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mikelz.bsky.social
I’m the Hattori Hanzo of tortilla de patata (potato omelette). Transposons, heterochromatin and, more recently, mitochondria.
8 posts 70 followers 519 following
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Posts 19 Comments 3

Every science story should begin with “ One day, someone got some funding to …”

submitted 15 hours ago • 0 comments

www.nature.com/articles/d41...

submitted 6 days ago • 0 comments

Our latest work: how can compartmentalization emerge in a eukaryotic genome lacking canonical heterochromatin? By investigating bacterial genomes put in yeast, we show that the presence or absence of transcription is sufficient! #chromatin #3Dgenome #generegulation www.science.org/doi/10.1126/... 👇

submitted 24 days ago • 3 comments

In a great collaboration with @hummerlab.bsky.social and the Kräusslich lab: HIV capsid doesn't break at the NPC; instead, it cracks open the NPC itself! Details in Cell: authors.elsevier.com/sd/article/S... @mpibp.bsky.social @uniheidelberg.bsky.social A thread below:

submitted 45 days ago • 7 comments

Lots of cool AI in Nature this week, including VLM for precision oncology www.nature.com/articles/s41...

submitted 53 days ago • 0 comments

Work led by graduate student @trinitycookis.bsky.social and coauthors Alexandria Lydecker, @paulsauer.bsky.social, and @kasinath-lab.bsky.social is out today where we looked at the inhibition of PRC2 by histone PTMs associated with regions of active transcription. www.nature.com/articles/s41...

submitted 55 days ago • 2 comments

Centrophilic retrotransposon integration via CENH3 chromatin in Arabidopsis www.nature.com/articles/s41...

submitted 60 days ago • 0 comments

Retrotransposon expression is unregulated by aging and suppressed during regeneration of the limb in the axoloti #Retrotransposon #aging #regeneration #longevity www.biorxiv.org/content/10.1...

submitted 66 days ago • 1 comment

ATP synthesis of Enterococcus hirae V-ATPase driven by sodium motive force https://www.biorxiv.org/content/10.1101/2024.12.26.630461v1

submitted 66 days ago • 0 comments

We often speak about chromatin as being accessible or inaccessible, but what does it mean? We wrote a short review on this, 🔬 focused: sciencedirect.com/science/arti... A big thank you to Tom Fillot for his efforts on this and to @hansen_lab @marcelonollmann for their help as editors.

submitted 73 days ago • 4 comments

I am very excited to share my latest work characterizing cytosine methylation of polymorphic insertions in the human population! #genomics A thread: 1/

submitted 98 days ago • 2 comments

They should have called this package “BeneGesseRit”

submitted 90 days ago • 0 comments

working on this unix redirects diagram today

submitted 102 days ago • 26 comments

Interesting findings about one of my favorite Transposons called ÉVADÉ: PTGS is dispensable for the initiation of epigenetic silencing of an active transposon in Arabidopsis. www.embopress.org/doi/full/10....

submitted 106 days ago • 0 comments

Centromeres never cease to amaze me. They have so much to tell us about evolution.

submitted 106 days ago • 0 comments

EpiSci - www.cell.com/molecular-ce...

submitted 106 days ago • 0 comments

It’s unbelievable that even today, in the year of our lord 2024, we are still discovering absolutely fundamental stuff about mitochondria www.cell.com/cell/fulltex...

submitted 107 days ago • 0 comments

The Salk Institute shared the sad news that Prof. Joanne Chory passed away yesterday due to complications from Parkinson’s disease. She was one of the most influential biologists of our time. And this is how I will remember Joanne, expertly guiding us on where to go. Joanne, we will miss you! ❤️

submitted 110 days ago • 11 comments

The year is 2024, a future you’ll probably live to see

submitted 111 days ago • 0 comments