mkeller7.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

HUGE: Senate Parliamentarian says that Mike Lee's public land sell-off violates the Byrd rule, requires 60 votes in the Senate. A bunch of other terrible anti-environment provisions do too. This isn't over, but this is a huge win. www.budget.senate.gov/ranking-memb...

submitted 11 hours ago • 114 comments

SCOTUS majority not deigning to give any reasons for staying the injunction of the district court - in the highest-possible stakes context & where the executive branch has acted appallingly - evincing real contempt for both district courts & the rule of law

submitted 1 day ago • 162 comments

Explore Wikipedia through a data map. Pages are grouped by semantic similarity, for topic clusters. Hover to see details, zoom to explore more fine-grained topics, click to go to a page. Search by page name to find interesting starting points for exploration. lmcinnes.github.io/datamapplot_...

submitted 2 days ago • 6 comments

If this bill passes, our public lands will fall into the hands of fossil fuel interests.

submitted 6 days ago • 238 comments

i've been trying to see what the right wing platforms (even outside of X) are showing people regarding the protests in LA and i am not sure it can be overstated just how much the AI slop is being used to reinforce the idea that downtown is a post-apocalyptic war zone

submitted 13 days ago • 247 comments

BREAKING: A few minutes ago, a vehicle of three people was rammed by a truck belonging to federal immigration authorities in Boyle Heights, CA. According to security footage shown to me, they deployed chemical munitions & detained the driver at gunpoint. All are US citizens according to the wife.

submitted 13 days ago • 2310 comments

This is a superb speech by @governor.ca.gov just now. Clear. Strong. Simple. Direct. Angry—in a way that appeals to the best in people, not the worst. Seven plus minutes of the most effective rhetoric in response to Trump. This is how you want a leader to talk. www.youtube.com/watch?v=linJ...

submitted 13 days ago • 92 comments

What a special atmosphere! #ELMI2025 Poster Session 1 on Helix A last night. The perfect environment to exchange with friends & colleagues about #bioimaging #RDM: - OMERO-vitessce - IO-FAST initiative - @nfdi4bioimage.bsky.social Data Stewardship Talks, Workshops & Poster Session 2 up ahead today!🔬

submitted 19 days ago • 0 comments

Analyzing your single-cell data by mapping to a reference atlas? Then how do you know the mapping actually worked, and you’re not analyzing mapping-induced artifacts? We developed mapQC, a mapping evaluation tool www.biorxiv.org/content/10.1... from the ‪@fabiantheis lab. Let’s dive in🧵

submitted 21 days ago • 2 comments

"Our calculations suggest that the proposed budgetary cuts to the NIH will create a social cost that is 16 times greater than the savings that the administration is attempting to achieve." jamanetwork.com/journals/jam...

submitted 25 days ago • 11 comments

Agreed, this is something missing from current discourse, how bad AI is at abstractions/architecture/composition/interfaces. Perhaps it can be addressed but it also seems uniquely difficult

submitted 25 days ago • 0 comments

Everyone should watch and share. Thank you David. youtu.be/8YhJM6zxYDw

submitted 29 days ago • 2 comments

5 years ago: “An incalculable loss” Today: Banning masks and restricting vaccine access

submitted 30 days ago • 264 comments

I appreciate the offers from other scientists to help Harvard (students, labs, etc) through this attack, but what would be most helpful is for you to use your position to contact your elected representatives and make it clear this fight isn't just Harvard, it will affect you, and their districts too

submitted 31 days ago • 9 comments

A good time to throw up obstacles to getting people vaccinated.

submitted 32 days ago • 1 comment

How does tumour heterogeneity arise? How can we predict cancer cell plasticity? In 2 new studies, we trace #glioblastoma heterogeneity to a spatial cancer cell trajectory w. multimodal cell atlassing bit.ly/4mkrWgs & predict plasticity w. snRNA/ATAC+deep learning bit.ly/3FbI6Ic 🧵

submitted 39 days ago • 6 comments

This is so amazing. It is the culmination of decades of work. It's hard to stop thinking about the lifesaving treatments that will be lost because of the damage Trump and Musk are doing to scientific research. The Republicans are burning our seed corn.

