sahelisadanand.bsky.social - Profile | ThreadSky | a Reddit-style client for Bluesky

🧵(1/3) Several cool new #braincancer and brain #metastases studies in #NatureMedicine this week! First up, presenting MethyLYZR, a new, super rapid (15 min!) epigenetic sequencing classifier for brain tumors. #NeuroSky #OncSky #MedSky www.nature.com/articles/s41...

submitted 15 minutes ago • 1 comment

💯 Thank you @statnews.com for getting to the heart of the matter and keeping attention on this outbreak when it's already off the front pages of major newspapers. No child has died of measles in this country in decades, this is not normal and the response should be proactive, not dismissive.

submitted 19 hours ago • 0 comments

I talked to NIH officials, current and former, about what's been happening inside the agency since the Trump administration shut down their grantmaking pipeline in January. Their stories showed just how willing our new leaders are to break the law: www.theatlantic.com/health/archi...

submitted 22 hours ago • 20 comments

As the #measles outbreak continues, and has now unfortunately resulted in the death of a child, I see a lot of posts along the lines of: "I had measles as a child and I'm fine". Let me tell you a different version of that story: 🧵1/11 🧪 #medsky

submitted 1 day ago • 10 comments

Local health officials say one child has died of measles - not 2, as RFK claims. RFK downplayed the outbreak, saying people have been hospitalized for quarantine. That's wrong. He said this wasn't unusual, instead of saying it's sad & preventable w/ vaccines. See kffhealthnews.org/news/article...

submitted 1 day ago • 1 comment

Sec. Kennedy, you're incorrect. This is an unusual year for measles. This year has already passed 8 out of the past 15 years' annual counts. And we are only 2.5 months into 2025. Rather than falsehoods, you should publicly state support for MMR. Today marks the first measles death in 10 years.

submitted 1 day ago • 21 comments

Multiple news outlets now reporting that an unvaccinated child has died from #measles in the ongoing outbreak in Texas. This is incredibly sad and was also entirely preventable. Still waiting to hear from our HHS secretary...

submitted 1 day ago • 0 comments

Inexplicably, US administration has launched an unprecedented assault on science, on research institutions & on vital international organizations & initiatives. An assault on science anywhere is an assault on science everywhere; the global community must unite 🧪 www.nature.com/articles/d41...

submitted 2 days ago • 12 comments

🧵 (1/3) We have a massive measles outbreak in one of the largest states in the country. I have yet to see any major news outlet actively question the HHS secretary or HHS leadership. If this were happening under the previous administration, this lack of response would be all over the news. #MedSky

submitted 2 days ago • 1 comment

The immune system and your brain - join us on Thurs 24th April @crick.ac.uk (or virtually) for this year's World Immunology Day celebration www.crick.ac.uk/whats-on/wor...

submitted 3 days ago • 0 comments

🌟NEW in #NatureMedicine: Analysis of breast cancer incidence and mortality in 185 countries shows disparities between high-income and low and middle-income countries #OncSky #MedSky #BreastCancer www.nature.com/articles/s41...

submitted 3 days ago • 0 comments

🚗 Nice write-up in @nature.com about our recent #NatureMedicine #CARTcells paper, which can be found here: www.nature.com/articles/s41... #OncSky #MedSky #PedSky #immunotherapy

submitted 5 days ago • 0 comments

Texas won't do this analysis so ProPublica did 👏 Clear demo of how dangerous abortion bans are for women's health #MedSky

submitted 6 days ago • 0 comments

Meanwhile, crickets from the HHS and our new HHS secretary...this is the worst outbreak in Texas in 30 years surely it merits SOME guidance? And some advocacy/rapid support for MMR vaccination in the region? Would love to see more media outlets specifically ask the HHS for comment.

submitted 6 days ago • 0 comments

Incredible story -- in utero treatment (an oral gene-targeting drug) for Spinal Muscular Atrophy; the child is now almost 3 and has no signs of disease! www.nejm.org/doi/full/10....

