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mkoehn.bsky.social
Prof. at University of Bonn, Chemical Biology, Phosphatases, Associate Editor at Chem. Sci., views are my own, she/her
27 posts 1,439 followers 410 following
Prolific Poster

Nominations for the Chemical Science Lectureship are closing on the 1st of March! We are looking for researchers in the area of imaging, biosensing or diagnostics, that have published in Chemical Science in the past 5 years. Find out more at rsc.li/chemsci-lect... #ChemSky šŸ§Ŗ

Did you recently complete a ChemBio/MedChem PhD (non-UK) and are looking for the next challenge? I am seeking a prospective applicant for a Newton Fellowship with an exciting project in targeted protein dephosphorylation! Please reach out to [email protected] royalsociety.org/grants/newto...

Do you love software engineering for exciting biological applications, open science, open source, R, Bioconductor, modern web, cloud & ML technologies? We're looking for a software engineer to work on R/Bioconductor tools for biological data science and AI. www.huber.embl.de/group/posts/...

#Chembio crowd! Come and join #ESBOC25, the oldest Chemical Biology Symposium in Europe, in its 58th (!) instalment, on 28th-30th May 2025 - in beautiful and scenic Gregynog/Wales! Chaired by none other than Olalla Vazquez and with a rockstar lineup: www.esboc.org.uk

Am 10. Februar 2025 startet die Abstimmung Ć¼ber die NamensƤnderung unseres Vereins in ā€žDeutsche Gesellschaft fĆ¼r Chemieā€œ. Der Vorstand der GDCh bittet alle Mitglieder um ihre Zustimmung zu diesem wichtigen Schritt. Mehr Informationen: www.linkedin.com/posts/gdch-d...

If you are member of @gdch.bsky.social, you should have gotten an e-mail that you can vote on the change of the name of GDCh to "Deutsche Gesellschaft fĆ¼r Chemie". If you have, I encourage you to make use of your vote!

Iā€™ve unfortunately needed to add more material to my post from yesterday. The re-election of Donald Trump is looking like the biggest act of American self-destruction since the Civil War. Same link, new title and some updates.

Open for nominations: Chemical Science lectureship to recognize independent researchers at all career stages who made exceptional discoveries and innovations in their field within the last five years. Focus is this time on the chemistry of imaging, biosensing and diagnostics. rsc.li/chemsci-lect...

Between 2019 and 2023, researchers paid $8.968 billion to make papers open access. Imagine what else could be done with this money if it wasnt paid to for profit publishing companies... šŸ‘‰ arxiv.org/abs/2407.16551

I had an amazing time at the #AdvancesChemBio with many interesting talks, exciting posters and inspiring discussions with colleagues and friends. Thank you so much to the organizers from @gfg-chembio.bsky.social for organizing such an outstanding meeting. #chemsky #ChemBio

Happy to share our work published www.nature.com/articles/s41.... We describe the design of activity-based probes and chemoproteomic strategies to study USP18.

Our lab is recruiting Postdocs with strong background in Epigenetics, PTM biology and/or Cell Signalling along with experience with bioinformatics šŸ‘©ā€šŸ’»šŸ‘Øā€šŸ’» šŸ“¢ Apply through the IBFG Postdoc Call 2025! šŸ”— Check all the positions here šŸ‘‡ drive.google.com/file/d/1JxNd...

If youā€™re thinking of what meeting to go to this year then check out the #phosphatase meeting in WĆ¼rzburg. Lots of great speaking slots and events for junior researchers. Itā€™s always a fun meeting meetings.embo.org/event/25-pho...

Here we are, happy to join the community!

Super excited to finally share PANCS-Binders: our group's decade-long quest to accelerate protein binder discovery. TLDR: PANCS-binders is fast (2 days), cheap (pennies), has extremely high fidelity (low false positive and negatives), and high-throughput. 1/n

For all those providing reviews of scientific papersā€“firstly, thank you. We would not have a useful scientific literature without you. Secondly, please keep in mind that your reviews are read not only by the PIs but also students. There is no place for anger or impolite language in a review.... 1/

Thrilled to share our @sciimmunology.bsky.social paper! We report that rodent PD-1 is weaker than human PD-1 (reduced ligand binding & signaling) & lacks a conserved vertebrate motif. Humanizing mouse PD-1 disrupts T cell anti-tumor responses, raising many questions. science.org/doi/10.1126/...

We are hiring! Apply to join our dynamic team as a #chemicalbiology postdoc or research scientist below. Chemical biology: jobrxiv.org/job/universi... Mass spectrometry: jobrxiv.org/job/universi...

Join us in WĆ¼rzburg, Germany, for the EMBO workshop ā€œPhosphatases: From basic research to translationā€! July 27-31 2025. Newest developments in the field, from academia and industry. Great networking opportunities! Short talk slots available. Hope to see you there! meetings.embo.org/event/25-pho...

Scientists to Follow! As my "Scientists to Follow" list (go.bsky.app/3SyoVNw) reached capacity and I did not want to extend the short list (go.bsky.app/C4URhFa), I made a part 2 with plenty more scientists that post exciting content here: go.bsky.app/9keb2TP Please share this post! (1/n)

Who is messing with your favorite protein Filamin C in stressed muscle cells? šŸ§©šŸ”¬ We tackled this riddle in our latest paper in Scientific Reports. A huge shoutout to former lab mate Anja and Thomas from the @mkoehn.bsky.social lab - this was a true team effort! šŸ‘šŸŽ‰! A short thread: šŸ§µ(1/5)

Big thanks to Johannes, Thomas Kokot, Bettina Warscheid and everyone involved in this wonderful collaboration!

