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levayerr.bsky.social
Epithelial cell death, cell extrusion, self-organisation, mechanotransduction and many other things
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Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did! www.philanthropy.cam.ac.uk/give-to-camb...

A new #ScienceSignaling study interrogates crosstalk between mechanical and biochemical signals in epithelial cells, illustrating how mechanical stretching activates a kinase that regulates cell growth, migration, and differentiation.

What is buckling, and why is it relevant in understanding epithelial morphogenesis? 🧐 I am @onenimesa.bsky.social and I will share some papers to understand this aspect of #EpithelialMechanics

πŸ”₯ We've already received over a third of pre-registrations! ο»Ώ#Mifobio2025 is already shaping up to be a highly attractive event... Don't delay in pre-registering! πŸ‘‰ imabio-cnrs.fr @cnrs.fr @cnrsbiologie.bsky.social @cnrsingenierie.bsky.social @cnrs-inist.bsky.social

πŸ“£Next @devstempasteur.bsky.social Seminar this Friday : Fiona Doetsch from the Biozentrum University of Basel will speak about : Adult Neural Stem Cells: Regulation & Heterogeneity Invited by Shahragim Tajbakhsh

Second preprint from the lab in a week! This time led by Aurelien. Combining live imaging, quantitative image analysis and perturbations, he clarifies the mechanisms leading to primitive induction. πŸ‘‡

Super excited to share that the final version of our study on the role of Adenylate Kinase 7 (AK7) on centriole maturation is finally out! @devbiol.bsky.social Read the full version here: www.sciencedirect.com/science/arti...

Many cells during development are exposed to caspase activation and yet survive. Why some die and not others ? We found out that the memory of previous caspase activation bias significantly later death comitment and bias death distribution and single cell decision www.biorxiv.org/content/10.1...

πŸš¨πŸ“£ New preprint alert! Excited to share my new postdoc work on direct force and mechanical properties measurements in live embryos! A great team effort with A. Chamolly (theory), under the supervision of F. Corson and @jeromegros.bsky.social πŸ“„ www.biorxiv.org/content/10.1... #devbio #mechanics

Just one week to go ⏳ until the "Cellular Interfaces Across Scales: From Molecules to Tissue Dynamics" meeting @sfb1348.bsky.social @uni-muenster.de We can't wait to see you there! crc1348-conference.ycode.site #DynamicCellularInterfaces #Münster

This issue has become more acute in recent years. A narrow view of "mechanistic" experiments holds us back. "A case for broadening our view of mechanism in developmental biology" journals.biologists.com/dev/article/...

🚨 The application deadline for the #EMBODrosophila practical course is fast approaching 🚨 ⏰ Apply by 4 May and join us for a week of immersive learning with lectures from world-renowned experts and hands-on practical sessions πŸ‘‰ https://s.embl.org/drg25-01-bl πŸ—“οΈ 3 – 8 August πŸ“ EMBL Heidelberg

The Gulbenkian Institute of Molecular Medicine (GIMM) is one of the best research institutes in Portugal. It's currently recruiting for three Group Leaders (junior or senior) across different areas, including systems biology and bioinformatics. gimm.pt/jobs/open-ca...

Stoked to present our latest, superbly led by Chris et al & @torres-sanchez.bsky.social We tackled a fundamental problem – how tissues are patterned during development – found that geometry-constrained ECM fractures pattern the myocardium in the vertebrate heart 1/n www.biorxiv.org/content/10.1...

In their Cell Science at a Glance article, @alinegrata.bsky.social & @levayerr.bsky.social @pasteur.fr describe the remodelling steps that take place within dying or extruding cells, outlining the commonalities & variations between tissues &organisms. journals.biologists.com/jcs/article/...

Calling all fly researchers! Submit your abstracts before 28 May! Looking forward to seeing all the great #drosophila research going on at #EDRC2025 in Spain @edrc2025.bsky.social @fly-jedi.bsky.social @fly-eds.bsky.social

Interested in Developmental Mechanics??? We are organizing a mechanobiology workshop in Baeza, Spain, October 21-23, 2025. Come join us (and please help us spread the word)!!!

Cell and developmental biologists: as you start looking at conferences in 2025, consider joining us at the 2025 Cell Contact & Adhesion GRC. We've assembled a strong and diverse program of speakers at the cutting-edge of science in our field 1/n Please repost www.grc.org/cell-contact...

In developing embryos, cells move a lot! Plenty of that movement is random. Is random cell mixing a feature or bug for tissue patterning? Turns out, it’s both! Excited to share the 1st preprint from my postdoc w/ Sean Megason @seanemcgeary.bsky.social and Allon Klein. 1/20 doi.org/10.1101/2025...

Everything you always wanted to know about cell extrusion in one poster...check out this nice visual piece from @alinegrata.bsky.social and the accompanying review in this "at a glance" piece of @jcellsci.bsky.social journals.biologists.com/jcs/article/...

In our latest interview, we hear from the 2024 @bscb-official.bsky.social Hooke Medal winner Emmanuel Derivery @deriverylab.bsky.social. Emmanuel tells us about his research, what winning the Hooke Medal means to him & his advice on building a successful lab. journals.biologists.com/jcs/article/...

If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social

REPOSTING this here just to officially leave "the other place" Our work on the role of endogenous electric fields in guiding collective cell migration during #morphogenesis is out @naturematerials.bsky.social nature.com/articles/s41...

New article of the lab on Notch3, not only involved in vascular or neural defects, but also in heart defects and laterality defects.

How is extrusion of infected host cells related to ERK (extracellular signal-regulated kinase) activity? Hi, I’m @hundsdorfer.bsky.social from the @effiebastounis.bsky.social lab. Let’s follow the recent development of bacterially-infected cell extrusion & mechanochemical ERK activity waves.

🧬 New article from the SGR "REGnetREG" @geneticsub.bsky.social @biologiaub.bsky.social about "Cell Death in Regeneration and Cell Turnover: Lessons from Planarians and Drosophila". πŸ“„ Enjoy 50 days of free access to the article at this link: πŸ‘‡πŸ‘‡πŸ‘‡πŸ‘‡πŸ‘‡πŸ‘‡πŸ‘‡ www.sciencedirect.com/science/arti... 1/2

Happy to share our new publication in @naturematerials.bsky.social on mechanical cell competition! Great collaboration between our CAM team, Chavrier's and Doostmohammadi's. Special congrats @luanger.bsky.social, @andreasschoenit.bsky.social, Siavash Monfared! πŸŽ‰ www.nature.com/articles/s41...

What happens between cells with adhesion differences in crowded tissues? Mechanical cell competition! Check the final version of our study to learn more about compression-independent cell elimination, interactions at tissue interfaces and the role of force transmission in that tinyurl.com/4yw97bm3