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pombase.bsky.social
https://www.pombase.org/ Knowledgebase for Schizosaccharomyces pombe (a fission yeast). Supporting scientific discovery for cell-level processes; #OpenScience, #FAIR data #CommunityCuration; Monitoring #UnknownProteins; Elixir and GBC Core Data Resource.
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Prolific Poster

🧬 Now you can access @sevaplasmids.bsky.social directly from #OpenCloning ✨. 🔗 try it: opencloning.org 🎞️ demo: youtu.be/n0hedzvpW88?...

🧬🔬 Ever wondered if there’s a #GateWay plasmid in @addgene.bsky.social with GFP and the att sites you need? 🤔✨ Wonder no more! 🚀 Visit GateWayMine to search a database of #AddGene plasmids by feature or site type! 🧪🔍 🔗 gatewaymine.netlify.app More context in the thread! 🧵👇

PomBase is GBC Global BioData Resource of the week www.linkedin.com/pulse/pombas...

The Trump NIH is banning hires of new students and postdocs. This is devastating for NIH research and will result in a lost generation of researchers at the institution. Heard from a applicant today: "A lot of people are banking their entire careers on the [NIH student programs]..." #NIH 🧪 1/

Some federal employees who accepted Trump’s buyout offer are now being notified that their buyout has been denied, and they are being terminated instead.

Just talked to a friend whose spouse is a contractor for the VA. They are worried about their job and their future. But what shocked me was that they had no clue what happened at NIH, USDA, CDC, NOAA. The word is simply not getting out. The average American just doesn't know.

San Diego:: BE THERE

I have turned the primer designer of #OpenCloning into a stepper after feedback from lab members and @francescodb.bsky.social. It now conveys more clearly the workflow. Below an example of #primerDesign for #GatewayCloning 🔗 try it: opencloning.org 🎞️ demo: www.youtube.com/watch?v=n0he...

📢 #Yeast2025 News! Registration and abstract submission are NOW OPEN! Join us at the 32nd ICYGMB 📅 Save the Date: 21-24 July 2025 📍 Location: Paris @sorbonne-universite.fr 🔗 Submit: premc.org/yeast2025/su... 🕒 Register now to take advantage of the Early Bird fee premc.org/yeast2025/re...

Officially pulled the plug on @LusKingL on X as well as academic accounts I managed. May the community continue to grow and thrive here!

www.sciencealert.com/this-fungus-...

v3.0.0 is coming soon to @pombase.bsky.social !

🔍 Lost in InterPro data? Our redesigned Help page has you covered! From quick answers to deep dives into protein families, find exactly what you need at www.ebi.ac.uk/interpro/help/ 💻🧪

The majority of people who responded to a poll in Nature say they’re now using Bluesky. They’re using it to connect with other scientists, keep up to date with other research or researchers, and promote their own research. 🧪

The new POMBOX kit is now available from @addgene.bsky.social To plan your cloning with this and other Golden Gate kits, you can try the kit template in #ShareYourCloning 🔗 Visit shareyourcloning.org 👉 Go to Templates > Moclo 🎞️ Full demo video www.youtube.com/watch?v=n0he... #pombe #MoClo

Centromere evolution isn't a sudden switch! Our study shows centromere transitions are a step-by-step process driven by a combination of drift and selection. Discover how the kinetochore interface shapes this gradual change in our new preprint 🥳 doi.org/10.1101/2025.01.16.633479 🧵(1/8)

Since April, we have been busy curating pathways using GO-CAM pathway modelling. So far, 466 proteins (33 pathways) have been modelled. We have modelled signalling pathways, metabolic pathways, and other processes. The full list is here: www.pombase.org/documentatio..., and will increase weekly!

Nitrogen-starvation of #FissionYeast inactivates growth pathways (incl TORC1) & can trigger sexual reproduction. @sophiemartinlab.bsky.social use proteomic & phosphoproteomic changes during sexual development to show that TORC1 is reactivated by pheromone signaling 🧪 @plosbiology.org plos.io/4h3OUVO

Nitrogen-starvation of #FissionYeast inactivates growth pathways (incl TORC1) & can trigger sexual reproduction. @sophiemartinlab.bsky.social use proteomic & phosphoproteomic changes during sexual development to show that TORC1 is reactivated by pheromone signaling 🧪 @plosbiology.org plos.io/4h3OUVO

Our lab has multiple open positions for post-docs to study the regulation and function of cytoplasm mechanics during embryo development. Details below 👇👇 Please Repost !!! @ijmonod.bsky.social @cnrs.bsky.social

Happy to join Bluesky! We have news for friends of RNA in fission and budding yeast - our census of RNA-dependent proteins is online: www.biorxiv.org/content/10.1... We are using R-DeeP (pioneered by @maiwen-ch.bsky.social) @pombase.bsky.social & @yeastgenome.bsky.social (1/n)

Do you know where transcription of a gene actually stops? Hint: it is not the annotated gene end. In our new paper in Nucleic Acids Research we argue that phosphorylation on threonine 4 of RNA Pol II CTD is a marker of transcription termination in animals... 🧵 academic.oup.com/nar/advance-...

