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profriggins.bsky.social
she/her. Assoc Prof, AD Educ & Training @LombardiCancer. #lobular, HER2+/ER+ BrCa, #nuclearreceptors, #GBM. Co-founder @nrimpact.bsky.social. When not sciencing, I'm enjoying ⛵️⛺️🏋🏻‍♀️🏃🏻‍♀️🥃 Skeets my own
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Online Now: Balancing metabolism and regeneration in liver diseases through HNF4α targeting #trends #endocrinology #metabolism

Finalized the collection "Methods and Models in Mammary Gland Biology and Breast Cancer" with @sumbalovakoledova.bsky.social for Journal of Mammary Gland biology and Neoplasia. Check out our editorial on the articles included in the colection 🧪 link.springer.com/article/10.1...

1/ 🧬 A Hitchhiker’s Guide to Long-Read Genomic Analysis is out now! This mini-review walks through the latest advances in long-read DNA sequencing — from assemblies to variant calling to epigenetics. Link 🔗 genome.cshlp.org/content/35/4... 🧵👇

How can we bridge observational spatial biology with functional characterization—bringing together experts in spatial, systems, and synthetic biology! Join NCI for virtual workshops on May 13, 15, & 20 (12:00–4:30 PM ET) 📅 Register: events.cancer.gov/nci/syntheti... #SynSysBio4SpatialCancerResearch

“How might the narrative about senior women be challenged or changed in order to respect these women who have achieved enough success to earn promotion? How do we stop this generational cycle so that women's wings aren't clipped as soon as they approach the power to soar.”

Me: ok gotta start eating better, no more stress cookies The news: 👋hey Me: I could use a donut

Welp, it begins. Sigma Aldrich.

The Senate Committee on Appropriations is holding a hearing on Biomedical Research: Keeping America’s Edge in Innovation on April 30 at 10:30am ET, chaired by Senator Susan Collins 🧪 www.appropriations.senate.gov/hearings/bio...

Today we welcomed students from Washington School for Girls as part of our Maker Girls program! 👩‍🔬 Thanks to Infosys Foundation USA, these young women are building hands-on skills with our Invent the Future Challenge. Maker Girls will showcase their work at our Invent the Future Expo on June 1!🚀

Academic senate of the University of Illinois resolves to join the Big 10 mutual defense compact! Proud to have been a co-signer of a great resolution put forward by @gipperfish.bsky.social

Come be my colleague! Open-rank tenure-line position(s) in cancer cell bio/pharmacology/biochemistry at Georgetown University apply.interfolio.com/167091 🧪🧬 👩‍🔬

oh my god

Losing my grant doesn’t make me worried that having it on my resume will hurt my career. Rather, I worry about what it means for science, I worry about it means for the active work I do and will KEEP doing to uplift, I worry about what it means for upcoming and future scientists.

Even as someone who has followed everything going on at the NIH very closely, this story made my heart sink. I hope Americans watch this and see the impact of shutting down science. This effects everyone.

Come see Kristen Young present her poster at 9:00 this morning! She shows how inhibiting immunosuppressive paracrine signaling with an antiestrogen reinvigorates NK cells to improve anticancer activities in ER+ breast cancer cells! @kristen-young.bsky.social #AACR25

"The grant was created by the first Trump administration to foster a new generation of diverse scientists in biomedical research, then defunded in the second Trump administration's ongoing purge of diversity, equity, and inclusion programs." www.wxxinews.org/2025-04-28/a...

🙋‍♀️#46

In its ongoing mission to shrink the federal government, the Trump administration is now proposing a more than 40% budget cut to the National Institutes of Health - the crown jewel of American medical research. 60 Minutes, Sunday.

New Open Build activity this weekend: Paper Making! 📃✨ Dive into the art and science of papermaking! Experiment with blending pulp, forming sheets with 3D-printed molds, and cutting materials to prepare pulp for future projects. Take home your own handmade paper!

This can't be said enough. The narrative is quickly becoming but universities need fed funds, when it should be that the fed govt needs universities. NCI/NIGMS funding to Harvard/MIT supported research that led to the discovery of Herceptin, a cancer drug that has saved 3 million lives to date! 🧪

Scientists must push back against the threat of rising white nationalism and the dangerous and pseudoscientific ideas of eugenics https://go.nature.com/4jGqiUc

Nice story about my running the Boston Marathon for one of our local news orgs. 🏃

I’m hearing that some MOSAIC fellows are not only losing their grants (and for some in the postdoc phase their livelihoods), but also that their LRPs are now being cancelled. To have this population of scientists be targeted in such a manner should be unacceptable to everyone 😤

As a recipient of federal grants from #NIH (for now! 😭) that funds research in my lab, I'd like to sincerely thank American taxpayers on #TaxDay for investing in scientific research that lays the foundation for medical and technological innovation in this country and keeps us all safe and healthy

Georgetown Law celebrates Professor Eloise Pasachoff, who was honored on April 7 with Georgetown University's President’s Award for Distinguished Scholar-Teachers! The award recognizes faculty members for their excellence in teaching and scholarship. Read more: bit.ly/3YynMHr

Some good news from NIH - they have restarted the intramural training programs for postbacs and postdocs. www.training.nih.gov/research-tra...

They are resegregating academic science

I've already had two federal grants terminated and face a 33% pay cut due to future terminations. It's painful, but not as painful as the conversations I'm having every day with brilliant trainees in graduate school and postdoctoral positions who see little future for themselves in US science.

Finally got the notice. Very sad day for the MOSAIC program that supported some of the most amazing scientists I know, as well as some of the awesome people on my lab.

In the midst of everything it feels particularly appropriate to highlight all the amazing #RNA research taking place at #NIH! Follow this thread to join us for our biannual #RNASymposium, this year featuring intramural research superstars!

People let go everywhere you turn at NIH today, carrying in empty boxes. Both the people in the elevator with me. Multiple IC directors. The HR people who are supposed to process all the early retirements. All of the people who respond to data calls that we are legally required to answer.

The only reason I was able to get into research the way I did in Puerto Rico was thanks to RISE. Just another major low kick…

The latest NIH grant chaos: NIH apparently sent stop-work orders to all *97* MARC and U-RISE programs in the country. These programs support underrepresented undergrads interested in health research careers. MARC dates to 1977. Over 48 years, the programs have supported thousands of students.

NIH has rescinded its scientific integrity policy. Hard to see this as anything other than clearing the way for shoddy research on things like vaccines. Regardless of the rationale, it's bad news for public health. grants.nih.gov/grants/guide...

💐 To NIH and NSF program officers, and anyone else trying to keep those institutions alive: Thank you for trying to do an impossible job in an impossible time. I’m sorry for all of us that this is the world we’re living in. 1/n

Unsurprisingly, @tressiemcphd.bsky.social is spot-on in this analysis: “A.I.’s most revolutionary potential is helping experts apply their expertise better and faster. But for that to work, there has to be experts.” www.nytimes.com/2025/03/29/o...

That specifically right there is the sound of science in the US dying

Super nice review on metastasis organo-tropism⬇️ the process where tumor cells preferentially spread to specific distant organs, and represents a critical aspect of cancer biology with profound implications for patient outcomes. #CDH1 www.cell.com/trends/cance...

Today was yet another sad day for science. All U-RISE training programs, including the one at SJSU, got stop work orders. We've had a version of this program at SJSU for 30+ yrs. Devastating for the students who got their stipends & tuition pulled w no notice & for the future of science 🧪 1/