submitted 6 days ago • 0 comments

🌟NEW in #NatureMedicine: the longest reported cancer remission after #CARTcell therapy (19 years)! No additional therapy needed. Encouraging news for the ongoing development of #CARTcells in solid tumors #PedSky #OncSky #MedSky #immunotherapy #neuroblastoma www.nature.com/articles/s41...

submitted 9 days ago • 0 comments

Everyone, but especially parents, should be familiar with the CDC's recommended #vaccine schedule lest this go missing in the ongoing Trump admin purge 👇 Remember that you can get some shots earlier! The MMR vaccine can be started as early as 6 months (your 👶 will still need 2 more shots later).

submitted 13 days ago • 0 comments

Since RFK Jr just got confirmed today, I am taking this chance to share this wonderful @sciam.bsky.social piece on The Staggering Success of Vaccines www.scientificamerican.com/article/see-...

submitted 14 days ago • 10 comments

My editorial on the indirect cuts. This is an opportunity for campuses to come together to make the case for higher education. Leaders need to step up and ask for support and lead. www.science.org/doi/10.1126/...

submitted 16 days ago • 13 comments

🚗 NEW #NatureMedicine paper reports results from a first-in-human trial of CAR-macrophages! Safe & feasible to manufacture, efficacy limited. More work needed in this space! @natureportfolio.nature.com #immunotherapy #CARTcells #macrophages www.nature.com/articles/s41...

submitted 17 days ago • 0 comments

Thought it might be good to put some human faces on NIH indirects. We had an IT guy at Stanford who supported school of medicine even though he could have made way more at a tech company. Said both his parents died of cancer. Though not a researcher, this is the way he said he could help the mission

submitted 18 days ago • 2 comments

Using national registry data from Denmark, 30 maternal diagnoses linked to offspring autism were identified with most associations attributable to family-level factors rather than direct causal effects of maternal diagnoses, according to a paper in Nature Medicine. 🧪

submitted 20 days ago • 1 comment

A new issue of Cell is out, featuring the 4 winners of the Rising Black Scientists Awards. Their essays bring hope, inspiration and reinforce the importance of equity in science. Do take a moment to check them out: www.cell.com/cell/current @cp-cell.bsky.social

submitted 21 days ago • 5 comments

New out in #NatureMedicine: In the ph 3 #CEPHEUS trial, #daratumumab + bortezomib, lenalidomide & dexamethasone (D-VRd) in transplant-ineligible or transplant-deferred newly diagnosed #MultipleMyeloma showed deeper & more durable increase in #MRD responses vs VRd. www.nature.com/articles/s41...

submitted 22 days ago • 0 comments

Bravo @bmj.com! 👏

submitted 23 days ago • 0 comments

Yeah, I'm sure that RFK Jr will do this /s 🙄 And even if he does, what then will you do? Based on past experience, absolutely nothing. This performative monologue may ease your conscience, Sen Cassidy, but you have abandoned the oath you took as a doctor. Shameful.

submitted 23 days ago • 0 comments

Here is a gift link to this excellent article that paints a realistic picture of what a less vaccinated America will look like. There are ongoing measles outbreaks in Houston and Atlanta to large cities. CDC can't update on these. www.theatlantic.com/health/archi...

submitted 26 days ago • 9 comments

Vaccines have saved + continue to save millions of lives from infectious diseases. It is normal to have questions about how they work & what makes a successful vaccine. In that spirit here are 3 excellent articles from people worth listening to - pls share:

submitted 26 days ago • 1 comment

Thank you to @statnews.com for continuing to report on this and talking to actual people who are directly impacted. Researchers have not been "exaggerating" the purge of info at the CDC. Just because the CDC website is still live doesn't mean the changes in these last days are inconsequential.

submitted 25 days ago • 0 comments

PLEASE REPOST: Health equity researchers, Please let me know if your centers or programs are being altered, closed, or threatened by your universities to comply with new EOs or if staff are being laid off. Signal: usha.22 or 👇(Won't use anything without permission.) www.statnews.com/2025/01/25/t...

submitted 27 days ago • 1 comment

Timely and interesting interview with some of the organizers of March for Science in 2017. In the face of numerous attacks on science and health research, still waiting to see whether something similar emerges this time around @aniloza.bsky.social @statnews.com www.statnews.com/2025/01/31/t...

