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saklad.bsky.social
Clin Prof Emeritus at UT Austin, Col of Pharm, Div of PTherapy & Trans Sci, based in San Antonio. PharmD, BCPP, AAPP, clin care, CNS disorders & treatment, consultant for clin care & research, tech, space, equality, diversity, climate, & civility.
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Last week NOAA, the parent agency of the National Weather Service (NWS), laid off hundreds of probationary employees (10% of total workforce). Apparently the plan is to lay off 50% of its staff in total. #Science www.theverge.com/news/622990/...

Strategy:When Trump voters express regret for their vote. 1)Don’t make them feel foolish or dumb. 2)Acknowledge their regret.3) Flip the blame to Fox News for failing to truthfully inform them about the GOP agenda. Welcome them to the resistance.

This was posted as a full page paid advertisement in today’s New York Times

It turns out that 500 units of Yellow Fever vaccine is effective. The “standard”dose is 14,000 units. #Medsky #IDsky www.nejm.org/doi/10.1056/...

I bought a Tesla Model Y before Musk turned to the “dark side” and became “Darth Musk.” It is still a fantastic car. It really makes me sad.

At least some meetings essential to approving new grants by the National Institutes of Health will be back on track later this month. scim.ag/41FbfEg

This makes perfect sense, if the US is now led by a Russian.

www.politico.com/news/2025/03...

The White House Office of Management and Budget, sent directed agency heads to submit two-step plans for significant ‘reductions in force’ by 13 March and 14 April. This will cripple science in the US and kneecap our government. #Medsky www.nature.com/articles/d41...

Cross-sectional analysis of Instagram and TikTok posts discussing medial tests found 982 posts followed by >194 million & found that they mentioned: • Benefits 87.1% • Potentional harms 14.7% • Overdiagnosis 6.1% • Scientific evidence in only 6.4% #Medsky jamanetwork.com/journals/jam...

This story is tough to summarize in a catchy way, but I'll try: The DHS asked the IRS to share the home addresses of 700,000 people suspected of being in the country illegally, and the IRS said no because that's not legal. Nixon was nearly impeached for a similar move. gift link: wapo.st/4bkjoAY

“Measles parties” were a bad idea even before the measles vaccine became available in 1963. Measles is dangerous: otitis media 7–9%, pneumonia 1–6%, diarrhea 8%, postinfectious encephalitis 1/1,000, subacute sclerosing panencephalitis 1/10,000, and mortality 1/1,000. arstechnica.com/health/2025/...

Blue Ghost lunar lander targets early morning Sunday for landing www.space.com/blue-ghost-l...

A school-age child with measles died in Texas this week, making it the first measles death in the U.S. in 10 years. Measles was an illness the U.S. had officially eliminated 25 years ago. #Medsky #IDsky apple.news/AOLVAVy1BQFW...

Netanyahu’s rejection of Saudi peace offering after 2014 Gaza war appears to have set up Hamas attack on October 7th. www.timesofisrael.com/report-netan...

The chaos of Trump's first month in office is no accident. This gutting of the federal government and impounding of Congressionally allocated funds was laid out years ago by Russell Vought, Trump's OMB director and Project 2025 architect. Todd Beeton looked at his core beliefs for The Big Picture.

We’ve tried to shelter our minds but tonight we’re preparing for the genocide of Science. Entire NIH departments will have no leaders. World renowned Scientists kicked to the curb without cause, & grants will loose their lead investigators. Is this what they want? Chaos? Destruction?

Breaking: RFK Jr. moves to quietly eliminate public comment from HHS's decision making: www.statnews.com/2025/02/28/r...

The dismantling of the US research enterprise has reached Antartica. www.wired.com/story/doge-a...

Texas leaders remain quiet amid measles crisis, now up to 146 Ina month. #Medsky #IDsky apple.news/AviX8NZDaRn-...

Researchers at Mass General Brigham found that a nasal spray delivering anti-CD3 (Foralumab) reduces neuroinflammation, limits central nervous system damage and improves behavioral outcomes in mice with traumatic brain injury. #Medsky www.technologynetworks.com/drug-discove...

