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rasnet.bsky.social
Nonprofit research advocacy org for conditions caused by dysfunctional RAS/MAPK signaling. #rasopathies #raredisease Skeets by Stronach
82 posts 210 followers 272 following
Prolific Poster

Rodent and monkey facilities could be imperiled by the Trump administration’s plan to slash overhead costs that the National Institutes of Health pays to institutions for medical research. scim.ag/3QvS4GC

The annual FDA-NIH Rare Disease Day has been postponed.

Medicaid coverage for virtual visits ends April 1st. As someone who cares for children that live up to 8 hours away, this is DEVASTATING. Children, adults, elderly will all suffer. CALL YOUR REPRESENTATIVES The 5 calls app makes it easy!

Waste clearance from the brain relies on glymphatics, driven by arterial blood flow. What happens in atrial fibrillation? Evidence for impaired glymphatic and cognition function. Open-access @escardio.bsky.social academic.oup.com/eurheartj/ad...

NIH indirects case update & summary of Trump admin’s args: - Trump admin not backing down - Oral argument this Friday, 2/14 - Hearing is to decide whether to extend the block - 1 hearing for all 3 cases Trump admin filed its arguments on Friday. Here’s some of what it’s arguing: 🧵

This is what NIH-funded research leads to. Cures for disease.

Thrilled to share that our work from Trumpp Lab @hi-stem @dkfz.bsky.social is out in Nature. We provide the first single-cell data on neurons infiltrating pancreatic tumors, offering new insights into cancer therapy. #cancerneuroscience @cn-hd.bsky.social www.nature.com/articles/s41...

A two-and-a-half-year-old girl shows no signs of a rare genetic disorder, after becoming the first person to be treated for the motor-neuron condition while in the womb. https://go.nature.com/41a7Zzj

This is not going to help anything. @jeremymberg.bsky.social 🧪

In the day-to-day news blizzard, it can be all too easy to overlook the steady improvements that biomedical research has achieved. The latest American Cancer Society report shows why the work matters. "Since 1970, the cancer death rate has declined by 70% in children and by 63% in adolescents..."

Judge Reyes just became my favorite person.

Recursion CEO Chris Gibson: Publicly funded research built the biopharma industry. Now it needs our help. Companies with resources must bridge the gap. 👏 $RXRX via @statnews.com www.statnews.com/2025/02/19/n...

Please #RT far and wide #DevBio. You may not be aware that we can't have study sections or Council meetings that aren't first published in the Federal Register. The illegal funding freeze is being upheld with this. Thanks @labonnelab.bsky.social! www.thetransmitter.org/funding/fede...

A large portion of grants awarded by the U.S. National Institutes of Health cannot be funded for the foreseeable future because of an indefinite hold on submissions to the Federal Register, according to an email reviewed by The Transmitter. By @avaskham.bsky.social bit.ly/3X8ngz8

Pretty sad. Just got the email that CZI is canceling the second round of Diversity Leadership Awards. Private industry will definitely not fill the hole that NIH and NSF are leaving. 😢💔

ASHG is deeply troubled by the recent layoffs at a number of agencies. The impact on scientific progress and innovation is profound and alarming. Read our statement: www.ashg.org/publications...

Cc: @mollyjongfast.bsky.social

This is a picture of my son taken soon after he was born. I suffered from a very rare pregnancy complication. But thanks to physicians at the University of Michigan and a lot of US funded research, he was born healthy. Please post, who has Science Saved for you? #WhoScienceSaves #MedSky

A vaccination program in Scotland has led to a 62% reduction in hospitalizations for respiratory syncytial virus among older adults, highlighting the vaccine's effectiveness in this age group. doi.org/g85djd

Umbilical cord blood proteins may serve as biomarkers to enhance precision care for preterm infants, potentially improving diagnosis and treatment of complications like infections and sepsis. doi.org/g85dng

Thanks to @motherjones.com for a great piece about the impact of cuts to science funding on our communities and our economy 🧪 www.motherjones.com/politics/202...

It’s so hard to convey impact. The damage being done right now can’t be reversed. Everything that is being lost - it took decades to get there. When labs close, cell lines, libraries of new medicines, genetic models, specialized expertise found nowhere else - it’s just gone. There’s no restart

Mirdametinib is a #MEK inhibitor. 💊 In #NF1 and the #RASopathies, the RAS/RAF/MEK/MAPK pathway is inappropriately activated. MEK inhibition helps to normalize pathway output for therapeutic benefit. 🧪

The shock waves from the Trump administration's assault on the world of science will reverberate for years go come. Progress is being thwarted. Cures are further out of reach. www.statnews.com/2025/02/14/t...

CALL TO ACTION! Our kids who fight cancer battle every day! Today you can do something to help! #fightlikeakid Please email your Representative and Senator today to ask them to show they love our kids by passing the Give Kids a Chance Act. This link makes it easy! www.congressweb.com/KVC/12/

Happy to report that APA wrote this letter, gathered a coalition across science, and will now pay for ads for it to be disseminated in Science and Chronicle of Higher Ed to spread the word!! unitedsciencealliance.org

This week is Seizure Action Plan Awareness Week! Don't delay – take control of your health today by creating your Seizure Action Plan! Download your SAP today, available in seven different languages: sprout.link/epilepsyfdn?...

Alarmingly, RFK Jr has been confirmed. The lone Republican vote against him? Senator Mitch McConnell, a polio survivor. #MedSky #rfk #rfkjr #health #healthcare

This honor is both appreciated and well-earned. Thank you to all the good, kind and brilliant people who make Cincinnati Children's such a special place to work! Improving outcomes together matters now more than ever. #MedSky #PedsSky #childhealth www.cincinnatichildrens.org/news/release...

Positive Clinical Trial Results for a New #FragileX Treatment. Congrats to Dr. Erickson and team! #autism #MedSky scienceblog.cincinnatichildrens.org/positive-cli...

Fantastic! but "Go-mek-li" ?

Great piece with some fantastic quotes from @peiferlabunc.bsky.social and Shirley Tilghman! We need to start educating PIs, trainees, and the general public on what overhead is and what it covers to allow us to do what we do. wapo.st/42RMXrn

Make sure you, your trainees, and anyone else who might listen to you understands what "indirects" actually are, how they are established, and what Universities contribute. H/T @rodallab.bsky.social Please share widely! www.youtube.com/watch?v=yxTD...

AI significantly outperforms human technicians in analyzing long-term ECG recordings, reducing missed severe arrhythmia diagnoses by 14 times, according to a large-scale international study. doi.org/g84mdv

How to get 146% return on investment? The NIH. That's just the economic benefit. Biomedical research promotes human health.

@NIH’s new 15% cap on research funds threatens U.S. science. Call Congress now to oppose it! Your voice matters—act today. Find your rep’s number at govtrack.us. #SupportScience #cellbiology

International Epilepsy Day 💜 Did you know that CACNA1C has been classified as a green (diagnostic evidence level) gene on the Early Onset or Syndromic Epilepsy panels since 2022? These panels are part of the diagnostic pathway to aid in genetic testing. #CACNA1C #EpilepsyAwareness #RareDisease

Today we Celebrate International Epilepsy Day & The Rare Epilepsies! This day encourages everyone, regardless of how they are affected by epilepsy, to advocate for global human rights for people living with epilepsy. www.rareepilepsynetwork.org

A useful tool and a great thing to do... 5calls.org/issue/nih-ns...

Good story about indirect costs from Bruce Lee at Forbes. www.forbes.com/sites/brucel...