submitted 28 days ago • 0 comments

“This is clearly a high anxiety moment” Former NIH director Monica Bertagnolli details her concerns about Robert F. Kennedy Jr and his ‘Make America Healthy Again’ campaign https://go.nature.com/40ALHGC

submitted 28 days ago • 1 comment

Mifepristone, which is used in medication abortion, has been shown in numerous studies to be safe. In light of current events, also re-sharing this related & important #NatureMedicine study from last year. TLDR: telehealth medication abortion is safe and effective www.nature.com/articles/s41...

submitted 29 days ago • 0 comments

To help people understand the importance of NIH, share what you’ve used their funding for (in easily understandable terms). I’ll start: my NIH postdoc funding helped me develop and test AI tools that could identify skin cancer across diverse skin tones.

submitted 31 days ago • 43 comments

It's Nature Medicine's 30th birthday! 🎂🥳Please check out our anniversary series on the Future of Medicine: www.nature.com/collections/... I'm so proud to be a part of this team and the broader #clinical research ecosystem! #NatureMedicine @natureportfolio.bsky.social

submitted 31 days ago • 0 comments

Also just discussed at the #GI25 immuno-oncology session: phase 1 trial results of lymph node-targeting mKRAS peptide vaccine in #ColorectalCancer and #PancreaticCancer #NatureMedicine 🔗https://www.nature.com/articles/s41591-023-02760-3

submitted 33 days ago • 0 comments

Just mentioned at the immuno-oncology session at #GI25 -- Learn more about the trial results of the combo of anti-PD-1, an HDAC inhibitor and anti-VEGF in MSS #ColorectalCancer in this 2024 #NatureMedicine paper: www.nature.com/articles/s41...

submitted 33 days ago • 0 comments

New research just presented at #GI25: BREAKWATER study finds 1L EC + mFOLFOX6 improves outcomes in BRAFV600E-mutant mCRC, offering new SOC: brnw.ch/21wQfxm #ASCODailyNews #GICSM

submitted 33 days ago • 0 comments

📰 hot off the press in #NatureMedicine & presented today at #GI25: The phase 3 #BREAKWATER trial in patients w/ BRAFV600E metastatic #ColorectalCancer 🗝️ finding: Encorafenib + cetuximab + mFOLFOX6 ⬆️ ORR vs standard of care www.nature.com/articles/s41... #OncSky #CRCSM @natureportfolio.bsky.social

submitted 33 days ago • 0 comments

Want to learn more about botensilimab and balstilimab treatment safety and efficacy in patients with #ColorectalCancer? Check out the phase 1 trial results published in #NatureMedicine last year #GI25 #OncSky #Immunotherapy www.nature.com/articles/s41...

submitted 33 days ago • 0 comments

How a heart medication—digoxin—might help prevent cancer spread by dissolving clusters of circulating tumor cells www.nature.com/articles/s41...

submitted 35 days ago • 14 comments

New out in #NatureMedicine: A phase 1 trial shows that the size of #CTC clusters (which can promote metastatic spread) can be reduced by treatment with the Na+/K+ ATPase inhibitor #digoxin in patients with metastatic #BreastCancer. By Nicola Aceto et al. www.nature.com/articles/s41...

submitted 34 days ago • 0 comments

Science Research Matters! Sharing this incredibly inspiring story of a very brave patient enrolled in a trial we recently published #NatureMedicine #OncSky #MedSky #PedSky @nickvitanza.bsky.social www.seattlechildrens.org/research/fea...

submitted 34 days ago • 0 comments

Why should the public care about the freeze on the NIH? Aside from the need for scientific pursuits to make our society better… -For every dollar we invest in NIH research, there is a $2.5 return. -Research dollars help fund universities that employ non-academics. (1/)

submitted 36 days ago • 33 comments

👏 Great keynote from @pamelakunzmd.bsky.social at #GI25 talking about the importance of inclusivity in medicine. During such a sad week, it's nice to hear a note of hope.

submitted 35 days ago • 0 comments