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mito-at-gu.bsky.social
The Human Mitochondrial DNA Replication and Gene Expression Team at the University of Gothenburg http://falkenberglab.org http://gustafssonlab.org
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Prolific Poster

The brain’s energy landscape as a potential window into brain health www.nature.com/articles/d41... (study led by Martin Picard and Michel Thiebaut de Schotten)

🚨 #Postdoc Opportunity! 🚨 The @vkohler-lab.bsky.social @umeauniversitet.bsky.social is hiring! Join a dynamic team tackling #proteostasis in #ageing, with outstanding mentorship from @verenakohler.bsky.social - a PI deeply committed to your career development and scientific growth. Apply now!

🚨 Join us for the @faseborg.bsky.social Meeting on Mechanisms of Mitochondrial DNA Mutation and Repair, June 1 - 5, 2025 | Nashville, Tennessee. 📅 Abstract submission & Early Registration close on April 20, 2025! Don't miss out: events.faseb.org/event/mitoch... Please re-post!

Swiss Federal Institute of Technology Lausanne (CH): Postdoctoral Position in Human Metabolism, Mitochondria & Behavior (1509) leibniz-psychology.org/produkte/job... #Stellenangebot

Nature reports on how researchers are studying why mitochondria are moving between cells and whether the process can be harnessed to treat cancer and other diseases. 🧪

New research from our lab on mitochondrial DNA stability RRM2B is essential for making dNTPs in non-dividing cells and its loss causes mt DNA depletion syndromes. Surprisingly, we found that RRM2B deficiency leads to a drop in dATP and dGTP. www.pnas.org/doi/10.1073/...

New paper out from the Falkenberg and Gustafsson labs. Thanks to Pretzel for a successful collaboration. www.nature.com/articles/s41...

👋Our March issue's out! Cover: Introducing #blebbisomes 👉🏼Review on #mitochondria #genetics 👉🏼Perspective on #MachineLearning and #SingleCell analyses 🔬 #organelles #autophagy #cancer #autophagy #endocytosis #EmbryoPatterning & more! www.nature.com/ncb/volumes/...

Cryptic mtDNA mutations emerge mid-late life, revealing insights across species. In 1M+ cells, they map mitochondrial dysfunction to aging! #AgeingResearch PMID:40050638, Nat Commun 2025, @NatureComms https://doi.org/10.1038/s41467-025-57286-8 #Medsky #Pharmsky #RNAsky 🧪

Excited to share my first postdoc paper - a tool to engineer mtDNA deletions in human cells and study their pathogenic impact ✂️🧬🧫

Join me and Patrick Chinnery, Luca Scorrano, Aleksandra Trifunovic, and Min Jiang for the Westlake - @science.org Online Symposium Wed 28 March 13.00 CET/20.00 China Mitochondria in health and disease us02web.zoom.us/webinar/regi...

mtDNA goes places, and sometimes nucleoids end up in stressful situations. Our next speaker @lauraenewmanphd.bsky.social is keeping an eye (or two) on this, and will tell us all about it. This week, usual time and place.

Ready to make breakthroughs in gene editing and mitochondrial biology in sunny Western Australia? Join our vibrant team as a Research Associate or Research Fellow. Expertise in cryo-EM, cell imaging, or mammalian genetic screens is highly desirable staff.curtin.edu.au/explore-care...

Our newest paper on mtDNA instability signaling by Gustavo Carvalho, Tran Nguyen and Bruno Repolês et al is out: Activating AMPK improves pathological phenotypes due to mtDNA depletion - Carvalho - The FEBS Journal - Wiley Online Library febs.onlinelibrary.wiley.com/doi/full/10....

Cancer cells can poison attacking immune cells by filling them with defective mitochondria ― dampening the body’s defensive forces and helping the tumour to evade eradication https://go.nature.com/42qye6G

💫Amazing view of mitochondria It would be fascinating to see this in people with #pese #longcovid #ME

Hi all, our lab will soon recruit a PhD student working within a very exciting MSCA Horizon Doctoral network working on ageing, UNION, which gathers some fantastic scientists. Please apply if your profile fits our project (see attached advert). Looking forward to working with you!

New structural and functional analyses show that FASTKD4 supports non-canonical RNA processing and MT-ND3 mRNA stability. Thanks to all authors for their contributions and the reviewers for their kind advice! academic.oup.com/nar/article/... #RNA #mitochondria #mtDNA

For those starting on BSKY and loving #metabolism and #mitochondria, the 2 starter packs have now been completed. 300 scientists working in this field are here to be followed! Happy Boxing Day Starter pack 1: go.bsky.app/VavECSX Starter pack 2: go.bsky.app/CH1MctZ

The link between mitochondrial bioenergetics and brain aging reported in Science. A beautiful study by our neighbours, Huan Ma lab demonstrates that restoring excitation-transcription coupling in mitochondria can improve memory function. This has a potential to reverse age-related cognitive decline.

Boosting neuronal activity-driven mitochondrial DNA transcription improves cognition in aged mice www.science.org/doi/10.1126/...

Happy to share our new story on the role of TFAM in regulating mitochondrial DNA repair and lesion accumulation. academic.oup.com/nar/advance-...

What are your plans for October 2025? It would be a fantastic time to visit Norway for the Endogenous DNA Damage and Repair conference with a stellar set of speaker covering a wide range of topics. www.endodnadamage.com

Stunning image from @claudiobussi.bsky.social 🤯

Warm welcome to Christof Osman 'Studying the mysteries that surround the genome of the cell's powerhouse'. To stay updated on the latest in mitochondrial genome field, follow @osman-lab.bsky.social

Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice

Our opinion piece is out! My first published postdoc work with Lena Pernas. 🎉 Here, we speculate whether mitochondria can autonomously sense and elicit a response to microbes. 🤔🦠 #mitochondria #microbes dlvr.it/TGLcRm

I just created a starter pack to collect accounts related to mtDNA research. Feel free to contact me if I should put someone on the list go.bsky.app/BiCguQz

🔬 Curious about #mitochondria #imaging but unsure where to begin? Our review might help! 🚀📜🧪 www.annualreviews.org/content/jour... #Quantitative #Microscopy #SuperResolution #AcademicSky #ScienceSky #CellBiology #mtDNA

Who are some amazing cryoEM/cryoET, mass spec, and light microscopy scientists coming to San Diego for ASCB? I’m making a list for a potential pre-ASCB workshop at UCSD December 13th. Spread the word and let me know if you know a good candidate to speak at such an event!

Hi everyone! 👋 We’re the Max Planck Institute for Biology of Ageing, and we’re passionate about studying the biology of ageing to help promote healthier ageing in humans. We’d love for you to follow us to keep up with our latest discoveries, insights, and events! 🧬🔬🧓🧑‍🔬 www.age.mpg.de/research

Systems and synthetic biologists, we are recruiting at the department of Systems Biology at the @UMassChan. Position is open to faculty at all levels. http://academicjobsonline.org/ajo/jobs/25423

From our lab: The POLγ Y951N Mutation, disrupts the Key Switch Between DNA Synthesis and Proofreading, Triggering Mitochondrial DNA www.biorxiv.org/content/10.1...