Join us in WĆ¼rzburg, Germany, for the EMBO workshop ā€œPhosphatases: From basic research to translationā€! July 27-31 2025. Newest developments in the field, from academia and industry. Great networking opportunities! Short talk slots available. Hope to see you there! meetings.embo.org/event/25-pho...

Really excited to see this work out! In collaboration with Prof. Jen Prescher, we showed that their cyclopropenone labeling strategy can be applied to structured RNA! Thrilled to work with this fantastic team of scientists. pubs.acs.org/doi/10.1021/...

šŸ§Ŗ #SciSky Organising a meeting? Together with EMBO, we provide funding for workshops, practical and lecture courses in Brazil, Canada, China, Japan, Mexico and South Korea. šŸ“… The next application deadline is 1 March. To find out more, visit https://bit.ly/41hbB47. #EMBO

Alguien tenĆ­a que arriesgarse a quedar mal haciendo esta lista šŸ˜Š Como estoy seguro de que me olvido de amig@s y personas que deberĆ­an estar aquĆ­, hacĆ©dmelo saber en los replies para aƱadiros. #ChemSky go.bsky.app/5WU81dp

go.bsky.app/HqEcaCw

Job alert: fully funded postdoc position in chemical biology in beautiful Geneva! Do you have a PhD in Chemical Biology or related field with organic synthetic experience? Apply now! Details on how to apply can be found here: www.hoogendoornlab.org/joinus #chemsky #ChemBio

Reminder that if disordered proteins are your thing, this starter pack exists (and I try to update it as best I can as new folks reach out/I see them!) šŸ go.bsky.app/J23B51L

cen.acs.org/pharmaceutic... AI-macrocycle design program licensed by Vilya builds on RoseTTAFold 2 and RFdiffusion

#ChemSky šŸ§Ŗ What would you like to see in terms of RSC presence on Bluesky? Do you prefer journal accounts, accounts for specific subject areas? Please do share your thoughts in the quote posted thread!

Got the chance to put together the "Click of Chemical Biologists" starter pack v1 and v2 over the Thanksgiving Break. Feel free to ping me on who else I might be missing! V1: go.bsky.app/3P5i7nJ V2: go.bsky.app/Cr4ej7

Thrilled to share our study on the two DUBs USP53 and USP54! If you're curious about how biochemistry, chemical biology, crystallography, and ubiquitinated protein isolation came together to expand our understanding of these enzymes, consider to give it a read.

As a first post, we're excited to announce Profs. Zoƫ Waller (UCL) and Sandy Schmidt (University of Groningen) as plenary lectures at the 2025 RSC Chemical Biology and Bio-Organic Group (CBBG) Forum in Bristol on 18th Februrary! www.rsc.org/events/detai... Deadline for abstracts is 6th December

The strain on scientific publishing: we set out to characterise the remarkable growth of the scientific literature in the last few years, in spite of declining growth in total scientists. What is going on? direct.mit.edu/qss/article/... A šŸ§µ 1/n #AcademicSky #PhDchat #ScientificPublishing #SciPub

We are looking for two #postdocs to join us: 1) @ERC_Research funded position in the context of RNA origami, cryoEM, synthetic cells, directed evolution; 2) A position in the excellence cluster @Cluster3DMM2O at the interface of chemistry & biology. Please share and get in touch!

šŸŽØ In case anyone needā€¦ The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool šŸ™! Check it out šŸ‘‡ bioart.niaid.nih.gov

Join our team as a PhD researcher in Biomaterials for Neural Regeneration as part of our multi-partner center Interreg funded by @CZ_Stiftung the full call is here. www.nature.com/naturecareer... more details on our position: www.walther-group.com/job-openings... #phdjobs #chemjobber #PhD #chemsky

Facts matter. Science saves lives. Anti-science destroys them.

In our new work, we identified 2 phosphatases, PP1 & PP5, to dephosphorylate the co-chaperone BAG3 regulating the process of chaperone-assisted selective autophagy to maintain cellular proteostasis: www.life-science-alliance.org/content/8/2/... Thanks everyone involved for this great collaboration!

We are working on the program for the 5th Virtual ChemBioTalks on September 30th, 2025. While we already have commitments by our keynotes @oconnorlab.bsky.social and @craigmcrews.bsky.social, the remaining program is still in planning. Whom would you most like to hear at our next event?

Welcome to all chemical biologists on Bluesky! If youā€™re signed up as a Fachgruppe Chem Bio member, or are coming to our ChemBio Advances conference in 2025, please reply to this post so we can add you. Keep up the #ChemBio hashtag and see you on 21-22 Jan in Frankfurt! dechema.de/en/ChemBio20...

Attn Chemical Biology community in Germany / Switzerland / Austria: I unofficially made @gfg-chembio.bsky.social for our Gemeinsame Fachgruppe Chemische Biologie. Please follow! Hopefully, one day it can be a hub for all GFG-CB members & speakers at our Advances in Chemical Biology conference.