karihoffman.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Do everyone a favor and read this. Then act. 🧠📈🧪

submitted 6 days ago • 1 comment

#preprint: We mapped the structure and function of olfactory bulb circuits with in vivo 2-photon microscopy and synchrotron #Xray holographic nanotomography. doi.org/10.1101/2025... @yuxinzhang.bsky.social @andreas-t-schaefer.bsky.social @apacureanu.bsky.social @crick.ac.uk @esrf.fr

submitted 9 days ago • 1 comment

👀Come for the 3D microscopy porn, stay for the ensemble coding principle. I will never not like the olfactory circuit organization. Here’s a punchline post in the thread:

submitted 8 days ago • 0 comments

Stimulating vosstacular stim work, and another case of targeting lateral temporal lobe (not medial) for stim in humans. ❓🙋🏻‍♀️ to Joel/Jim: you did parietal stim before, so would you pick LTL or Par. for therapeutic target to address “MTL”ish memory impairment? Or neither? 🧠 📈 🧪

submitted 8 days ago • 1 comment

In spiking neural networks, neurons communicate - as in the brain - via short electrical pulses⚡(spikes). But how can we formally quantify the (dis)advantages of using spikes? 🤔 In our new preprint, @pc-pet.bsky.social and I introduce the concept of "Causal Pieces" to approach this question!

submitted 9 days ago • 1 comment

Nice approach to “what happens in the wake of a ripple?”

submitted 11 days ago • 1 comment

Yay, Canada! 🇨🇦🎉♥️ Elbows up and keep your science strong www.cbc.ca/news/politic...

submitted 11 days ago • 0 comments

'Exodus of the bright minds', my interview for @spiegel.de "The Trump administration is harassing science, cutting funding to universities, and intimidating researchers and students with expulsions. Four scientists share why they want to leave the country." #SpeakOut www.spiegel.de/wissenschaft...

submitted 12 days ago • 4 comments

I wrote something up for AI people who want to get into bluesky and either couldn't assemble an exciting feed or gave up doomscrolling when their Following feed switched to talking politics 24/7.

submitted 15 days ago • 18 comments

Did they really just go from freezing memories to frozen memories 🥶? @tjryan.bsky.social you need a trip to the tropics 🌴. Impressive study, broad implications for general physiology 🧪

submitted 16 days ago • 0 comments

Leaner and meaner than a transformer? B/c #BTSP? Ok correlation-based cognitive map learner (CCML), you have my attention. 🧠📈🤖

submitted 18 days ago • 0 comments

Rategory learning: antidromic systems consolidation. Not really, but it’s pithy. 🧠📈

submitted 19 days ago • 0 comments

Excited to announce the Madison Symposium on Memory and Control! postlab.psych.wisc.edu/msmc/: @paller.bsky.social, @karihoffman.bsky.social, Joel Voss, @charan-neuro.bsky.social , Thilo Womelsdorf, @earlkmiller.bsky.social . Best talk titles ever! (vote for your favorite here 🤗)

submitted 19 days ago • 2 comments

At least 28 Alzheimer's-related research projects, totaling $223.7 million, had been terminated by #NIH as of April 11. #Alzheimers #dementia #science #NeuroSky #GeriSky

submitted 22 days ago • 1 comment

Trump proposes massive NIH budget cut and reorganization www.science.org/content/arti...

submitted 21 days ago • 1 comment

Best takedown I've read on the war on science. It matters to make these points. I hope some affected editors-in-chief read this before making extremely consequential decisions next week.

submitted 22 days ago • 1 comment

🧠📈

submitted 23 days ago • 0 comments

Yup - or single-purpose/reductionist [models of] behaviors when the system must manage multiple goals IRL. If we race to the bottom with low-D tasks, should we then marvel at how scalar/categorical the response? elifesciences.org/articles/908...

submitted 22 days ago • 2 comments

Ok so yeah, this has quickly become the #1 misunderstanding about the canceled grants the grants are not “subsidies” or “entitlements” to Harvard or Princeton or whatever they aren’t going into universities’ endowments they are competitive contracts won by these universities to do research

submitted 23 days ago • 123 comments

🌎❤️‍🩹More US own-goals: undermining research by threatening int’l ties, from how we recruit the best students to procurement of specialized parts. This study was led by the gutsy, thoughtful @sabbaspoor.bsky.social using 🇬🇧 Cambridge Neurotech and 🇨🇦Brainsight/Rogue Rsh parts. In the before times.

submitted 22 days ago • 0 comments

Our new paper is out in Science. What is the synaptic plasticity rule in the brain, we asked. It turns out there are multiple, even within individual neurons. Congrats Jake! www.science.org/doi/10.1126/...

submitted 23 days ago • 2 comments

Multiple learning rules in different parts of dendrites. Definitive goodbye to hoping the brain is simple...?? 😯 www.science.org/doi/10.1126/...

submitted 22 days ago • 3 comments

Does your research involve comparing experimental conditions? Then our latest publication is for you: We developed generalized contrastive PCA (gcPCA), a tool for comparing high-dimensional datasets. 🧠📊 doi.org/10.1371/journal.pcbi.1012747 This tool was born out of necessity, here is the story. 🧵 1/

submitted 23 days ago • 4 comments

Explore top neuroscience meetings and events. Filter events by topic, and see upcoming webinars compiled by @worldwideneuro.bsky.social. Are you organizing a neuroscience conference? Share it with us at [email protected] #neuroskyence www.thetransmitter.org/events/?utm_...

submitted 23 days ago • 0 comments

I wrote a little digest + tribute to an article that shaped my career: Sadtler et al Neural constraints on learning! (and also managed to sneak in a shout out to another one) Read for free here: rdcu.be/eg5To Thanks to the editors for the invite and input!

submitted 24 days ago • 0 comments