the way we recommend everyone make targeted proteomics assays. We've been doing it this way for 6-7 years now but only recently got around to putting a manuscript together. We use it for everything from SRM to PRM. Great work by @deannaplubell.bsky.social

submitted 38 days ago • 0 comments

Phosphorylation depends both on the sequence and on spatial proximity in vivo between kinases and their substrates. Both of these factors are accounted for in this preprint 1/2

submitted 39 days ago • 1 comment

New Paper from the Lab 🎉If you are interested in USP30, protein engineering and targeting DUBs with small molecules I can wholeheartedly recommend this Paper 😊

submitted 44 days ago • 1 comment

ibaqpy: A scalable #Python package for baseline quantification in proteomics leveraging #SDRF metadata www.sciencedirect.com/science/arti.... We continue our effort to provide tools and algorithms that leverage SDRF metadata to perform quantitative proteomics analysis.

submitted 55 days ago • 1 comment

🚨 New in @naturemethods.bsky.social #CHIMERYS has already transformed #proteomics since 2022, powering DDA, DIA & PRM analysis in a single workflow. Wanna know how CHIMERYS works? 👉 www.nature.com/articles/s41... #TeamMassSpec #NatureMethods #ASMS2025 🧪🔬 1/7

submitted 58 days ago • 3 comments

"Science of a coffee cup: A physicist walks into a bar and annoys everyone with unsolicited experiments." A good read for a cloudy Sunday. Now I can annoy my labmates with this knowledge. pubs.aip.org/aip/pof/arti...

submitted 81 days ago • 0 comments

#teammassspec does anyone use 96-well plates from Macherey-Nagel with the HR-X material? Either the 85 or 45μm format? If not, can one recommend another plate for C18 based desalting? Ideally something suitable for small amounts of peptides.

submitted 87 days ago • 3 comments

A basic solution to a very common problem. collab with @kusterlab.bsky.social and @bendavisgroup.bsky.social www.mcponline.org/article/S153...

submitted 97 days ago • 2 comments

Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n

submitted 99 days ago • 55 comments

Happy to meet at my poster P01-6 at the @DGMS in Göttingen to discuss the effect of mechanical stress signalling and different mass spec methods for analysis.

submitted 106 days ago • 0 comments

One of the most significant and challenging projects of my career so far. PepCentric: a scalable computational platform utilizing novel 2-D fragment indexing for rapid peptide-centric searches, enabling proteogenomics searches against billions of spectra in seconds. www.biorxiv.org/content/10.1...

submitted 107 days ago • 3 comments

Happy @warscheidlab.bsky.social Team after three days training on the Thermo #Astral. Many thanks to Michal Nadler Holly for such a great course! #TeamMassSpec #proteomics #PhDlife @lakshitaaa.bsky.social @johannes-uni-wue.bsky.social @hirakdas.bsky.social

submitted 124 days ago • 0 comments

@warscheidlab.bsky.social is finally also on bluesky. We are a Würzburg-based proteomics lab with research interests in peroxisomes, mitochondrial import stress or mechanical stress in skeletal muscle cells.

submitted 124 days ago • 0 comments

Job alert 🧪 ‼️ Hi #teammassspec: In our #RTG2467 @unihalle.bsky.social we have a job opening for a PhD student in my group! 🎉 If you want to do cool stuff in cross-linking mass spectrometry of the tumor suppressor p53, please take a look: personal.verwaltung.uni-halle.de/jobs/wissmi/ Please RT!

submitted 132 days ago • 2 comments

Applying LLMs to biomedical research today can go one of two ways: we either use a closed-source web app, or we get coding ourselves. Many researchers lack training for the latter, so their only choice is the former. We want to change that. www.nature.com/articles/s41...

submitted 134 days ago • 2 comments

Hello #proteomics and #science World! Short intro to myself: End of last year I finished my PhD at the @cecad.bsky.social in the KruegerLab and started now my postdoc in @jesperolsenlab.bsky.social, where I continue working on spatial proteomics! @ypic.bsky.social member with the full heart❤️

submitted 135 days ago • 1 comment

Reminder that @europepmc.org is a mirror of Pubmed with better search and that it indexes all bioRxiv preprints (as well as ResearchSquare), not just the ones funded by NIH like chauvinist Pubmed

submitted 138 days ago • 9 comments

Where do you prefer to input across samples in MS-proteomics? 1- In match-between-runs - considering MBR as some kind of imputation. 2- peptide level 3- protein level 4- All levels.

submitted 140 days ago • 3 comments

Automated High-Throughput Affinity Capture-Mass Spectrometry Platform with Data-Independent Acquisition pubs.acs.org/doi/10.... --- #proteomics #prot-paper

submitted 142 days ago • 0 comments

Can someone running XCalibur 4.5 with a Waters M-class and 96 well plates please get in contact with me? We are trying to switch to 96 well plates from 48 vial racks and are having problems. I need some guidance! #massspechelp

submitted 149 days ago • 1 comment

Who doesn't want to have an LC-MS angel on his or her shoulder from time to time!

submitted 154 days ago • 0 comments

Less than one month until I retire from full time work. I am going to offer training and consultancy from early march 2025, so if you know of anyone who would like training on LCMS systems or consultancy on proteomics sample prep etc please mention my name.

submitted 154 days ago • 1 comment

We have a feeling you'll be interested in this one. Nature is keen to find out how scientists are using Bluesky and whether it has become their go-to social-media platform. Take the survey! 🧪

submitted 155 days ago • 19 comments

Best graphical abstract of 2025 so far!

submitted 156 days ago • 1 comment

🎉 We're happy to announce that our latest project was published in @naturecomms.bsky.social this week: PTMNavigator, a #bioinformatics web platform for in-depth analysis of post-translational modification (PTM) perturbation datasets. 📄 doi.org/10.1038/s414... (1/6)

submitted 159 days ago • 1 comment

Nice shortcut to quickly check if your PTM sites are in a structural neighbourhood or interesting interaction surface

submitted 161 days ago • 0 comments

Voila! The Research Integrity Feed hashtag list for post inclusion 📊🔍👀 #ResearchIntegrity #PredatoryPublisher #PredatoryPublishing #EditorialIndependence #SciRetraction #PaperMill #PaperMills #HijackedJournal #HijackedJournals #ImageForensics #FoSci #ThisImageIsFine #DoctoredImage Cheers 🍻

submitted 164 days ago • 3 comments

Hey #TeamMassSpec, with all the super duper ultra fast TOF based DIA methods out there, how are you managing the throughput & depth on your old tribrids, QEs and Exploris? Any TMT aficionados out here getting 30spd, for instance, or even 15 with >8k proteins?

submitted 163 days ago • 3 comments

📣📣First post for many things: 1st one in bluesky and 1st one of my work since joining CNIC! Preprint for our novel implementation of PAC and DIA for REDOX proteomics, with application to cardiovascular diseases♥️🐖🔬. Check it out in @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

submitted 178 days ago • 0 comments

Post-Doc Position WANTED⚡️ I'll finish my PhD work within the next few month and started to sort out where to continue doing exciting science. Any recommendations & suggestions are welcome🙏 More information on my scientific background and ideas for the future below 🧵 reskeet very much appreciated!

submitted 179 days ago • 1 comment

Hello #ChemSky! We're excited to be part of this community, and we look forward to connecting with you here. Excuse us while we take a moment to get situated before we share more.

submitted 208 days ago • 4 comments