planetaoptimism.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

Today, in the direction of Kostyantynivka, Russians attempted an unusually large-scale mechanized assault, which is not typical nowadays. As a result, Russians lost 15 units of heavy equipment. t.me/Zigun_Mangus...

submitted 11 hours ago • 2 comments

⚫Bernard Lacombe, légende du foot lyonnais est mort à 72 ans

submitted 11 hours ago • 1 comment

Omega-3 Fatty Acid Synergy with Glucocorticoid in Lupus Macrophages: Targeting Pathogenic Pathways to Reduce Steroid Dependence https://www.biorxiv.org/content/10.1101/2025.06.12.658906v1

submitted 9 hours ago • 0 comments

Succinate enhances mitochondrial metabolism and phagocytosis in human airspace monocytes https://www.biorxiv.org/content/10.1101/2025.06.12.659271v1

submitted 9 hours ago • 0 comments

Preparation of Scutellariae Radix and Corn-Soy Peptides Complex and Its Hepatoprotective Mechanisms https://www.biorxiv.org/content/10.1101/2025.06.12.659390v1

submitted 8 hours ago • 0 comments

good people of here. democracy and the citizens of Ukraine need your help. a donation today keeps the fascism away. :)

submitted 14 hours ago • 0 comments

(Reuters) - The Trump administration shelved in recent weeks an inter-agency working group it had set up to formulate strategies for pressuring Russia into speeding up peace talks with Ukraine, according to three U.S. officials. www.reuters.com/world/asia-p...

submitted 20 hours ago • 9 comments

New—Prevalence of #clinical #obesity versus #BMI-defined obesity among US adults: a cohort study thelancet.com/journals/lan... #FREE to read #MedSky #EndoSky

submitted 1 day ago • 0 comments

A direct hit by a Russian-Iranian drone on a Kyiv apartment building this morning 🤬

submitted 23 hours ago • 14 comments

Guerre en Ukraine : au moins 14 morts à Kyiv après l’une des attaques russes les plus meurtrières sur la capitale Les frappes ont duré près de neuf heures et mobilisé un grand nombre de drones d’attaque kamikazes ainsi que des missiles de croisière

submitted 23 hours ago • 1 comment

Anthracyclines induce global changes in cardiomyocyte chromatin accessibility that overlap with cardiovascular disease loci https://www.biorxiv.org/content/10.1101/2025.06.11.658997v1

submitted 1 day ago • 0 comments

NEW: Trump says “everyone should immediately evacuate Tehran"

submitted 1 day ago • 10 comments

Kathleen Spangler, a 29-year-old U.S. Marine Corps officer, only vaguely remembered buying a few tickets in an online raffle back in December. Six months later, she got a text from a friend asking, “By chance, did you win a cottage in Ireland?” nyti.ms/4ebfpZe

submitted 1 day ago • 80 comments

Proteomic and metabolic profiling reveals APOE4-dependent shifts in whole brain, neuronal, and astrocytic mitochondrial function and glycolysis https://www.biorxiv.org/content/10.1101/2025.06.15.659811v1

submitted 1 day ago • 0 comments

Trump displays his lies. 1. Russia was expelled by all for its war of aggression against Ukraine in March 2014. 2. The war has continued ever since because the West did not arm Ukraine. 3. Clearly, Trump condones Putin's war on Ukraine.

submitted 1 day ago • 10 comments

MOLECULARss HYDROGEN THERAPY: A “DEMOCRATIC” EMERGING STRATEGY AGAINST AGING AND AGE-RELATED DISEASES www.sciencedirect.com/science/arti...

submitted 2 days ago • 0 comments

#Mitochondria in oxidative #stress, #inflammation and #aging: from mechanisms to therapeutic advances Xieyang Xu, Yan Pang & Xianqun Fan www.nature.com/articles/s41...

