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molinalab.bsky.social
Group leader of the Stochastic Systems Biology Lab at IGBMC - CNRS - University of Strasbourg. Models of gene regulation based on biophysics-informed deep learning: https://www.igbmc.fr/molina
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Making intrabodies from antibodies just got easier! Learn how we made 𝟭𝟵 intrabodies to bind and light up peptides and histone modifications in live cells. And thanks to Academia, all sequences are freely available. (video credit: Yuko Sato @YukoSatoT2) (1/15) www.biorxiv.org/content/10.1...

submitted 14 days ago • 12 comments

Friday Lectures – Giacomo Cavalli Join us on Friday, 7th February at 3pm for a talk by Giacomo Cavalli, expert in Polycomb regulation and 3D genome architecture. He’ll explore how these mechanisms affect epigenetic inheritance and cancer development. Don’t miss it! #Epigenetics #Genomics #Cancer

submitted 22 days ago • 0 comments

Come join us for this very first conference on single molecule approaches (both omics et imaging) to understand gene expression regulation. Lots of slots for young selected speakers!

submitted 39 days ago • 0 comments

The next TriRhena Gene Regulation Club takes place at IGBMC #Strasbourg. Save your seat & submit a talk. Strengthen your local #epigenetics network & collaborate with peers. 📅 5 Feb. 2025 | 14:00 🎟️ Free entry, registration required ✍️ Register by: 24. Jan. www.ie-freiburg.mpg.de/gene-regulat...

submitted 43 days ago • 1 comment

We often speak about chromatin as being accessible or inaccessible, but what does it mean? We wrote a short review on this, 🔬 focused: sciencedirect.com/science/arti... A big thank you to Tom Fillot for his efforts on this and to @hansen_lab @marcelonollmann for their help as editors.

submitted 67 days ago • 4 comments

submitted 78 days ago • 2 comments

1/ One more preprint before the holidays! In which we find that chromatin compaction scales with cell size from interphase through mitosis. A collaboration from waaay back (see end of thread) with Melike Lakadamyali @melikel.bsky.social and Jerome Solon. A thread: 👇 www.biorxiv.org/content/10.1...

submitted 78 days ago • 1 comment

Gene regulation is more complex than you think, even in bacteria! Check out the preprint from the PhD work of Luca Galbusera. TLDR: Within single cells, transcription factor (TF) levels can undergo large transient changes that occur on the same time-scale as 1/n www.biorxiv.org/content/10.1...

submitted 84 days ago • 1 comment

#paperalert! In our new study, we ask the question: Can we predict RNA stability across conditions and protocols, based solely on experimental and/or computationally predicted RNA binding protein target sites? Read the paper to find out ! www.biorxiv.org/content/10.1...

submitted 84 days ago • 1 comment

Any RNA biologists in the room? Does this makes sense? Is your favourite RBP in the list? #RNAbiology #RNAexport #RNAstability

submitted 85 days ago • 0 comments

Huge effort resulting in improved TF binding site models. Congrats to the winners but also all participants for pushing analytical borders and finally also to Vanja Kulakovskiy @halfacrocodile.bsky.social‬ & team for organizing it all!

submitted 87 days ago • 0 comments

We' re #hiring a #postdoc in my team at @pasteur.fr and @cnrs.bsky.social funded by Institut PRAIRIE to work on the inference of molecular mechanisms from the integration of spatial transcriptomics and #singlecell multi-omics data. Learn more at emploi.cnrs.fr/Offres/CDD/U...

submitted 91 days ago • 1 comment

Our research institute I2SysBio🇪🇸 has created a starter pack for researchers in systems biology, everybody is welcome, write us if you want to be added 🔬🧫🧬🖥🦑🦠🌱🦟🪳🪸🌾

submitted 97 days ago • 10 comments

Look who's here @pnas.org ✔️ @science.org ✔️ @naturecellbiology.bsky.social ✔️ @natrevgenet.bsky.social ✔️ @naturebiotech.bsky.social ✔️ @naturemicrobiol.bsky.social ✔️ @naturechemistry.bsky.social ✔️ @genesdev.bsky.social ✔️ @cellchembiol.bsky.social ✔️ @genomeresearch.bsky.social ✔️ @jcellbiol.bsky.social ✔️

submitted 93 days ago • 34 comments

We've now filled one #Epigenetics, Chromatin and Gene regulation starter pack. Thanks for all the enthusiasm and support, if you'd like to be listed @raduzabet.bsky.social has been hard at work getting part II up and running: go.bsky.app/SqLa3aw

submitted 92 days ago • 25 comments

Here’s the updated Computational Biology Starter Pack! Let me know if you'd like to be included. go.bsky.app/QVPoZXp

submitted 93 days ago • 82 comments

Hey, this place is getting fun! Here is a new version of our latest preprint on oscillatory dynamics of mRNA metabolism and chromatin accessibility during the cell cycle: www.biorxiv.org/content/10.1...

submitted 96 days ago • 5 comments

Nacho Molina reveals beautiful cyclic gene expression patterns in scRNA/ATAC data @molinalab.bsky.social #EMBLOmics

submitted 96 days ago • 1 comment

First #jobalert on Bluesky! Postdoc (or PhD position with strong ML background), for a joint project with Gregoire Montavon’s lab at #BIFOLD #TU-Berlin . Topic is explainable AI /ML for self supervised LLMs in multi/spatial omics & gene regulation. www.jobs.tu-berlin.de/stellenaussc...

submitted 98 days ago • 1 comment

My favourite place for conferences!

submitted 99 days ago • 1 comment

Happy to share @cecerelab.bsky.social mooc on epigenetics. My small contribution was focused on the only important aspect of this word (😂)…. WHAT DO YOU THINK WE ARE SPEAKING ABOUT? I ❤️ semantics www.fun-mooc.fr/en/courses/e...

submitted 99 days ago • 0 comments

In case you don't have anything to read for the weekend, here is a suggestion: (#FunFridayReading I hope 🙄) 👇 www.biorxiv.org/content/10.1...

submitted 390 days ago • 0 comments

Hey! Check out our latest work, a result of a stimulating collaboration with @longchrom. Hope you like it! We'd love to hear your feedback and comments. 👇

submitted 391 days ago • 0 comments

Hi, first real post here... Our latest! In which we suggest that cells monitor individual RNA synthesis rates and fine-tune their splicing, export and degradation rates to maintain gene-specific RNA homeostasis. Comments / criticisms welcome! Explainer below. #OurFirstGenomicsPreprint

submitted 391 days ago • 1 comment