submitted 40 days ago • 1 comment

Today in @nature.com , we report a spatial single-cell atlas of human cortical development, revealing surprisingly early specification of human cortical layers and areas. We built an interactive browser to explore the spatial data: walshlab.org/research/cor... Paper link below 👇

submitted 41 days ago • 5 comments

Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab

submitted 41 days ago • 146 comments

1/ 💡 Our latest blog post in the fundamentals series, written by @tegnicholas.bsky.social, demystifies cloud-optimized scientific data formats! Read more: earthmover.io/blog/fundame...

submitted 68 days ago • 2 comments

In their haste to comply with apparent directives from Trump, universities became unwitting handmaidens of the deportation machine. interc.pt/4jCR9AD

submitted 68 days ago • 2 comments

Eloquent and timely

submitted 68 days ago • 0 comments

born too late to get a two Western blot Nature paper, born too early to be a science TikTokker, born just in time to start a postdoc during a global pandemic and look for faculty positions during a historic hiring freeze

submitted 106 days ago • 16 comments

1/ Ever wondered how to best quantify cell-cell neighbor preferences in tissues? We compared 9+ neighbor preference (NEP) methods for analysing spatial omics data and propose a novel approach that combines the most relevant analysis features which we call COZI 🔬✨ Read more: doi.org/10.1101/2025...

submitted 70 days ago • 1 comment

Hey, go look at Harvard's homepage

submitted 71 days ago • 9 comments

Some personal news: I’ve temporarily paused the tiny iPhone screw factory I was building in Ohio.

submitted 72 days ago • 78 comments

The transformer was invented in Google. RLHF was not invented in industry labs, but came to prominence in OpenAI and DeepMind. I took 5 of the most influential papers (black dots) and visualized their references. Blue dots are papers that acknowledge federal funding (DARPA, NSF).

submitted 73 days ago • 2 comments

AI2's paper finder is one of the best improvements to my research workflow in years highly recommended:

submitted 80 days ago • 0 comments

Historians Politely Remind Nation To Check What's Happened In Past Before Making Any Big Decisions theonion.com/historians-p...

submitted 126 days ago • 154 comments

It is easy to create a Bluesky feed that filters posts to those with positive (or at least non-negative) sentiment using @graze.social

submitted 128 days ago • 1 comment

I mis-added earlier, here's corrected post: How many scientists and interior workers were fired today? Between news article estimates and social posts, I count over 10k: 5200 @ NIH 1200-2000 @ DOE 800 @ USDA 2,300 @ Dept. of Interior 1,300 @ CDC (I haven't heard any FDA, EPA, or NASA numbers)

submitted 130 days ago • 10 comments

President Donald Trump’s administration today moved to fire 5200 workers at the Department of Health and Human Services, using supervisors across the vast agency to warn probationary employees that they would soon receive termination notices. scim.ag/4jYmcYA

submitted 130 days ago • 6 comments

Dreadful. Fully Preventable. More of this to come www.washingtonpost.com/health/2025/...

submitted 131 days ago • 28 comments

Can we learn protein biology from a language model? In new work led by @liambai.bsky.social and me, we explore how sparse autoencoders can help us understand biology—going from mechanistic interpretability to mechanistic biology.

submitted 134 days ago • 2 comments

Whenever you hear someone sneer about scientific research that seems useless to them — “they’re studying the spit of lizards?!” — remind them that’s exactly how we got Ozempic. globalnews.ca/news/9793403...

submitted 135 days ago • 524 comments

Government isn't a business. The goal isn't to save money. Success isn't measured by budget surplus. The goal is to spend money, investing in society. Every dollar spent on education, healthcare, and science is an investment in our collective wellbeing.

submitted 136 days ago • 2 comments

The NOAA CO2 data website has vanished. gml.noaa.gov/ccgg/trends/

submitted 139 days ago • 24 comments

Really enjoyed writing this Insight on molecular phenotyping and clinical proteomics with @oligopain.bsky.social and Andy Hoofnagle. The hardest part was definitely keeping it to 10 citations with all of the exciting work in MS and non-MS proteomics applications in clinical settings!

submitted 144 days ago • 0 comments