marcveld.bsky.social
Professor of Immunology 🇳🇱 🇬🇧
Lisbon, 🇵🇹
#Immunology
Time for Science, not silence
https://scholar.google.co.uk/citations?user=7vG1jLIAAAAJ&hl=en
https://orcid.org/0000-0002-1478-9562
threads.net/@marc_veld
mastodon.online/@marc_veld
14,447 posts
10,842 followers
1,263 following
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When you claim the earth is flat and you are presented pictures of the curvature, the calculations it is spherical, the experimental data you can measure it and see the curvature, you can nolonger question it: it is spherical.
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When it rains and you question that: you will be told to go outside. Once outside you observe the rain and you get wet. You can nolonger question if it is raining.
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can be reduced or switched off if not essential. Like agains bacteria and viruses, there is a selction of those tumour cells with the best fit, such as those escaping (really escaping) immune detection by not expressing neo-antigens.
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One of the difficulties is identifying tumour-specific antigens. This is possible with sequencing techniques. The next problem remains tumour escape. Tumour is self, and your immune system is not suposed to recognise self, only non-self. This leaves few if any tumour- antigens that
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potential drug target.
The paper also shows the importance of type I IFNs in containing SARS-CioV-2. Reduced activity of nsp15 reduces the innate response and hence, the production of IFNs, allowing more virus to be generated and to spread.
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NOT mean it escapes detection. It is the constant evolution between pathogen and host,
SARS-CoV-2 variants lacking nsp15 activity elicited higher innate immunem exhibit impaired replication and cause milder disease in animals, highlighting nsp15 as a key virulent factor, and
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This study focusses on the SARS-CoV-2 nonstructural protein 15 (nsp15) and demonstrates that its endoribonuclease activity delays the activation of antiviral responses in human lung cells. Note delay. The virus tries to allow sufficient time to infect and transmit. This does
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Have you tried IVM?
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I think it is a "worst case" or what "could happen". It is not at that stage yet.
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Especially if it does not have a graphics card, you are pretty much blind!
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The VA has since ceased providing most gender-affirming care and forbidden a long list of words, including “gender affirming” and “transgender”, from clinical settings.
Freedom!
It is going back to the middle ages becaus of ideologicy.
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Doctors and other medical staff can also be barred from working at VA hospitals based on their marital status, political party affiliation or union activity, documents reviewed by the Guardian show.
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"individual workers are now free to decline to care for patients based on personal characteristics not explicitly prohibited by federal law."
A logical next step derived from MAGA and MAHA ideology.
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—the conspiracy theories didn’t stop. Instead, they just changed.
“When someone on the far-right commits a violent act, [right-wing conspiracy theorists] have to deflect the blame elsewhere,"
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When the facts of the story emerged—that the alleged shooter had been registered in other states as a Republican, was said to have voted for President Trump and, as WIRED reported, had participated in an evangelical ministry where he preached against abortion and demonized the LGTBQ community
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In the hours after Vance Boelter was named as the suspect in the fatal shooting of Melissa Hortman, a Democratic Minnesota state representative, and her husband Mark Hortman, far-right conspiracists and Republican influencers claimed he was a violent, leftist Democrat.
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finds that, on average, the new panel members have been authors on about 78% fewer vaccine-related papers than the ousted members. Four of the eight new members have published no such papers at all.
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finds that, on average, the new panel members have been authors on about 78% fewer vaccine-related papers than the ousted members. Four of the eight new members have published no such papers at all.
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Several of the new members of the Advisory Committee on Immunization Practices (ACIP) have clearly expressed antivaccine sentiments in the past and appear to have little experience with vaccine science at all. Indeed, a Science analysis of their publications in peer-reviewed biomedical journals
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Several of the new members of the Advisory Committee on Immunization Practices (ACIP) have clearly expressed antivaccine sentiments in the past and appear to have little experience with vaccine science at all. Indeed, a Science analysis of their publications in peer-reviewed biomedical journals
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Unless both sides acknowledge and respect each other’s trauma and suffering, the cycle continues. More pain, more rage, more death. Understanding and mutual acknowledgement are not weaknesses; it’s the only route out of endless war.
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now and for the future, to avoid even a small potential chance that another Holocaust could ever happen again. It is not an excuse; it is embedded in the national psyche, it is real.
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The Arab people acknowledge and understand that Israel will respond, directly and violently, because they feel threatened. There is a long history of persecution, of expelling the Jewish people, the Holocaust, and the threat to their existence. They will do everything to defend themselves,
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The people of Israel are coming to terms with and understanding the suffering of the Arab people. To see what their military is (commanded) to do in Gaza, to understand that new settlements and discrimination are a huge threat to the Arab people and thus peace.
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Israeli society must face what its government and army are doing in Gaza. The Arab world must understand the existential fear rooted in Jewish history. Without mutual recognition, nothing will change.
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The blame lies squarely with the Hamas and Israeli (and Iranian) leadership. They sustain war, deny responsibility, and block empathy. Neither side moves toward peace, only toward more devastation. Both harm their people, with Hamas violently crushing decent.
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If this trend of violence continues unchecked, Israel risks global isolation. It must return to the rule of law, accountability, and humanity. Likely under new leadership, after free elections. There is no other path, only more destruction and suffering if not.
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However, awareness is rising, and criticism has been present from the start. More Israelis see how their military is used: breaking laws, displacing civilians, and committing acts that cross moral and legal lines. Criticism has been growing, and it is very necessary.