submitted 2 days ago • 0 comments

This review discusses how mitochondrial #bioenergetic failure, dynamic abnormalities, and mitophagic dysfunction interact with aging processes to drive #ParkinsonsDisease progression, and highlights potential therapeutic strategies targeting #mitochondrialpathways. #medsky buff.ly/BVasqEu

submitted 2 days ago • 0 comments

Nutritional iron deficiency elicits profound rewiring of red pulp macrophage functions via high FPN and SYK-mediated signaling https://www.biorxiv.org/content/10.1101/2025.06.13.659526v1

submitted 2 days ago • 0 comments

Proximal Pulmonary Artery Stiffening as a Biomarker of Cardiopulmonary Aging https://www.biorxiv.org/content/10.1101/2025.06.10.658632v1

submitted 2 days ago • 0 comments

🚨Last week's #immunometabolism findings @biomednews.bsky.social 🔽🔽🔽 biomed.news/bims-imicid/... Interesting paper: Glucose-1-phosphate promotes compartmentalization of glycogen with the pentose phosphate pathway in CD8+ memory T cells

submitted 3 days ago • 0 comments

Excellent explanation of biochemical processes in the human body. youtu.be/lYIBNUyMpI4?...

submitted 2 days ago • 0 comments

Mitochondrial Bioenergetic Failure in SLE Immunocytes: Targeting Fitness for Therapy https://www.biorxiv.org/content/10.1101/2025.06.10.658845v1

submitted 3 days ago • 0 comments

A computational analysis of the glycoprotein LRP1 structure and the role of glycans as quaternary glue https://www.biorxiv.org/content/10.1101/2025.06.10.658798v1

submitted 3 days ago • 0 comments

PHOTOS: Police have issued a dispersal order and fired tear gas during a "No Kings" protest in LA, as 2,100 cities and towns across the U.S. held anti-Trump demonstrations today.

submitted 3 days ago • 25 comments

Multiple central banks are set to keep interest rates frozen in the coming week while continuing to gauge the impact of trade disruptions instigated by US President Donald Trump.

submitted 3 days ago • 4 comments

The presidential parade scene in Idiocracy (2006). youtu.be/aeXge9S4-3g?...

submitted 3 days ago • 17 comments

Large crowds across the U.S. gathered on Saturday to protest the Trump administration. See photos from the “No Kings” rallies here. www.nytimes.com/2025/06/14/u...

submitted 3 days ago • 92 comments

Israel’s latest wave of attacks on Iran took out Tehran’s main gas depot and its central oil refinery in separate parts of the capital, engulfing its sky in smoke and flame early Sunday. www.nytimes.com/2025/06/14/w...

submitted 3 days ago • 19 comments

⚽ La Coupe du monde des clubs pourrait n’être qu’une compétition de plus, vaguement exotique. Ce qui en fait le sel, c’est que des clubs rejetés dans les limbes de la mondialisation du football se voient enfin offrir des possibilités de confrontations. Billet :

submitted 3 days ago • 2 comments

The outstanding investigative Russian journalist & Putin critic Anna Politkovskaya was murdered on Putin's birthday in 2006 (October 7). Minnesota Rep. Melissa Hortman was killed in a "politically motivated assassination" (Mike Walz) on Trump's Birthday (June 14).

submitted 3 days ago • 10 comments

Titania Nanoparticle Regulate Innate Immunity https://www.biorxiv.org/content/10.1101/2025.06.13.658543v1

submitted 4 days ago • 0 comments

Nature research paper: Early life high fructose impairs microglial phagocytosis and neurodevelopment https://go.nature.com/3HGv4na

submitted 4 days ago • 0 comments

Russian military convoy was struck by a HIMARS early this morning near Donetsk during personnel transportation. All vehicles involved have black military license plates. At least one body of a Russian soldier in uniform is visible near the convoy. Preliminary reports mention up to 20 killed.

submitted 4 days ago • 15 comments

Nature research paper: Metabolic adaptations direct cell fate during tissue regeneration https://go.nature.com/4l4GP5c

submitted 5 days ago • 0 comments

Garlic-Derived Allicin Modulates Expression of the SARS-CoV-2 Spike Receptor-Binding Domain in Human Splenic Fibroblasts https://www.biorxiv.org/content/10.1101/2025.06.10.659002v1

submitted 5 days ago • 0 comments

A federal judge issued an order late Thursday blocking President Trump from deploying members of the California National Guard in Los Angeles, and ordered the administration to return control of the forces to Gov. Gavin Newsom. Follow live updates. trib.al/GYviSzG

submitted 5 days ago • 62 comments

🚨 BREAKING: The head of Iran's Revolutionary Guard Hossein Salami was killed in the Israeli strike, state media report. Follow our blog for the latest news, updates and analysis ⤵️

submitted 5 days ago • 17 comments

www.sciencedirect.com/science/arti...

submitted 5 days ago • 0 comments