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kirilerasov.bsky.social
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Pharmacologic and genetic inhibition of 15-PGDH protects the Blood-brain-barrier, blocks production of reactive oxygen species, prevents downstream neurodegeneration, and preserves cognition in mouse models of AD www.pnas.org/doi/10.1073/...

submitted 11 days ago • 0 comments

🧠 Protecting the brain’s gatekeeper A new study finds that blocking the enzyme 15-PGDH preserves the blood–brain barrier, halts neurodegeneration, and protects cognition in mouse models of Alzheimer’s and brain injury. 🔗 www.pnas.org/doi/10.1073/... #SciComm #Alzheimers #Neuroscience 🧪

submitted 12 days ago • 0 comments

“He remained annoyed with himself until he realized that not knowing what he wanted was actually quite natural.” Fiction by Milan Kundera, from 1984.

submitted 11 days ago • 6 comments

🦥📉 Rise and Fall of Giant Sloths Once elephant-sized and even aquatic, sloths roamed the Americas for 30 million years. New research links their sudden extinction ~15,000 years ago not to climate - but to humans. 🔗 doi.org/10.1126/scie... #SciComm #Paleontology #Sloths 🧪

submitted 11 days ago • 2 comments

Victims of a knife attack Friday night in Hamburg, Germany, were in stable condition, the local police said on Saturday as they continued to investigate the motive of the woman who they said stabbed 18 people at the city’s central train station during Friday’s rush hour.

submitted 14 days ago • 12 comments

Important discovery! Andrea Cox Lab (JHU) Sci Transl Med SARS-CoV-2 upregulates LOX-1 and PD-L1 in NEUTROPHILS—turning them into SUPPRESSIVE PMN-MDSCs IMPLICATION: targeting PD-L1 with immune checkpoint inhibitors may restore T cell responses and reduce severity www.science.org/doi/10.1126/...

submitted 16 days ago • 3 comments