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planetaoptimism.bsky.social
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A 110-million-year-old dinosaur fossil found in Alberta, Canada.

submitted 17 hours ago • 2 comments

New Zealand farms are piloting a low-cost solution to reduce climate pollution from cattle.

submitted 3 hours ago • 5 comments

If you had asked ChatGPT you would not have gotten that answer.

submitted 2 hours ago • 3 comments

The role of NAD+ metabolism and its modulation of mitochondria in aging and disease www.nature.com/articles/s44...

submitted 18 hours ago • 0 comments

#VitaminD deficiency and myocardial #ATP depletion are associated with #heartfailure. www.sciencedirect.com/science/arti...

submitted 1 day ago • 0 comments

Fatty Acid Synthase Regulates Glucose and Energy Homeostasis via POMC neurons and Adrenergic Signals www.sciencedirect.com/science/arti...

submitted 1 day ago • 0 comments

Timothy Snyder's remarks on the importance of coalitions are interesting in light of Saturday's combined protest in Boston.

submitted 3 days ago • 17 comments

Beyond Energy Metabolism: Ketogenic Diet and β-Hydroxybutyrate Protect Against Intestinal Ischemia-Reperfusion Injury Through Anti-inflammatory and Barrier-Preserving Effects www.sciencedirect.com/science/arti...

submitted 1 day ago • 0 comments

Not much seems to faze the stock market these days even as risks abound, from war in the Middle East, to trade tensions, to slowing growth. But Wall Street’s biggest fear arrives today when the Federal Reserve meeting ends and Chair Jerome Powell explains the central bank’s outlook.

submitted 1 day ago • 2 comments

Ketone body driven lipid remodeling supports thermogenic adaptation to fasting https://www.biorxiv.org/content/10.1101/2025.06.13.659540v1

submitted 1 day ago • 0 comments

Today, in the direction of Kostyantynivka, Russians attempted an unusually large-scale mechanized assault, which is not typical nowadays. As a result, Russians lost 15 units of heavy equipment. t.me/Zigun_Mangus...

submitted 2 days ago • 4 comments

⚫Bernard Lacombe, légende du foot lyonnais est mort à 72 ans

submitted 2 days ago • 1 comment

Omega-3 Fatty Acid Synergy with Glucocorticoid in Lupus Macrophages: Targeting Pathogenic Pathways to Reduce Steroid Dependence https://www.biorxiv.org/content/10.1101/2025.06.12.658906v1

submitted 2 days ago • 0 comments

Succinate enhances mitochondrial metabolism and phagocytosis in human airspace monocytes https://www.biorxiv.org/content/10.1101/2025.06.12.659271v1

submitted 2 days ago • 0 comments

Preparation of Scutellariae Radix and Corn-Soy Peptides Complex and Its Hepatoprotective Mechanisms https://www.biorxiv.org/content/10.1101/2025.06.12.659390v1

submitted 2 days ago • 0 comments

good people of here. democracy and the citizens of Ukraine need your help. a donation today keeps the fascism away. :)

submitted 2 days ago • 0 comments

(Reuters) - The Trump administration shelved in recent weeks an inter-agency working group it had set up to formulate strategies for pressuring Russia into speeding up peace talks with Ukraine, according to three U.S. officials. www.reuters.com/world/asia-p...

submitted 2 days ago • 9 comments

New—Prevalence of #clinical #obesity versus #BMI-defined obesity among US adults: a cohort study thelancet.com/journals/lan... #FREE to read #MedSky #EndoSky

submitted 2 days ago • 0 comments

A direct hit by a Russian-Iranian drone on a Kyiv apartment building this morning 🤬

submitted 2 days ago • 14 comments

Guerre en Ukraine : au moins 14 morts à Kyiv après l’une des attaques russes les plus meurtrières sur la capitale Les frappes ont duré près de neuf heures et mobilisé un grand nombre de drones d’attaque kamikazes ainsi que des missiles de croisière

submitted 2 days ago • 1 comment

Anthracyclines induce global changes in cardiomyocyte chromatin accessibility that overlap with cardiovascular disease loci https://www.biorxiv.org/content/10.1101/2025.06.11.658997v1

submitted 3 days ago • 0 comments

NEW: Trump says “everyone should immediately evacuate Tehran"

submitted 3 days ago • 10 comments

Kathleen Spangler, a 29-year-old U.S. Marine Corps officer, only vaguely remembered buying a few tickets in an online raffle back in December. Six months later, she got a text from a friend asking, “By chance, did you win a cottage in Ireland?” nyti.ms/4ebfpZe

submitted 3 days ago • 80 comments

Proteomic and metabolic profiling reveals APOE4-dependent shifts in whole brain, neuronal, and astrocytic mitochondrial function and glycolysis https://www.biorxiv.org/content/10.1101/2025.06.15.659811v1

submitted 3 days ago • 0 comments

Trump displays his lies. 1. Russia was expelled by all for its war of aggression against Ukraine in March 2014. 2. The war has continued ever since because the West did not arm Ukraine. 3. Clearly, Trump condones Putin's war on Ukraine.

submitted 3 days ago • 10 comments

MOLECULARss HYDROGEN THERAPY: A “DEMOCRATIC” EMERGING STRATEGY AGAINST AGING AND AGE-RELATED DISEASES www.sciencedirect.com/science/arti...

submitted 3 days ago • 0 comments

#Mitochondria in oxidative #stress, #inflammation and #aging: from mechanisms to therapeutic advances Xieyang Xu, Yan Pang & Xianqun Fan www.nature.com/articles/s41...

submitted 3 days ago • 0 comments

This review discusses how mitochondrial #bioenergetic failure, dynamic abnormalities, and mitophagic dysfunction interact with aging processes to drive #ParkinsonsDisease progression, and highlights potential therapeutic strategies targeting #mitochondrialpathways. #medsky buff.ly/BVasqEu

submitted 4 days ago • 0 comments

Nutritional iron deficiency elicits profound rewiring of red pulp macrophage functions via high FPN and SYK-mediated signaling https://www.biorxiv.org/content/10.1101/2025.06.13.659526v1

submitted 4 days ago • 0 comments

Proximal Pulmonary Artery Stiffening as a Biomarker of Cardiopulmonary Aging https://www.biorxiv.org/content/10.1101/2025.06.10.658632v1

submitted 4 days ago • 0 comments

🚨Last week's #immunometabolism findings @biomednews.bsky.social 🔽🔽🔽 biomed.news/bims-imicid/... Interesting paper: Glucose-1-phosphate promotes compartmentalization of glycogen with the pentose phosphate pathway in CD8+ memory T cells

submitted 5 days ago • 0 comments

Excellent explanation of biochemical processes in the human body. youtu.be/lYIBNUyMpI4?...

submitted 4 days ago • 0 comments

Mitochondrial Bioenergetic Failure in SLE Immunocytes: Targeting Fitness for Therapy https://www.biorxiv.org/content/10.1101/2025.06.10.658845v1

submitted 4 days ago • 0 comments

A computational analysis of the glycoprotein LRP1 structure and the role of glycans as quaternary glue https://www.biorxiv.org/content/10.1101/2025.06.10.658798v1

submitted 5 days ago • 0 comments

PHOTOS: Police have issued a dispersal order and fired tear gas during a "No Kings" protest in LA, as 2,100 cities and towns across the U.S. held anti-Trump demonstrations today.

submitted 4 days ago • 25 comments