Double whammy: Wellcome Centres are no more & MRC Units are on their last funding cycle. Huge blow to science in cities other than Cambridge-Oxford-London which continue to have well-funded institutes with excellent infrastructure (Crick, LMB etc). The rest of us…? www.science.org/content/arti...

Thank you to @manu-lera.bsky.social for creating the videos and docs, and to our amazing community for providing >25,000 ontology-based annotations from small scale papers, check out some highlights here: www.pombase.org/archive/spot...

Reminder, if you are yeast biologist (species agnostic, just need be single celled and a fungus) please let me know and I will add you to this starter pack. go.bsky.app/PyUwqLU

OK Pinterest, I see where you are coming from

Hi Bluesky community! 👋 Are you looking forward to 2025 as much as we are? 👀 We just updated our 2025 Annual Poster to include even more events for you to join, so go and have a look! ➡️ s.embl.org/poster-bl #EMBLEvents #molecularbiology #lifesciencetraining

There is competitive #PhD funding for 4 years (eligibility criteria apply) to do a project on the human pathogen Candidozyma (Candida) auris dissecting the genetic basis of its antimicrobial resistance #AMR www.findaphd.com/phds/project... - pls repost

Proofs!

EXTRA! EXTRA! Read all about it! Latest SGD newsletter! www.yeastgenome.org/blog/sgd-new... - AlphaFold - YeastMine - Community wiki - SGD’s new GENETICS publication - New yeast microPublications - Alliance of Genome Resources 7.4 - Give a Gift/Support SGD - Upcoming conferences - Happy Holidays!

૮˶• ﻌ •˶ა ./づ~ 🦴 @pombase.bsky.social have you guys seen this?

🎁 Day 7 of our #AdventCalendar Did you check out our 2024 course on #RNASeq – Data readiness for #machinelearning applications? Developed by Ed Parkinson at Cardiff University fellowship.elixiruknode.org/latest/carpe...

Are you looking for fungi funding? 🍄 We’re offering up to £3 million per award to research how fungi adapt to their environment. Understanding this could have powerful benefits for human life and health. Apply by 28 January ⤵️ wellcome.org/grant-fundin...

@avrahamcoopermd.bsky.social why nor share w/ your followers here on 🔵bsky your 𝕏eet from Dec 26, 2022 ? "Who knew that the Pyruvate Dehydrogenase Complex actually resembles a pub brawl?" we love it! 😄

Don't miss this paper published today in Nature Comm. in which I have been lucky enough to participate, a beautiful work! @pombase.bsky.social @interibfg.bsky.social @csic.es @usaloficial.bsky.social www.nature.com/articles/s41...

After a 15 year search: The oncogene SLC35F2 is a high-specificity transporter for the micronutrients queuine and queuosine biorxiv.org/cgi/content/short/2024.12.03.625470v1 (it's fission yeast SPCC320.08). Congrats to Valerie Crecy-Lagard @annehrenhofer.bsky.social & Co.

We are looking for a Postdoc in Functional Genomics who will apply large-scale genetic assays, functional profiling, and systemic/computational approaches to examine the roles of conserved yet unstudied proteins, focusing on cellular quiescence and ageing. www.ucl.ac.uk/work-at-ucl/...

OMG that's how it works!

A video showing the #Gateway cloning #PrimerDesign tool of #ShareYourCloning. If you are a user of Gateway, I would appreciate your feedback. 🔗 try it at shareyourcloning.org www.youtube.com/watch?v=-wjO...

Congratulations, very well deserved, a great anti-ageing strategy too ;)!

1st post on bsky - about bsky! I was fascinated with academic starter packs and made an interactive network to see academic communities and how they connect - a map of knowledge! link to an interactive & searchable network: ketikagarg.github.io/blueSkyAcade...

Please consider signing and sharing. We need new funding models for resources, the GBC are leading the way. Funders on board globalbiodata.org/membership/m... governments may also need convincing...

'But a new systematic analysis of what some call the “dark proteome” suggests scientists have missed thousands of nontraditional genes that lurk in previously overlooked stretches of the genome and make smaller than average proteins.' www.science.org/content/arti...

Had a great time presenting and chatting at this month's Nuclear Pore, Nuclear Envelope and Nucleocytoplasmic Trafficking Virtual Workshop! My talk is here if you missed it! www.youtube.com/watch?v=0cfQ...

@pombase.bsky.social now using InterPro release 103.0, with the update to Pfam 37.1. It was a little slower than usual because our developer has COVID 😷.

InterPro release 103.0 is live! 💻🧪 ✨Update to Pfam 37.1 ✨1029 new entries, including 1019 signatures from the Pfam (1008), NCBIfam (2), PIRSF (1), PANTHER (1), CDD (7) databases. Have a look: ebi.ac.uk/interpro/