In a Swedish cohort study, current antidepressant use and higher doses were associated with faster cognitive decline. No causality can be inferred, but caution and careful patient selection is warranted. [open access article] #Medsky bmcmedicine.biomedcentral.com/articles/10....

CDC finally has a press release on the Texas Measles Outbreak. BTW: Measles infection is very severe in a very large fraction of those infected, particularly those unvaccinated. #Medsky #IDsky www.cdc.gov/media/releas...

CDC has noted anecdotally reported uptick of children in the US that are critically ill with the flu: seizures, delirium, hallucinations, decreased consciousness, lethargy, personality changes, and abnormalities in brain imaging. #Medsky #IDsky arstechnica.com/health/2025/...

If someone thinks the measles outbreak and childhood death in Texas are "not unusual" or "happens all the time", they are deeply misinformed. h/t @adamratnermd.bsky.social for the inspiration. blogs.jwatch.org/hiv-id-obser...

At a public event last week, Lt. Gov. Dan Patrick said higher ed would get less funding if they don’t “kick DEI out of their schools,” a few weeks after lawmakers proposed a massive cut to public universities.

The FDA has canceled the vaccine advisory committee meeting scheduled every March to select the flu vaccine strains for next fall’s vaccinations. CDC data shows the flu caused ~910,000 hospitalizations since October. #Medsky #IDsky www.cnbc.com/2025/02/26/f...

America Has a Rogue President By Frank Kendall Former secretary of the Air Force “President Trump’s decision to fire senior military leaders without cause is foolish and a disgrace. It politicizes our professional military in a dangerous and debilitating way.”— www.nytimes.com/2025/02/24/o...

Axsome & Teva settle litigation over Auvelity (bupropion + dextromethorphan) by granting Teva a license to sell its generic version possibly as early as 09/30/2038. #Medsky drugstorenews.com/axsome-teva-...

www.nature.com/articles/d41...

OK patriots, the White House’s punishment of the AP for not genuflecting at Trump’s name change was a raw violation of the most fundamental 1st Am principle, & it will not stand Trump vs. the Media: He Won Round One, but He’s Going to Lose Bigly newrepublic.com/article/1920... via @newrepublic.com

Unvaccinated Child Dies of Measles in Texas. Over 124 cases of measles have been identified in Texas since late January, mostly among children and teenagers who are either unvaccinated or whose vaccination status is unknown. (Paywall unlocked) #Medsky www.nytimes.com/2025/02/26/u...

www.nature.com/articles/d41...

BREAKING: Inches from complete disaster. What is happening at the FAA?

www.nature.com/articles/d41...

21 federal technology staffers resigned from DOGE: “We swore to serve the American people and uphold our oath to the Constitution across presidential administrations. However, it has become clear that we can no longer honor those commitments.” apnews.com/article/doge...

Clozapine REMS reporting no longer required by FDA. The FDA recommends that current monitoring frequency continue. #Medsky www.fda.gov/drugs/postma...

apnews.com/article/fda-... FDA moves to rehire medical device, food safety and other staffers fired days earlier

What is RFK Jr doing about this? Has he made any statement? Does he think measles is a good way for kids to die? wapo.st/4hRbPEj

Not all generic drugs are equivalent. Some manufacturers account for a far larger share of adverse effect reports than others. #Medsky journals.sagepub.com/doi/abs/10.1...

www.tpr.org/public-healt...

AP sues Trump White House for denying access over 'Gulf of Mexico' row www.npr.org/2025/02/21/n...

So the President not only fired the Chairman of the Joint Chiefs. He also fired the top JAGs at the Army, Navy and Air Force. Those are the lead people who determine what is a legal order and what is not. So if you're planning to do things that are illegal they're the most obvious obstacle.

apnews.com/article/supr...

apple.news/AlDVVeuWXTKa...

Bit surprised, but the #H5N1 #birdflu case in Ohio tested positive in the hands of the #CDC. Had been told there wasn't a lot of virus in the sample and they might not be able to confirm. That brings the confirmed national total since March 2024 to 70 human cases. www.cdc.gov/bird-flu/sit...

Measles is a disease with a high degree of bad outcomes. It is the most infectious disease known. It should never happen. Someone is to blame. #Medsky arstechnica.com/health/2025/...

This doesn’t end well, does it?